Design and Analysis of Cross-Over Trials, Third Edition, Jones
Старое издание
Название: Design and Analysis of Clinical Trials with Time-to-Event Endpoints ISBN: 1420066390 ISBN-13(EAN): 9781420066395 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Provides a presentation of the design, monitoring, analysis, and interpretation of clinical trials in which time-to-event is of critical interest. This book discusses the design and monitoring of Phase II and III clinical trials with time-to-event endpoints.
Автор: Fairclough Название: Design and Analysis of Quality of Life Studies in Clinical Trials, Second Edition ISBN: 1420061178 ISBN-13(EAN): 9781420061178 Издательство: Taylor&Francis Рейтинг: Цена: 148010.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Presents a range of solutions to analytic issues. This title reflects developments in methodology with coverage of mixture models and a dataset example. It implements examples using SAS and R code and incorporates a number of examples from real QoL clinical trials to illustrate design and analysis methods.
Автор: Matsui Shigeyuki Название: Design and Analysis of Clinical Trials for Predictive Medicine ISBN: 1466558156 ISBN-13(EAN): 9781466558151 Издательство: Taylor&Francis Рейтинг: Цена: 117390.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Design and Analysis of Clinical Trials for Predictive Medicine provides statistical guidance on conducting clinical trials for predictive medicine. It covers statistical topics relevant to the main clinical research phases for developing molecular diagnostics and therapeutics--from identifying molecular biomarkers using DNA microarrays to confirming their clinical utility in randomized clinical trials.
The foundation of modern clinical trials was laid many years before modern developments in biotechnology and genomics. Drug development in many diseases is now shifting to molecularly targeted treatment. Confronted with such a major break in the evolution toward personalized or predictive medicine, the methodologies for design and analysis of clinical trials is now evolving.
This book is one of the first attempts to contribute to this evolution by laying a foundation for the use of appropriate statistical designs and methods in future clinical trials for predictive medicine. It is a useful resource for clinical biostatisticians, researchers focusing on predictive medicine, clinical investigators, translational scientists, and graduate biostatistics students.
Автор: Gerardo Ruiz Mercardo Название: Sustainability in the Design, Synthesis and Analysis of Chemical ISBN: 0128020326 ISBN-13(EAN): 9780128020326 Издательство: Elsevier Science Рейтинг: Цена: 101060.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: "
Sustainability in the Design, Synthesis and Analysis of Chemical Engineering Processes" is an edited collection of contributions from leaders in their field. It takes a holistic view of sustainability in chemical and process engineering design, and incorporates economic analysis and human dimensions. Ruiz- Mercado and Cabeza have brought to this book their experience of researching sustainable process design and life cycle sustainability evaluation to assist with development in government, industry and academia.
This book takes a practical, step-by-step approach to designing sustainable plants and processes by starting from the foundational chemical engineering fundamentals. This method enables readers to achieve new process design approaches with high influence and less complexity. It will also help you to incorporate sustainability at the early stages of project life, and build up multiple systems level perspectives. Ruiz-Mercado and Cabeza s book is the only book on the market that looks at process sustainability from a chemical engineering fundamentals perspective. Improve plants, processes, and products with sustainability in mind; from conceptual design to life cycle assessmentIllustrates how to avoid retro fitting costs by planning for sustainability concerns at the start of the design processLinks sustainability to chemical engineering fundamentalsIncorporates economic analysis and human dimensions for a holistic view of sustainability in chemical and process engineering design"
Автор: Jhuma Sadhukhan,Kok Siew Ng,Elias Martinez Hernand Название: Biorefineries and Chemical Processes: Design, Integration and Sustainability Analysis ISBN: 1119990866 ISBN-13(EAN): 9781119990864 Издательство: Wiley Рейтинг: Цена: 93930.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: As the range of feedstocks, process technologies and products expand, biorefineries will become increasingly complex manufacturing systems. This book presents process modelling and integration, and whole system life cycle analysis tools for the synthesis, design, operation and sustainable development of biorefinery and chemical processes.
State-of-the-Art Methods for Drug Safety Assessment
Responding to the increased scrutiny of drug safety in recent years, Quantitative Evaluation of Safety in Drug Development: Design, Analysis and Reporting explains design, monitoring, analysis, and reporting issues for both clinical trials and observational studies in biopharmaceutical product development. It presents the latest statistical methods for drug safety assessment.
The book's three sections focus on study design, safety monitoring, and data evaluation/analysis. The book addresses key challenges across regulatory agencies, industry, and academia. It discusses quantitative approaches to safety evaluation and risk management in drug development, covering Bayesian methods, effective safety graphics, and risk-benefit evaluation.
Written by a team of experienced leaders, this book brings the most advanced knowledge and statistical methods of drug safety to the statistical, clinical, and safety community. It shares best practices and stimulates further research and methodology development in the drug safety area.
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