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Molecular Profiling, Virginia Espina


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Автор: Virginia Espina
Название:  Molecular Profiling
ISBN: 9781493969890
Издательство: Springer
Классификация:

ISBN-10: 1493969897
Обложка/Формат: Hardcover
Страницы: 414
Вес: 0.96 кг.
Дата издания: 14.05.2017
Серия: Methods in Molecular Biology
Язык: English
Издание: 2nd ed. 2017
Иллюстрации: 46 tables, color; 45 illustrations, color; 23 illustrations, black and white; xiii, 414 p. 68 illus., 45 illus. in color.
Размер: 254 x 178 x 24
Читательская аудитория: Professional & vocational
Основная тема: Biomedicine
Подзаголовок: Methods and Protocols
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Германии
Описание:

1. Tumor Staging and Grading: A Primer

Stacy M. Telloni

2. Innovations in Clinical Trial Design in the Era of Molecular Profiling

Julia D. Wulfkuhle, Alexander Spira, Kirsten H. Edmiston, and Emanuel F. Petricoin

3. Personalized Medicine: Ethical Aspects

G. Terry Sharrer

4. Antibody Validation by Western Blotting

Michele Signore, Valeria Manganelli and Alex Hodge

5. Scanning Electron Microscopy Sample Preparation and Imaging

Jenny Ngoc Tran Nguyen and Amanda M. Harbison

Claudius Mueller, Michael G. Harpole, and Virginia Espina

7. Application of Hydrogel Nanoparticles for the Capture, Concentration, and Preservation of Low-Abundance Biomarkers

Ruben Magni and Alessandra Luchini

8. Using Laser Capture Microdissection to Isolate Cortical Laminae in Non-human Primate Brain

Brian A. Corgiat and Claudius Mueller

9. Western Blot Techniques

Brianna Kim

10. ELISA for Monitoring Nerve Growth Factor

Justin B. Davis

11. Reverse Phase Protein Microarrays

Elisa Baldelli, Valerie Calvert, Alex Hodge, Amy VanMeter, Emanuel F. Petricoin III, and Mariaelena Pierobon

12. Clustering and Network Analysis of Reverse-Phase Protein Array Data

Adam Byron

13. PCR: Identification of Genetic Polymorphisms

Amanda M. Harbison and Jenny Ngoc Tran Nguyen

14. Microsatellite Analysis for Identification of Individuals Using Bone from the Extinct Stellers Sea Cow (Hydrodamalis gigas)

Jeffery F. Warner, Michael G. Harpole, and Lorelei D. Crerar

15. Somatic DNA Mutation Analysis

Anthony OGrady and Robert Cummins

16. Optimization of Immunostaining for Prospective Image Analysis

Scott M. Lawrence and Yelena G. Golubeva

17. Fluorescence in situ Hybridization of Cells, Chromosomes, and Formalin Fixed Paraffin Embedded Tissues

Ahmad Alamri, Jun Yeb Nam, and Jan K. Blancato

18. High-Resolution Image Stitching as a Tool to Assess Tissue-Level Protein Distribution and Localization

Bryan A. Millis and Matthew J. Tyska

19. Mass Spectrometry Based Biomarker Discovery

Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo

20. Quantitative Mass Spectrometry by Isotope-Dilution and Multiple Reaction Monitoring (MRM)

Paul Russo, Brian L. Hood, Nicholas W. Bateman, Thomas P. Conrads

21. LC-Mass Spectrometry for Metabolomics Allyson L. Dailey

22. Metabolomic Bioinformatic Analysis

Allyson L. Dailey

23. Stable Isotope Quantitative N-glycan Analysis by Liquid Separation Techniques and Mass Spectrometry

Stefan Mittermayr, Simone Albrecht, Csaba Vбradi, Silvia Millбn-Martнn, and Jonathan Bones

24. Grant Writing Tips for Translational Research

Lindsay Wescott, Michael Laskofski, Donna Senator, and Carly Curran

25. Inventions and Patents: A Practical Tutorial

Hina Mehta, Lille Tidwell, and Lance A. Liotta

26. Product Development and Commercialization of Diagnostic or Life Science Products for Scientists and Researchers

Meghan M. Alonso



Molecular Profiling

Автор: Virginia Espina; Lance A. Liotta
Название: Molecular Profiling
ISBN: 1493956841 ISBN-13(EAN): 9781493956845
Издательство: Springer
Рейтинг:
Цена: 139750.00 T
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Описание:

