Lost In Translation: Barriers To Incentives For Translational Research In Medical Sciences, Srivastava Rakesh Et Al

Автор: Martin Wehling
Название: Principles of Translational Science in Medicine
ISBN: 0128006870 ISBN-13(EAN): 9780128006870
Издательство: Elsevier Science
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Цена: 106660.00 T
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Описание: Principles of Translational Science in Medicine: From Bench to Bedside, Second Edition, provides an update on major achievements in the translation of research into medically relevant results and therapeutics. . The book presents a thorough discussion of biomarkers, early human trials, and networking models, and includes institutional and industrial support systems. It also covers algorithms that have influenced all major areas of biomedical research in recent years, resulting in an increasing numbers of new chemical/biological entities (NCEs or NBEs) as shown in FDA statistics. The book is ideal for use as a guide for biomedical scientists to establish a systematic approach to translational medicine.

Автор: Gary Hime (Editor), Helen Abud (Editor)
Название: Transcriptional and Translational Regulation of Stem Cells (Advances in Experimental Medicine and Biology)
ISBN: 9400766203 ISBN-13(EAN): 9789400766204
Издательство: Springer
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Цена: 158380.00 T
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Описание: This volume takes two approaches to this topic - (1) illustrating the general principles outlined above through a series of different stem cell examples - embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.

Автор: Robert J. Nordstrom (Editor)
Название: Translational Research In Biophotonics
ISBN: 162841068X ISBN-13(EAN): 9781628410686
Издательство: Mare Nostrum (Eurospan)
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Цена: 75770.00 T
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Описание: Translational research transforms scientific discoveries arising from laboratory, clinical, or population studies into clinical applications to reduce cancer incidence, morbidity, and mortality. Optical imaging in medicine is a rapidly growing field, showing promise for delivering new low-cost, point-of-care capabilities with dramatic increases in measurement sensitivity. Unfortunately, despite all of the promises offered by optical imaging, few concepts are making it through the translational pipeline from laboratory demonstration to commercialization for clinical use.The National Cancer Institute of the National Institutes of Health focused a research program on the study of optical imaging for translational advancement into clinical applications for reduction of cancer morbidity and mortality. This book highlights the translational activities of four research groups created for this program, called the Network for Translational Research (NTR). The research leads were Lihong Wang, Eva Sevick-Muraca, Thomas D. Wang, and Christopher Contag. While detailed insight into the nature of the research accomplished at each of these centers is provided, the purpose of this text is to demonstrate that the NTR centers with their industrial partners created significant pathways along the direction of translational research, and that these pathways can now be followed by other researchers seeking to bring these ideas closer to commercial reality. This book will be useful for academic researchers interested in taking concepts and devices beyond the usual ""proof-of-principle"" barrier into areas concerned with good laboratory practices and good manufacturing practices in order to prepare for the translation to FDA discussions.

Автор: Lyons-Weiler James
Название: Cures Vs. Profits: Successes In Translational Research
ISBN: 9814730149 ISBN-13(EAN): 9789814730143
Издательство: World Scientific Publishing
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Цена: 15840.00 T
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Описание: Did You Ever Wonder Whether Doctors Want Cures, Or Just Treatments?Did You Know ...•Grapefruit Can Interact With Over 100 Drugs, But It May Be Useful For Reducing Blood Pressure And For Weight Loss?•Adhd Over Diagnosis Is Now Recognized Widely As A Fact, And There Are Existing — And New Ways — To Avoid A Misdiagnosis?•Studies Have Been Conducted Demonstrating The Utility Of Omega 3 Fatty Acids, Meditation, Yoga, And Melatonin For Some Important Symptoms Of Adhd, Including Executive Functions?•Vaccines Have Saved Millions Of Lives In The Last Decade?•Breast Cancer Rates Are Declining In The Us, But Have Been Steadily Increasing In Japan?•Doctors Are Getting Better At Predicting Which Chemotherapy Will, And Will Not Work, On Certain Cancers?•There Are Vaccines Against Cancer?This Book Reviews Recent Key, Hard-Won Successes And Findings From Recent Biomedical Research. Written By One Of The Most Ardent Defenders Of The Public Trust In Science, It Provides An Accessible, Detailed Look At Successes In Translational Biomedical And Clinical Research. The Author Provides An Optimistic, Forward-Looking View For The Possibility Of Change For The Public Good, Cutting Through The Controversy And Gets To Very Core Of Each Topic. The Public Can Be Optimistic About The Future Of Medicine, But Only If They Learn The Facts Of These Advances, And Learn What Their Doctors Should Be Expected To Know.Highly Referenced, And Filled With Interviews From Experts And People Directly Involved In The Research Behind The New Facts In Each Chapter, This Book Is A Rich Source Of Information On Advances In Biomedicine That You Will Want To Share With Your Family & Friends.

Автор: Patterson
Название: Translational Cardiology
ISBN: 1627039341 ISBN-13(EAN): 9781627039345
Издательство: Springer
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Цена: 144410.00 T
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Описание: Covering new developments in cellular, viral and non-biological therapies, and with chapters by experts from a range of disciplines, this is an up-to-date survey of the role that circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart.

Автор: Jonathon W. Homeister; Monte S. Willis
Название: Molecular and Translational Vascular Medicine
ISBN: 162703868X ISBN-13(EAN): 9781627038683
Издательство: Springer
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Цена: 204970.00 T
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Описание: Molecular and Translational Vascular Medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine.

Автор: Robert Rhoads
Название: miRNA Regulation of the Translational Machinery
ISBN: 364226140X ISBN-13(EAN): 9783642261404
Издательство: Springer
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Цена: 153720.00 T
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Описание: This book is dedicated to understanding how miRNAs affect translation. It includes chapters representing work in plants and Caenorhabditis elegans, the biological systems that originally led to the discovery of small interfering RNAs.