Vaccines for Invasive Fungal Infections, Markus Kalkum; Margarita Semis
Автор: R. Pandey; S. H?glund; G. Prasad Название: Veterinary Vaccines ISBN: 1461392284 ISBN-13(EAN): 9781461392286 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Solid-phase synthesis of peptides is leading to an array of synthetic vaccines, an approach that is expected to attain its full potential once the sequences activating suppressor cells are discovered and the rules for presentation of antigens to T and B cells are better worked out.
Автор: Grandi Название: Genomics,Proteomics & Vaccines.2004 ISBN: 0470856165 ISBN-13(EAN): 9780470856161 Издательство: Wiley Рейтинг: Цена: 195310.00 T Наличие на складе: Поставка под заказ. Описание: The complete genome sequences of many bacteria are available, and comparisons of pathogenic strains with non pathogenic relatives are becoming more common. This will enable researchers to target vaccine development towards specific gene products that traditional approaches of vaccine research failed to discover.
Автор: Natalia Savelyeva; Christian Ottensmeier Название: Cancer Vaccines ISBN: 3319239090 ISBN-13(EAN): 9783319239095 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In addition, the volume discusses the advances made with genetic vaccines, including recent advances with DNA vaccines and the rapid transition of mRNA vaccines from the laboratory to bedside.
Автор: Yehuda Shoenfeld,Nancy Agmon–Levin Название: Vaccines and Autoimmunity ISBN: 1118663438 ISBN-13(EAN): 9781118663431 Издательство: Wiley Рейтинг: Цена: 149900.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In light of the discovery of Autoimmune Syndrome Induced by Adjuvants, or ASIA, Vaccines and Autoimmunity explores the role of adjuvants specifically aluminum in different vaccines and how they can induce diverse autoimmune clinical manifestations in genetically prone individuals.
Автор: Andrew W. Artenstein Название: Vaccines: A Biography ISBN: 1489983627 ISBN-13(EAN): 9781489983626 Издательство: Springer Рейтинг: Цена: 153720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Why another book about vaccines? There are already a few extremely well-written medical textbooks that provide comprehensive, state-of-the-art technical reviews regarding vaccine science. Additionally, in the past decade alone, a number of engrossing, provocative books have been published on various related issues ra- ing from vaccines against specific diseases to vaccine safety and policy. Yet there remains a significant gap in the literature – the history of vaccines. Vaccines: A Biography seeks to fill a void in the extant literature by focusing on the history of vaccines and in so doing, recounts the social, cultural, and scientific history of vaccines; it places them within their natural, historical context. The book traces the lineage – the “biography” – of individual vaccines, originating with deeply rooted medical problems and evolving to an eventual conclusion. Nonetheless, these are not “biographies” in the traditional sense; they do not trace an individual’s growth and development. Instead, they follow an idea as it is conceived and dev- oped, through the contributions of many. These are epic stories of discovery, of risk-takers, of individuals advancing medical science, in the words of the famous physical scientist Isaac Newton, “by standing on the shoulders of giants. ” One grant reviewer described the book’s concept as “triumphalist”; although meant as an indictment, this is only partially inaccurate.
Автор: Ronald W. Ellis; Bernard R. Brodeur Название: New Bacterial Vaccines ISBN: 1461349028 ISBN-13(EAN): 9781461349020 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: New Bacterial Vaccines focuses upon unfulfilled needs for bacterial vaccines. The distinctive feature of this book is that it focuses upon new vaccines now under development by reviewing key issues for each vaccine target and new technologies being applied to developing new vaccines.
Автор: Josef Thalhamer; Richard Weiss; Sandra Scheiblhofe Название: Gene Vaccines ISBN: 3709119294 ISBN-13(EAN): 9783709119297 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The induction of antigen-specific immune responses after in vivo transfection with expression plasmids has triggered a revolution of vaccine research. After a first hype, evoked by the fascinating options of this method, clinical studies did not reach the ambitious aims and a phase of disillusion ensued. It became obvious that Gene vaccines displayed a weaker immunogenicity in humans than had been observed in the mouse models. Meanwhile these hurdles have been overcome and gene vaccines undergo a renaissance. The present book gives an update of the “world of naked gene vaccines”, namely DNA and RNA vaccines. Its content ranges from general mechanisms, inherent immunostimulatory properties and the vast potential to modulate immune responses, to recent successful clinical studies and approved veterinary gene vaccines. Beyond the state-of-the-art of genetic immunization, the reader will be stimulated with a chapter addressing “burning questions”.
Автор: Andrea Grignolio; Joan Rundo Название: Vaccines: Are they Worth a Shot? ISBN: 3319681052 ISBN-13(EAN): 9783319681054 Издательство: Springer Рейтинг: Цена: 27940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: 1. The parents of unvaccinated children
1.1. The 80s, the beginning of the crisis (or resistance)
1.2. Education about risk
1.3. Social changes: The doctor-patient relationship in jeopardy
1.4. Unexpected impact of late fecundity
2. A brief history of the anti-vaccination movements
2.1. The anti-vaccination movements between 1700 and 1800: Roots of obligation and objection
2.2. The anti-vaccination movements in 1900: Media and politics
3. Web alarms: autism, mercury and immune overload
3.1. Conspiracy on the Internet: separating fact from fiction
3.2. Economic criticism: Big Pharma and the allure of patents
3.3. Logic errors: the precautionary principle and the equal balance mistake
3.4. False or manipulated data: Autism
3.5. Prejudices and ideologies: Purported overload and weakening of the immune system
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4. The antivax "experts" five ways to recognize them
4.1. Alternative philosophies: homeopathy, anthroposophy and Waldarf -Steiner schools
4.2. The "alternative therapies" Five clues that reveal a charlatan
5. Past, present, and future of vaccines
5.1. Evolutionary history of naturally acquired immunity
5.2. Artificially acquired immunity: success and safety of vaccines
5.3. Therapeutic vaccines of the future: cancer and neurodegenerative diseases
6. Conclusions
6.1. A new alliance between scientists and citizens for a "knowledge society"
6.2. Some tools for good communication strategies to combat anti-vaccination resistance
Название: Recombinant virus vaccines ISBN: 149396867X ISBN-13(EAN): 9781493968671 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Preface... Table of Contents... Contributing Authors...