Contents

Preface

Contributors

1. Tumor Staging and Grading: A Primer

Stacy M. Cowherd

2. Clinical Trial Design in the Age of Molecular Profiling

Alexander Spira and Kirsten H. Edmiston

3. Personalized Medicine: Ethics for Clinical Trials

G. Terry Sharrer

4. Reduction of Preanalytical Variability in Specimen Procurement for Molecular Profiling

Virginia Espina and Claudius Mueller

5. The Human Side of Cancer Biobanking

Eoin Gaffney, Deirdre Madden, and Geraldine A. Thomas

6. Introduction to Genomics

Luca Del Giacco and Cristina Cattaneo

7. Genomic Profiling: cDNA arrays and oligoarrays

Francesco Gorreta, Walter Carbone, Dagania Barzhagi

8. Genome wide methylation profiling in archival formalin fixed paraffin embedded (FFPE) tissue samples

J. Keith Killian, Robert L. Walker, Sven Bilke, Yidong Chen, Sean Davis, Robert Cornelison, William I. Smith, and Paul S. Meltzer

9. An Overview of microRNA Methods: Expression Profiling and Target Identification

Sinйad M Smith and David W Murray

10. Antibody Validation by Western Blotting

Michele Signore and K. Alex Reeder

11. Laser Capture Microdissection: ArcturusXT infra-red capture and UV cutting methods

Rosa I. Gallagher, Steven R. Blakely, Lance A. Liotta, and Virginia Espina

12. Antibody microarrays: Analysis of Cystic Fibrosis

Catherine E. Jozwik, Harvey B. Pollard, Meera Srivastava, Ofer Eidelman, QingYuan Fan, Thomas N. Darling, and Pamela L. Zeitlin

13. Tissue Microarrays As A Tool In The Discovery & Validation Of Predictive Biomarkers

Stephen M. Hewitt

14. Reverse phase protein microarrays

Mariaelena Pierobon, Francesca Galdi, Noemi Moroni, and Emanuel F. Petricoin III

15. Serum Low Molecular Weight Protein Fractionation for Biomarker Discovery

Amy VanMeter, Serena Camerini, Maria Letizia Polci, Alessandra Tessitore, Nishant Trivedi, Michael Heiby, Jonathan Hansen, and Weidong Zhou

16. Mass spectrometry based biomarker discovery

Weidong Zhou, Emanuel F. Petricoin III, and Caterina Longo

17. Mitochondrial Proteome: Toward The Detection and Profiling of Disease Associated Alterations

Paul C. Herrmann and E. Clifford Herrmann

18. Adult Neural Stem Cells: Isolation and Propagation

Jamin M. Lechter and Daniel N. Cox

19. Evanescent Wave Imaging: An Introduction to Total Internal Reflection Fluorescence Microscopy (TIRF)

Bryan A. Millis

20. Construction and Hyperspectral Imaging of Quantum Dot Lysate Arrays

Kevin P. Rosenblatt, Michael Huebschman, and Harold R. Garner

21. Microarray Data Analysis: Comparing Two Population Means

Jianghong Deng, Valerie S. Calvert and Mariaelena Pierobon

22. Bioinformatics/Biostatistics: microarray analysis

Gabriel S. Eichler

23. Structure-based functional design of drugs: from target to lead compound

Amy C. Anderson

24. Personalized Medicine: Changing the Paradigm of Drug Development

Robin Couch and Bryan T. Mott

25. Grant Writing Tips for the First Time Applicant

Lindsay Wescott and Michael Laskofski

26. Inventions and Patents: A practical tutorial

J. Lille Tidwell and Lance Liotta

27. Regulatory Approval Pathways for Molecular Diagnostic Technology

Lance Liotta and Emanuel Petricoin

28. Small business development for molecular diagnostics

Athanasia Anagnostou and Lance Liotta


Molecular Bioenergetics and Macromolecular Biochemistry

Автор: Hans H. Weber
Название: Molecular Bioenergetics and Macromolecular Biochemistry
ISBN: 3642653111 ISBN-13(EAN): 9783642653117
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
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Описание: The Meyerhof Symposium on "Molecular Bioenergetics and Macromolecular Biochemistry" took place in Heidelberg from the 5th to the 8th of July, 1970.

Molecular Databases for Protein Sequences and Structure Studies

Автор: John A.A. Sillince; Maria Sillince
Название: Molecular Databases for Protein Sequences and Structure Studies
ISBN: 3642768113 ISBN-13(EAN): 9783642768118
Издательство: Springer
Рейтинг:
Цена: 102480.00 T
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Описание: The authors introduce students entering research in molecular biology and related fields into the efficient use of the numerous databases available. The book is required reading for researchers and students who plan to use modern computer environment in their research.

Genetic and Molecular Basis of Plant Pathogenesis

Автор: J.E. Vanderplank
Название: Genetic and Molecular Basis of Plant Pathogenesis
ISBN: 3642669670 ISBN-13(EAN): 9783642669675
Издательство: Springer
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Цена: 121110.00 T
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Описание: As befits a volume in the Advanced Series in Agricultural Sciences, this book was written with problems of practical agriculture in mind. Half the book could not have been written 20 years ago, even if there had then been available all the literature that has since accumulated on the genetics and chemistry of plant disease.

