Advances in Tumor Immunology and Immunotherapy, Joseph D. Rosenblatt; Eckhard R. Podack; Glen N. B
Автор: Yotnda Название: Immunotherapy of Cancer ISBN: 1607617854 ISBN-13(EAN): 9781607617853 Издательство: Springer Рейтинг: Цена: 153720.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes detailed procedures for trainees and experts in the area of basic, clinical science who wish to undertake their own cutting-edge immunotherapy studies. It includes coverage of pre-clinical models for cancer immunotherapy.
Автор: Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642141358 ISBN-13(EAN): 9783642141355 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The interplay between tumors and their immunologic microenvironment is complex, difficult to decipher, but its understanding is of seminal importance for the development of novel prognostic markers and therapeutic strategies. The present review discusses tumor-immune interactions in several human cancers that illustrate various aspects of this complexity and proposes an integrated scheme of the impact of local immune reactions on clinical outcome. Current active immunotherapy trials have shown durable tumor regressions in a fraction of patients. However, clinical efficacy of current vaccines is limited, possibly because tumors skew the immune system by means of myeloid-derived suppressor cells, inflammatory type 2 T cells and regulatory T cells (Tregs), all of which prevent the generation of effector cells. To improve the clinical efficacy of cancer vaccines in patients with metastatic disease, we need to design novel and improved strategies that can boost adaptive immunity to cancer, help overcome Tregs and allow the breakdown of the immunosuppressive tumor microenvironment.
Автор: George C. Prendergast Название: Cancer Immunotherapy, ISBN: 0123942969 ISBN-13(EAN): 9780123942968 Издательство: Elsevier Science Рейтинг: Цена: 107790.00 T Наличие на складе: Поставка под заказ. Описание: There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles.
Автор: Glenn Dranoff Название: Cancer Immunology and Immunotherapy ISBN: 3642267882 ISBN-13(EAN): 9783642267888 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Cancer Immunotherapy discusses tumor-immune interactions in several human cancers. The text proposes an integrated scheme of the impact of local immune reactions on clinical outcome, and illustrates various aspects of this complexity.
Автор: Mary L. Disis Название: Immunotherapy of Cancer ISBN: 1617376450 ISBN-13(EAN): 9781617376450 Издательство: Springer Рейтинг: Цена: 243800.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Expert bench and clinical scientists join forces to concurrently review both the state-of-the-art in tumor immunology and its clinical translation into promising practical treatments.
Автор: Britten Название: Cancer Immunotherapy Meets Oncology ISBN: 3319051032 ISBN-13(EAN): 9783319051031 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ.
Автор: Xiang-Yang Wang Название: Immunotherapy of Cancer,128 ISBN: 0128023163 ISBN-13(EAN): 9780128023167 Издательство: Elsevier Science Рейтинг: Цена: 132500.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Immunotherapy of Cancer provides information on cancer research related to inflammation and immunity, containing outstanding reviews by experts in the field. It is suitable for researchers and students who have an interest in cancer immunobiology.
Автор: Donnadieu Название: Defects in T Cell Trafficking and Resistance to Cancer Immunotherapy ISBN: 3319422219 ISBN-13(EAN): 9783319422213 Издательство: Springer Рейтинг: Цена: 139310.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume focuses on recent advances in understanding T cells as key players in antitumor immune responses, and as a result T cell-based immunotherapy is starting to transform the treatment of advanced cancers. However, despite recent successes, many patients with cancer fail to respond to these treatments. Defective migration of T cells into and within tumors is considered as an important resistance mechanism to cancer immunotherapy.
The volume includes three sections. The first section covers general knowledge about T cell trafficking during a normal immune response but also during tumor development. The second section provides an in-depth description of the different obstacles that prevent T cells from migrating and contacting tumor cells. The third section explores therapeutic strategies to improve trafficking of T cells into tumors and, thus, to enhance the effectiveness of cancer immunotherapy.
