Biological and Medical Research in Space, David Moore; Peter Bie; Heinz Oser

Автор: Bhagavan N. V.
Название: Essentials of Medical Biochemistry, 2 ed.
ISBN: 0124166873 ISBN-13(EAN): 9780124166875
Издательство: Elsevier Science
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Цена: 105540.00 T
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Essentials of Medical Biochemistry, Second Edition: With Clinical Cases is the most condensed, yet detailed biochemistry overview available on the topic. It presents contemporary coverage of the fundamentals of biochemistry, emphasizing relevant physiologic and pathophysiologic biochemical concepts.

Users will find basic and fundamental concepts that will aid students and professionals in biochemistry, medicine, and other healthcare disciplines. the text is a useful refresher that will help users meet USMLE and other professional licensing examination requirements, providing thorough introductions, key points, multicolored illustrations of chemical structures and figures, fact-filled tables, and recommended reading lists.

Автор: Sankhavaram R. Panini
Название: Medical Biochemistry - An Illustrated Review
ISBN: 1604063165 ISBN-13(EAN): 9781604063165
Издательство: Thieme Verlagsgruppe
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Цена: 44030.00 T
Наличие на складе: Поставка под заказ.
Описание:

Medical Biochemistry - An Illustrated Review - for success in the classroom and on the USMLE!

• High-yield, biochemical principles presented in a concise, easy-to-understand format with supporting summary tables
• 200+ full-color illustrations of biochemical pathways that highlight associated disorders and drug targets
• 400+ color-coded boxes that connect biochemical concepts with other basic sciences and clinical conditions
• 400 factual and USMLE-style questions with full explanations online

Автор: Smith
Название: Principles of General, Organic and Biological Chemistry
ISBN: 1259252272 ISBN-13(EAN): 9781259252273
Издательство: McGraw-Hill
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Цена: 67490.00 T
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Описание: Contributors of Volume 2: Tossi Aaron, Arnold E. Burkart, Isabel Carley, Gerald P. Dyck, Nancy Ferguson, Jane Frazee, Ruth Pollock Hamm, Maureen Kennedy, Susan Kennedy, Marcia Lunz, Joachim Matthesius, Grace Nash, Erik Nielsen, Sue Ellen Page, Martha Pline Polon, Jacobeth Postl, Pat Riello, Konnie Saliba, Miriam Samuelson, Donald Slagel, Judith Thomas, Martha Maybury WamplerBesetzung:voice, recorder and percussion

Автор: Bernard Testa
Название: Pharmacokinetic Optimization in Drug Research: Biological, Physicochemical, and Computational Strategies
ISBN: 3906390225 ISBN-13(EAN): 9783906390222
Издательство: Wiley
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Цена: 153120.00 T
Наличие на складе: Невозможна поставка.
Описание: In this age of combinatorial chemistry and high-throughput technologies, bioactive compounds called hits are discovered by the thousands. However, the road that leads from hits to lead compounds and then to pharmacokinetically optimized clinical and drug candidates is very long indeed. As a result, the screening, design, and optimization of pharmacokinetic properties has become the bottleneck and a major challenge in drug research. To shorten the time-consuming develop-ment and high rate of attrition of active compounds ultimately doomed by hidden pharmacokinetic defects, drug researchers are coming to incorporate structure-permeation, structure-distribution, structure-metabolism, and structure-toxicity relations into drug-design strategies. To this end, powerful biological, physicochemical, and computational approaches are being developed whose objectives are to increase the clinical relevance of drug design, and to eliminate as soon as possible compounds with unfavorable physicochemical properties and pharmacokinetic profiles. Toxicological issues are also of utmost importance in this paradigm. There was, hence, an urgent need for a book covering this field in an authoritative, didactic, comprehensive, factual, and conceptual manner. In this work of unique breadth and depth, international authorities and practicing experts from academia and industry present the most modern biological, physicochemical, and computational strategies to optimize gastrointestinal absorption, protein binding and distribution, brain permeation, and metabolic profile. The biological strategies emphasized in the book include cell cultures and high-throughput screens. The physicochemical strategies focus on the determination and interpretation of solubility, lipophilicity, and related molecular properties as factors and predictors of pharmacokinetic bahavior. Particular attention is paid to the lipophilicity profiles of ionized compounds, to lipophicity measurements in anisotropic media (liposomes/water, IAM columns), and to permeability across artificial membranes. Computational strategies comprise virtual screening, molecular modelling, lipophilicity, and H-bonding fields and their importance for structure-disposition relations. This book is both about theoretical and technological breakthroughs. Thus, molecular properties are contemplated from a dual perspective, namely a) their interpretation in biological and/or physicochemical terms, and b) their value in screening, lead optimization, and drug-candidate selection. In addition to its 33 chapters, the book includes a CD-ROM containing the invited lectures, oral communications and posters (in full version) presented at the Second LogP Symposium, 'Lipophilicity in Drug Disposition -- Practical and Computational Approaches to Molecular Properties Related to Drug Permeation, Disposition and Metabolism', held at the University of Lausanne in March 2000.

