Selective Estrogen Receptor Modulators, Antonio Cano; Joacquim Calaf i Alsina; Jose Luis D

Автор: Behl Christian
Название: Estrogen - Mystery Drug for the Brain? / The Neuroprotective Activities of the Female Sex Hormone
ISBN: 3211835393 ISBN-13(EAN): 9783211835395
Издательство: Springer
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Цена: 130430.00 T
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Описание: It is well known that estrogen is "somehow” a protective hormone for various age-related disorders. This book provides a solid knowledge of estrogen’s neuroprotective activities in the brain with a special emphasis on neurodegenerative disorders such as Alzheimer’s Disease. The focus is (1) to describe the biochemical, molecular, and cellular basis of the protective activity of estrogen and (2) to transfer this knowledge into the hospitals by discussing preventive and therapeutic approaches such as estrogen replacement therapy for post-menopausal women. Besides up-to-date information on estrogen and the brain, this book explains in a highly understandable manner molecular and cellular techniques by which basic data have been collected. The reader, which may include the professional specialist as well as the interested non-specialist, will also gain insight into the scientific transfer process of knowledge from basic science to the clinical situation and therefore "from bench to bed”.

Автор: Jordan V Craig
Название: Estrogen Action, Selective Estrogen Receptor Modulators and
ISBN: 1848169574 ISBN-13(EAN): 9781848169579
Издательство: World Scientific Publishing
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Цена: 179520.00 T
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Описание: Presents the evolution of the authors` ideas about estrogen action and its modulation by a fresh group of drugs called SERMs (Selective Estrogen Receptor Modulators). This title presents a journey over years of discovery and success in advancing women`s health, with the prospect of improved medicinal chemistry for the future.

Автор: Niels Bergemann; Anita Riecher-R?ssler
Название: Estrogen Effects in Psychiatric Disorders
ISBN: 3709117070 ISBN-13(EAN): 9783709117071
Издательство: Springer
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Цена: 102480.00 T
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Описание: A number of studies, mostly focusing on estrogen replacement therapy in women, have reported beneficial actions of these hormones on various neurobiological and neuropathological parameters in health and disease.

Автор: Felix Bronner; Mary C. Farach-Carson; Helmtrud I.
Название: Bone-Metabolic Functions and Modulators
ISBN: 144717156X ISBN-13(EAN): 9781447171560
Издательство: Springer
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Цена: 158380.00 T
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Описание: Recent research, which Bone- Metabolic Function and Modulators expands on, has added new support to the idea that bone not only serves as a support system, but also functions as an integrating organ, with a significant regulatory role for lipid and energy metabolism. Links between physical activity and the skeleton are also becoming increasingly clear. This fully illustrated volume contains up-to-date information on the metabolic role of the skeleton and what this can mean for the treatment of metabolic as well as skeletal and auditory diseases. Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development Bone- Metabolic Function and Modulators is of particular interest to clinician scientists, clinical and basic bone researchers, orthopedists, endocrinologists, internists, dentists, nurse practitioners, medical and dental residents and physiotherapists as well as students of the musculoskeletal system. Bone- Metabolic Function and Modulators is the seventh volume in the series Topics in Bone Biology, edited by Felix Bronner and Mary C. Farach-Carson. Other titles in this series:- Bone Formation Bone Resorption Engineering of Functional Skeletal Tissues Bone and Osteoarthritis Bone and Cancer Bone and Development

Автор: Andrea Manni; Michael Verderame
Название: Selective Estrogen Receptor Modulators
ISBN: 1468496654 ISBN-13(EAN): 9781468496659
Издательство: Springer
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Цена: 102480.00 T
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Описание: Experimental and clinical researchers from a wide range of disciplines present a wealth of fresh scientific information on the biochemistry, molecular biology, pharmacology, and clinical activity of SERMs.

Автор: Kenneth S. Korach; Tim Wintermantel
Название: Tissue-Specific Estrogen Action
ISBN: 3642421032 ISBN-13(EAN): 9783642421037
Издательство: Springer
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Цена: 130590.00 T
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Описание: Current molecular understanding of estrogen action has greatly profited from advances in molecular cell biology. These advances, and their implications for clinical use, were discussed by leading researchers from industry and academia during an international symposium held in Berlin, 1-3 March 2006 and are featured in this volume.

Автор: Kenneth S. Korach; Alexander Hillisch; Karl Heinri
Название: New Molecular Mechanisms of Estrogen Action and Their Impact on Future Perspectives in Estrogen Therapy
ISBN: 3662053888 ISBN-13(EAN): 9783662053881
Издательство: Springer
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Цена: 93160.00 T
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Описание: The evidence that these effects are mediated through the estrogen receptor(s) is based on similar but not always identical phenotypes as observed in experimental animal models of estrogen receptor mutations as well as the single clinical case of an estrogen receptor alpha mutant patient.

Автор: Kathleen M. Eyster
Название: Estrogen Receptors
ISBN: 1493931261 ISBN-13(EAN): 9781493931262
Издательство: Springer
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Цена: 116450.00 T
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Описание:

This volume examines a wide array of vital technologies for advancing our understanding of the receptor-mediated actions of estrogen. The protocols in this book range from standard methods and vital laboratory workhorses, such as receptor binding assays and western blot, to newer technologies such as RNAseq and proximity ligation assay. Chapters also discuss protocols from a broad range of tissue types to demonstrate the variety of estrogen receptor effects. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls.

Cutting-edge and thorough, Estrogen Receptors: Methods and Protocols is a detailed and helpful resource for scientists who are intrigued by the many facets of estrogen.

The chapter 'Bioinformatics Analysis of Estrogen-Responsive Genes' is open access under a CC BY 4.0 license.