Автор: Zhang Название: Progress in Cancer Immunotherapy ISBN: 9401775532 ISBN-13(EAN): 9789401775533 Издательство: Springer Рейтинг: Цена: 148020.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Thisbook provides readers an extensive overview of recent progress in basicand clinical research on cancer immunotherapy. Thanks to rapid advances inmolecular biology and immunology, it has become increasingly evident thatcancer growth is influenced by host immune responses. With the success of anumber of clinical trials, immunotherapy has become a promising treatmentmodality of cancer. This book covers five major topics, including monoclonalantibodies, biological response modifiers, cancer vaccines, adoptive cellulartherapy and oncolytic viruses. It also examines the combination of differentimmune strategies as well as the combination of immunotherapy with othertreatments to increase anti-tumor effects. Throughthecomprehensive discussion of the topic, the book sheds valuable new light on thetreatment of tumors.
Автор: Rees Robert C. Название: Tumor Immunology and Immunotherapy ISBN: 0199676860 ISBN-13(EAN): 9780199676866 Издательство: Oxford Academ Рейтинг: Цена: 240240.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Tumor immunology and immunotherapy provides a comprehensive account of cancer immunity and immunotherapy. Examining recent results, current areas of interest and the specific issues that are affecting the research and development of vaccines, this book provides insight into how these problems may be overcome as viewed by leaders in the field.
Автор: W. I. Wei Название: Tumors of the Nose, Sinuses and Nasopharynx ISBN: 3131471913 ISBN-13(EAN): 9783131471918 Издательство: Thieme Verlagsgruppe Цена: 115610.00 T Наличие на складе: Нет в наличии. Описание: "This is a well-written, excellently referenced text that will truly be the leading text in its field. It will be an essential text for every skull base surgeon to have on his or her bookshelf to use as a reference and to read before tackling the more uncommon pathologies that exist in this area." -- Neurosurgery Covering tumors of the nose, sinuses, and nasopharynx for the first time in a single volume, this book is essential for all specialists. It incorporates the newest techniques for evaluation and treatment, including endoscopic approaches to the skull base, and offers a wealth of evidence-based data and analysis. For all members of the multidisciplinary health care teams who manage these complex cases, this book makes a major contribution to the field. Special Features: Written by three international authorities who have published and lectured widely and conducted landmark studies in this area Covers the full range of benign and malignant nose and sinus tumors, as well as the specific nasopharyngeal tumors that are more common to certain geographic regions (Far East) and ethnic groups (Chinese origin) Content is based on one of the largest single institutional studies ever undertaken, plus an extensive review of the international literature Encompasses every aspect of the field, from etiology, clinical features, histology, imaging studies, and diagnosis to natural history, treatment options, outcomes, and management of residual or recurrent disease Includes up-to-date contributions from experts on chemoradiation and head and neck imaging With the goal of centralizing data and long-term follow-up, this comprehensive guide is invaluable for all otolaryngologists, head and neck surgeons, oncologists, neurosurgeons, and maxillofacial and plastic surgeons who treat patients with challenging sinonasal, skull base, and nasopharyngeal neoplasms. Thieme eOtolaryngology is the premier online resource for otolaryngology-head and neck surgery. For a free trial, go to: thieme.com/eototrial
Автор: Benjamin Bonavida; Salem Chouaib Название: Resistance of Cancer Cells to CTL-Mediated Immunotherapy ISBN: 3319178067 ISBN-13(EAN): 9783319178066 Издательство: Springer Рейтинг: Цена: 139750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive volume explores the latest research on the mechanisms of resistance in cancer cells to CTL-mediated immunotherapy. Chapter topics discuss cell-mediated immunity as the result of cytotoxic T-lymphocytes (CTL) directed specifically against cancer cells. In addition, the volume reviews how CTL mediate the cytotoxic activity, in large part, by the indication of apoptosis; hence, tumor cells develop anti-apoptotic mechanisms and thereby, resist CTL-induced apoptosis. In order for CTL-mediated antitumor immunotherapy to be effective, it is essential that agents directed against the resistant tumor cells sensitized cancer cells for CTL-mediated apoptosis. Examples of such agents discussed in the volume include are HDAC inhibitors, proteasome inhibitors, Bcl-2 family inhibitors, PARP, antibodies, and more.
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