Mammalian Transient Receptor Potential (TRP) Cation Channels, Bernd Nilius; Veit Flockerzi

Название: Receptor and Ion-channel Trafficking: Cell Biology of Ligand-gated and Voltage-sensitive Ion Channels
ISBN: 0192632248 ISBN-13(EAN): 9780192632241
Издательство: Oxford Academ
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Цена: 250800.00 T
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Описание: This book reviews the recent advances in our understanding of the the molecular and cellular mechanisms regulating the targeted movement (trafficking) of receptors and ion channels in neurones - mechanisms fundamental to synaptic function.

Автор: Bernd Nilius; Veit Flockerzi
Название: Mammalian Transient Receptor Potential (TRP) Cation Channels
ISBN: 364254214X ISBN-13(EAN): 9783642542145
Издательство: Springer
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Цена: 354040.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In this fast moving field the main goal of this volume is to provide up-to-date information on the molecular and functional properties and pharmacology of mammalian TRP channels. Leading experts in the field will describe properties of a single TRP protein/channel or portray more general principles of TRP function and important pathological situations linked to mutations of TRP genes or their altered expression. Thereby this volume on Transient Receptor Potential (TRP) Channels provides valuable information for readers with different expectations and backgrounds, for those who are approaching this field of research as well as for those wanting to make a trip to TRPs.

Автор: Arpad Szallasi
Название: TRP Channels as Therapeutic Targets
ISBN: 0124200249 ISBN-13(EAN): 9780124200241
Издательство: Elsevier Science
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Цена: 154960.00 T
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Описание: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. . This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. . An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. . Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings.

Автор: A. Cato; H. Schaecke; K. Asadullah
Название: Recent Advances in Glucocorticoid Receptor Action
ISBN: 3662046628 ISBN-13(EAN): 9783662046623
Издательство: Springer
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Цена: 174150.00 T
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Автор: Jose Luis Millan
Название: Mammalian Alkaline Phosphatases: From Biology to Applications in Medicine and Biotechnology
ISBN: 3527310797 ISBN-13(EAN): 9783527310791
Издательство: Wiley
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Цена: 116160.00 T
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Описание: A review and discussion of new knowledge on the structure and function of mammalian alkaline phosphatases (APs) gained over the last 25 years. It covers: the structure, regulation and expression of the AP genes; the three-dimensional structure of APs and mutagenesis work that further defined the structural/functional domains of the isozymes; the phenotypic abnormalities of the different AP knockout mice; and our current understanding of the in vivo role of the AP isozymes. The book also describes the possible use of APs as therapeutic agents and therapeutic targets and the many uses of these enzymes in clinical medicine and in biotechnology.