Directed enzyme evolution, 

Автор: Frances H. Arnold; George Georgiou
Название: Directed Evolution Library Creation
ISBN: 1617374717 ISBN-13(EAN): 9781617374715
Издательство: Springer
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Цена: 144410.00 T
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Описание: Biological systems are very special substrates for engineering--uniquely the products of evolution, they are easily redesigned by similar approaches. A simple algorithm of iterative cycles of diversification and selection, evolution works at all scales, from single molecules to whole ecosystems. In the little more than a decade since the first reported applications of evolutionary design to enzyme engineering, directed evolution has matured to the point where it now represents the centerpiece of industrial biocatalyst development and is being practiced by thousands of academic and industrial scientists in com- nies and universities around the world. The appeal of directed evolution is easy to understand: it is conceptually straightforward, it can be practiced without any special instrumentation and, most important, it frequently yields useful solutions, many of which are totally unanticipated. Directed evolution has r- dered protein engineering readily accessible to a broad audience of scientists and engineers who wish to tailor a myriad of protein properties, including th- mal and solvent stability, enzyme selectivity, specific activity, protease s- ceptibility, allosteric control of protein function, ligand binding, transcriptional activation, and solubility. Furthermore, the range of applications has expanded to the engineering of more complex functions such as those performed by m- tiple proteins acting in concert (in biosynthetic pathways) or as part of mac- molecular complexes and biological networks.

Автор: P. Boon Chock; Charles Y. Huang; C.L. Tsou; Jerry
Название: Enzyme Dynamics and Regulation
ISBN: 1461283302 ISBN-13(EAN): 9781461283300
Издательство: Springer
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Цена: 97820.00 T
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Описание: Papers contributed to the International Symposium on the Dynamics of Soluble and Immobilized Enzyme Systems, held May 26-30, 1986 in Beijing, China

Автор: W. J. Dickinson; D. T. Sullivan
Название: Gene-Enzyme Systems in Drosophila
ISBN: 3662219425 ISBN-13(EAN): 9783662219423
Издательство: Springer
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Цена: 46570.00 T
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Описание: We are convinced that the study of enzyme behavior during development merits much attention, particularly if the work is carried out on a eukaryote that lends itself to genetic and developmental analysis.

Автор: Thomas W. Traut
Название: Allosteric Regulatory Enzymes
ISBN: 1441944532 ISBN-13(EAN): 9781441944535
Издательство: Springer
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Цена: 186340.00 T
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Описание: This book covers the most recent developments in the analysis of allosteric enzymes. It provides a logical introduction to the limits for enzyme function as dictated by the factors that are limits for life.

Автор: A. Azzi; U. Brodbeck; P. Zahler
Название: Enzymes, Receptors, and Carriers of Biological Membranes
ISBN: 3540137513 ISBN-13(EAN): 9783540137511
Издательство: Springer
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Цена: 102480.00 T
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Описание: With contributions by numerous experts

Автор: Michael M. Burrell
Название: Enzymes of Molecular Biology
ISBN: 0896033228 ISBN-13(EAN): 9780896033221
Издательство: Springer
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Цена: 135090.00 T
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Описание: To aid the process of investigation, the Methods Molecular Biology series has brought together many protocols and has highlighted the useful variations and the pitfalls of the different methods. This information, though usually available in the literature, is often widely dispersed and frequently occurs in older volumes of journals;

Автор: Michael M. Burrell
Название: Enzymes of Molecular Biology
ISBN: 0896032345 ISBN-13(EAN): 9780896032347
Издательство: Springer
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Цена: 135090.00 T
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Описание: To aid the process of investigation, the Methods Molecular Biology series has brought together many protocols and has highlighted the useful variations and the pitfalls of the different methods. This information, though usually available in the literature, is often widely dispersed and frequently occurs in older volumes of journals;

Автор: Alan A. Boulton; Glen B. Baker; Peter H. Yu
Название: Neurotransmitter Enzymes
ISBN: 0896030792 ISBN-13(EAN): 9780896030794
Издательство: Springer
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Цена: 172350.00 T
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Описание: Similar reasons exist for Volume 4 on receptor binding techniques since experimental details are provided for all types of ligand-receptor binding, including chapters on general principles, drug discovery and development, and a most useful-appendix on computer programs for Scatchard, nonlinear, and competitive d- placement analyses.

Автор: Jose M. Guisan
Название: Immobilization of Enzymes and Cells
ISBN: 1493959883 ISBN-13(EAN): 9781493959884
Издательство: Springer
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Цена: 111790.00 T
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Описание: This book features step-by-step, readily reproducible laboratory protocols for the preparation, characterization, and utilization of immobilized enzymes and cells. It also features key notes and implementation advice from experts.

Название: Dna repair enzymes
ISBN: 0128118466 ISBN-13(EAN): 9780128118467
Издательство: Elsevier Science
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Цена: 162820.00 T
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Описание:

DNA Repair Enzymes, Part A, Volume 591 is the latest volume in the Methods in Enzymology series and the first part of a thematic that focuses on DNA repair enzymes. Topics in this new release include chapters on the Optimization of Native and Formaldehyde iPOND Techniques for Use in Suspension Cells, the Proteomic Analyses of the Eukaryotic Replication Machinery, DNA Fiber Analysis: Mind the Gap , Comet-FISH for Ultrasensitive Strand-Specific Detection of DNA Damage in Single Cells, Examining DNA Double-Strand Break Repair in a Cell Cycle-Dependent Manner, Base Excision Repair Variants in Cancer, and Fluorescence-Based Reporters for Detection of Mutagenesis in E. coli.

Автор: Guisan, Jose M.
Название: Immobilization of enzymes and cells
ISBN: 1627035494 ISBN-13(EAN): 9781627035491
Издательство: Springer
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Цена: 167700.00 T
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Описание: This book features step-by-step, readily reproducible laboratory protocols for the preparation, characterization, and utilization of immobilized enzymes and cells. It also features key notes and implementation advice from experts.

Автор: Donev, Rossen
Название: Enzymes Mechanisms and Dynamics: Insights from Experimental and C
ISBN: 0128048255 ISBN-13(EAN): 9780128048252
Издательство: Elsevier Science
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Цена: 141480.00 T
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Описание:

Insights into Enzyme Mechanisms and Functions from Experimental and Computational Methods is the latest volume in the popular Advances in Protein Chemistry and Structural Biology series, an essential resource for protein chemists. Each volume brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.