Progress in Molecular and Subcellular Biology 3

Автор: Robert E. Rhoads
Название: Progress in Molecular and Subcellular Biology 3
ISBN: 3642655807 ISBN-13(EAN): 9783642655807
Издательство: Springer
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Цена: 121110.00 T
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Progress in Molecular and Subcellular Biology

Автор: S. Bram
Название: Progress in Molecular and Subcellular Biology
ISBN: 364266251X ISBN-13(EAN): 9783642662515
Издательство: Springer
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Цена: 121110.00 T
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Molecular Diagnostics of Cancer

Автор: Christoph Wagener; Siegfried Neumann
Название: Molecular Diagnostics of Cancer
ISBN: 3540554769 ISBN-13(EAN): 9783540554769
Издательство: Springer
Рейтинг:
Цена: 81050.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The present and potential future applications of new diagnostic strategies based on the direct or indirect detection of cancer genes are described in this volume. Among the methodologies covered are DNA fingerprinting, enzymatic target amplfication and the application of monoclonal antibodies.

The Molecular Biology of Autoimmune Disease

Автор: Andrew G. Demaine; J.-Paul Banga; Alan M. McGregor
Название: The Molecular Biology of Autoimmune Disease
ISBN: 3642751350 ISBN-13(EAN): 9783642751356
Издательство: Springer
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Цена: 121110.00 T
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Описание: Proceedings of the NATO Advanced Research Workshop on Molecular Biology and Autoimmune Disease held in Athens, Greece, from April 16-20, 1989

Chemical Relaxation in Molecular Biology

Автор: I. Pecht; M. Ehrenberg; R. Rigler; E. Grell; D.M.
Название: Chemical Relaxation in Molecular Biology
ISBN: 3642811191 ISBN-13(EAN): 9783642811197
Издательство: Springer
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Цена: 121110.00 T
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Описание: A systematic study traced the cause of this absorption, showing that the covered frequency range and the intensity of the absorption were related in a predictable manner to the rate at which ions can interact and form structures differing in volume from the non interacting species.

Molecular Mechanisms of Signalling and Membrane Transport

Автор: Karel W.A. Wirtz
Название: Molecular Mechanisms of Signalling and Membrane Transport
ISBN: 3642645593 ISBN-13(EAN): 9783642645594
Издательство: Springer
Рейтинг:
Цена: 121110.00 T
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Описание: Proceedings of the NATO Study Institute on Molecular Mechanisms of Signalling and Targeting, held on the Island of Spetsai, Greece, August 18-30, 1996

Molecular mechanisms and physiology of disease

Автор: Nilanjana Maulik; Tom Karagiannis
Название: Molecular mechanisms and physiology of disease
ISBN: 1493946234 ISBN-13(EAN): 9781493946235
Издательство: Springer
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Цена: 214280.00 T
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Описание: In a simplified form, epigenetics refers to heritable changes in phenotype that are not due to changes in the underlying DNA sequence. In this book, epigenetic mechanisms of regulation and dysregulation in health and disease are explored in great depth. Detailed chapters on epigenetic processes including DNA methylation and chromatin post-translational modifications including potential interventions with DNA methyltransferase inhibitors and histone deacetylase inhibitors are explored in initial chapters. These provide a detailed overview and important background to the entire field. The book is then focussed on epigenetic mechanisms involved in various diseases including anti-inflammatory and autoimmune conditions. Important accounts relating to the effects of epigenetics in metabolic syndrome, cardiovascular disease and asthma are the focus of subsequent chapters. The role of epigenetic dysregulation in malignancy is a current topic of interest and represents an intense field of research. A large component of this book is dedicated to the analysis of aberrant epigenetic processes in carcinogenesis and cancer progression. Further, chapters are focused on emerging cancer prevention using nutritional components and anti-cancer therapies particularly with histone deacetylase inhibitors, which have already been approved for the treatment of cutaneous T-cell lymphoma. The emerging role of nanoparticle preparations, especially in the context of delivering potential epigenetic therapies to target cells in various diseases, is also explored in this book. Overall, this book encompasses a wide range of topics related to epigenetic mechanisms in health and disease and would appeal to anyone with an interest in epigenetics, chromatin biology and emerging epigenetic interventions and therapies.

Molecular Radiation Biology

Автор: Hermann Dertinger; K.G. Zimmer; R.P.O. H?ber; P.A.
Название: Molecular Radiation Biology
ISBN: 0387900136 ISBN-13(EAN): 9780387900131
Издательство: Springer
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Цена: 69650.00 T
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