Part I Double-Stranded DNA Viruses
1. Development of Novel Vaccines Against Infectious Diseases Based on Chimpanzee Adenoviral Vector Chao Zhang, Yudan Chi, and Dongming Zhou
2. Development of Recombinant Canarypox Viruses Expressing Immunogens Dйbora Garanzini, Marнa Paula Del Mйdico-Zajac, and Gabriela Calamante
3. Fowl Adenovirus-Based Vaccine Platform Juan C. Corredor, Yanlong Pei, and Йva Nagy
4. Development of Recombinant HSV-Based Vaccine Vectors Richard Voellmy and David Bloom
5. Generating Recombinant Pseudorabies Virus for Use as a Vaccine Platform Feifei Tan, Xiangdong Li, and Kegong Tian
6. Generation and Production of Modified Vaccinia Virus Ankara (MVA) as a Vaccine Vector Vincent Pavot, Sarah Sebastian, Alison V. Turner, Jake Matthews, and Sarah C. Gilbert
7. Poxvirus Safety Analysis in the Pregnant Mouse Model, Vaccinia and Raccoonpox Viruses Rachel L. Roper
Part II Negative Sense Single-Stranded RNA viruses
8. Development of Recombinant Arenavirus-Based Vaccines Luis Martнnez-Sobrido and Juan Carlos de la Torre
9. Development of Recombinant Measles Virus-Based Vaccines Michael D. Mьhlebach and Stefan Hutzler
10. Recombinant Tri-Segmented Pichinde Virus as a Novel Live Viral Vaccine Platform Rekha Dhanwani, Hinh Ly, and Yuying Liang
11. Human Rhinovirus-A1 as an Expression Vector Khamis Tomusange, Danushka Wijesundara, Eric James Gowans, and Branka Grubor-Bauk
12. Generating Recombinant Vesicular Stomatitis Viruses for Use as Vaccine Platforms John B. Ruedas and John H. Connor
Part III Positive Sense Single-Stranded RNA viruses
13. Alphavirus-Based Vaccines Kenneth Lundstrom
Part IV Bacteriophage
14. Display of HIV-1 Envelope Protein on Lambda Phage Scaffold as a Vaccine Platform Jonelle L. Mattiacio, Matt Brewer, and Stephen Dewhurst
15. Bacteriophage T4 as a Nanoparticle Platform to Display and Deliver Pathogen Antigens: Construction of an Effective Anthrax Vaccine Pan Tao, Qin Li, Sathish Shivachandra, and Venigalla B. Rao
Автор: Larry J. Anderson; Barney S. Graham Название: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines ISBN: 3662521555 ISBN-13(EAN): 9783662521557 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Автор: Larry J. Anderson; Barney S. Graham Название: Challenges and Opportunities for Respiratory Syncytial Virus Vaccines ISBN: 364238918X ISBN-13(EAN): 9783642389184 Издательство: Springer Рейтинг: Цена: 186330.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Although respiratory syncytial virus (RSV) has been a high priority for vaccine development for over 50 years now, still no vaccine is available and none has yet demonstrated sufficient promise to move to licensure.
Автор: Dushyant Varshney; Manmohan Singh Название: Lyophilized Biologics and Vaccines ISBN: 149392382X ISBN-13(EAN): 9781493923823 Издательство: Springer Рейтинг: Цена: 149060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Preface.- Part I - Lyophilization History and Fundamentals.- History of Lyophilization.- Heterogeneity of protein environments in frozen solutions and in the dried state.- Advance understanding of buffer behavior during lyophilization.- Advances in Instrumental Analysis Applied to the Development of Lyophilization Cycles.- New Developments in Controlled Nucleation: Commercializing VERISEQ(R) Nucleation technology.- Part II - Lyophilized Biologics and Vaccines - Modality Considerations.- Lyophilized Biologics.- Lyophilization of Therapeutic Proteins in Vials - Process Scale-up and Advances in Quality by Design.- Advances in Process Analytical Technology in Freeze Drying.- Process Scale-up and Optimization of Lyophilized Vaccine Products.- Stabilization of Plasmid DNA and Lipid-based Therapeutics as Dehydrated Formulations.- Part III - Advances in Alternate Drying.- Alternatives to Vial Lyophilization.- Spray Drying of Biopharmaceuticals.- Current Trends and Advances in Bulk Crystallization and Freeze Drying of Biopharmaceuticals.- Case Studies and Examples of Biopharmaceutical Modalities.- Processed by Bulk Crystallization or Bulk Freeze Drying.- Part IV- Regulatory, Packaging and Technology Transfer Considerations.- Lyophilization of Biologics - An FDA Perspective.- Recent Trends in Lyophilized Delivery Devices and Packaging.- Lyophilization Technology Transfer towards Product Launch.
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