Автор: Lieberman, Michael A, Allan Marks
Название: Marks` Basic Medical Biochemistry, 4/e, International Edition
ISBN: 1451100035 ISBN-13(EAN): 9781451100037
Издательство: Lippincott Williams & Wilkins
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Цена: 52630.00 T
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Описание: Marks’ Basic Medical Biochemistry takes a patient-oriented approach that links biochemistry  to physiology and pathophysiology, allowing students to apply fundamental concepts to the practice of medicine—from diagnosing patients to recomm

Автор: Knoche, Herman W.
Название: Radioisotopic Methods for Biological and Medical Research (Hardback)
ISBN: 0195058062 ISBN-13(EAN): 9780195058062
Издательство: Oxford Academ
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Цена: 73920.00 T
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Описание: This is an up-to-date textbook for biologists and biomedical scientists covering the basics of radioisotope methodology and safety. Radioisotopes are widely used in biological and medical research, particularly in biochemistry. Graduate students and technicians usually learn how to use radioisotopes through short training courses or as part of laboratory courses in biology and biochemistry. This text was written for use in courses on the theoretical aspects ofradioisotopic methods or for self-study and reference; it assumes little knowledge of radioactive materials and develops mathematical discussions slowly and clearly.

Автор: Lieberman
Название: BRS Biochemistry, Molecular Biology, and Genetics, 6e
ISBN: 1451175361 ISBN-13(EAN): 9781451175363
Издательство: Lippincott Williams & Wilkins
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Цена: 36730.00 T
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Описание: BRS Biochemistry, Molecular Biology, and Genetics is an excellent aid for USMLE Step 1 preparation and for coursework in biochemistry, molecular biology, and genetics. Fully updated for its sixth edition, chapters are written in an outline format and include pedagogical features such as bolded key words, figures, tables, algorithms, and highlighted clinical correlates. USMLE-style questions and answers follow each chapter and a comprehensive exam appears at the end of the book.

Автор: Y. C. Lee
Название: Recognition of Carbohydrates in Biological Systems, Part B: Speci
ISBN: 0121822664 ISBN-13(EAN): 9780121822668
Издательство: Elsevier Science
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Цена: 151590.00 T
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Описание: Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covers the wide area of methodology of carbohydrate recognition. This volume and its companion, Volume 362, present state-of-the-art methodologies, as well as the most recent biological observations in this area.

Автор: Y. C. Lee
Название: Recognition of Carbohydrates in Biological Systems, Part A : Gene
ISBN: 0121822656 ISBN-13(EAN): 9780121822651
Издательство: Elsevier Science
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Цена: 167030.00 T
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Описание: Recognition of carbohydrates in biological systems has been gaining more and more attention in recent years. Although methodology for studying recognition has been developing, there is no volume that covs the wide area of methodology of carbohydrate recognition. This volume and its companion, Volume 363, present state-of-the-art methodologies, as well as the most recent biological observations in this area.

Автор: Sten-Knudsen
Название: Biological Membranes.2002
ISBN: 0521810183 ISBN-13(EAN): 9780521810180
Издательство: Cambridge Academ
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Цена: 140450.00 T
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Описание: This text provides a comprehensive discussion of biological mass transfer and bioelectrical phenomena. It is suitable for students in physiology, biophysics and biomedicine. Emphasis is given to the applicability of physics, physical chemistry and mathematics to the analysis of biological processes. The necessary mathematical grounding is provided.

Автор: Yeagle
Название: The Structure of Biological Membranes. 2ed. 2004
ISBN: 0849314038 ISBN-13(EAN): 9780849314032
Издательство: Taylor&Francis
Цена: 111270.00 T
Наличие на складе: Поставка под заказ.
Описание: Recent research has provided an abundance of new information on membrane biochemistry. Now more than ever, it is essential to update our current understanding of membrane structure and function to fully appreciate and apply these findings.Completely revised and updated to reflect advances in the field, The Structure of Biological Membranes, Second Edition focuses on lipids and the lipid bilayer, as well as on membrane protein structure and function, and includes a chapter on transport. It provides an integrated view of membranes as functioning units.

This new edition incorporates recent advances in membrane protein structure, membrane rafts and membrane fusion. The roles of cholesterol in the biology of cells, the structures of G-protein coupled receptors, membrane lipids as modulators of membrane-bound enzymes, and viral fusion mechanisms are presented and analyzed in depth.Updating our knowledge of biological membrane structure, this second edition serves as a valuable resource for structural biologists, biophysicists, cell biologists, biochemists, and researchers involved in the pharmaceutical industry.