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Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases, Barbara Stefanska; David J. MacEwan


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Автор: Barbara Stefanska; David J. MacEwan
Название:  Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases
ISBN: 9781493967414
Издательство: Springer
Классификация:


ISBN-10: 149396741X
Обложка/Формат: Hardback
Страницы: 197
Вес: 0.60 кг.
Дата издания: 2017
Серия: Methods in pharmacology and toxicology
Язык: English
Издание: 1st ed. 2017
Иллюстрации: 22 illustrations, color; 16 illustrations, black and white; xii, 197 p. 38 illus., 22 illus. in color.
Размер: 185 x 266 x 21
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Германии
Описание: This practical collection examines methodologies originating from the benefits of genome-wide approaches to studying epigenetics, which has opened the emerging field of epigenomics. Focusing on the areas of cancer, inflammatory and autoimmune disorders, chapters discuss three main components of the epigenome and their role in the regulation of gene expression and present a detailed method section specific to studying each component, including data analyses, troubleshooting, and feasibility in different experimental settings. The main topics are high-throughput and targeted methods for DNA methylation analysis, nucleosome position mapping, studying epigenetic effects of gut microbiota, optical imaging for detection of epigenetic aberrations in living cells, methods for microRNA, and histone code profiling. Written for the Methods in Pharmacology and Toxicology series, the book includes the kind of detail and implementation advice to encourage success in the lab.
Authoritative and easily applicable, Epigenetics and Gene Expression in Cancer, Inflammatory and Immune Diseases aims to provide pharmacologists, molecular biologists, bioinformaticians, and toxicologists with a vital background on epigenetics and state-of-the-art techniques in epigenomics.

Дополнительное описание: High-Throughput Techniques for DNA Methylation Profiling.- Reduced Representation Bisulfite Sequencing (RRBS) and Cell Sorting Prior to DNA Methylation Analysis in Psychiatric Disorders.- Targeted DNA Methylation Analysis Methods.- Analyzing Targeted Nucl


The Immune System

Автор: Peter Parham
Название: The Immune System
ISBN: 0815341466 ISBN-13(EAN): 9780815341468
Издательство: Taylor&Francis
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Цена: 46960.00 T
Наличие на складе: Невозможна поставка.
Описание: "The Immune System, Third Edition" is designed for use in immunology courses for undergraduate, medical, dental, and pharmacy students. This class-tested and proven textbook synthesizes the established facts of immunology into a comprehensible, coherent, and up-to-date account of how the human immune system works and the effects it has on the health and survival of individuals and populations, making generous use of medical examples to illustrate points. The reader-friendly text, full-color illustrations, and section and chapter summaries make the book accessible and easily understandable to students.

The Third Edition is a major revision and includes two new chapters: Innate Immunity (Chapter 2) and Principles of Adaptive Immunity (Chapter 3). Former Chapter 12 has been divided into three chapters: vaccination (Chapter 14), transplantation (Chapter 15), and cancer (Chapter 16). The number of end-of-chapter questions has been expanded and now include essay, multiple choice, and case study (USMLE-format) questions with answers provided at the end of the book.

"The Immune System" is adapted from "Immunobiology" by Janeway, Travers, and Walport.

Inflammatory and Autoimmune Disorders of the Nervous System in Children

Автор: Dale
Название: Inflammatory and Autoimmune Disorders of the Nervous System in Children
ISBN: 1898683662 ISBN-13(EAN): 9781898683667
Издательство: Wiley
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Цена: 137280.00 T
Наличие на складе: Поставка под заказ.
Описание: Inflammatory disorders of the nervous system, although individually uncommon, collectively make up 10-20% of acute paediatric neurology presentations and many are potentially treatable Provides a detailed and comprehensive summary of the childhood diseases that are caused by the immune system and their treatments .

Inflammatory cardiomyopathy (dcmi) - pathogenesis and therapy

Автор: Heinz-Peter Schulthei?; Michel Noutsias (Eds.)
Название: Inflammatory cardiomyopathy (dcmi) - pathogenesis and therapy
ISBN: 3764383518 ISBN-13(EAN): 9783764383510
Издательство: Springer
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Цена: 204040.00 T
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Описание: Cardiomyopathy (CM) is one of the most frequent causes of heart failure. There are many different causes of the disease, therefore many different kinds of cardiomyopathies exist. This work focuses on inflammatory CM, belonging to the Dilated Cardiomyopathies (DCMi). It covers epidemiology, pathology, immunology, diagnosis and treatment strategies.

Gene Therapy for Autoimmune and Inflammatory Diseases

Автор: Yuti Chernajovsky; Paul D. Robbins
Название: Gene Therapy for Autoimmune and Inflammatory Diseases
ISBN: 3034803060 ISBN-13(EAN): 9783034803069
Издательство: Springer
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Цена: 174130.00 T
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Описание: This text addresses the latest advances in viral and non-viral vectors as well as novel targets and methods for the treatment of autoimmune and inflammatory disease. Its main focus is on pre-clinical testing with up-to-date clinical trials.

Clinical Therapy Research in the Inflammatory Diseases

Автор: Vollenhoven Ronald Van
Название: Clinical Therapy Research in the Inflammatory Diseases
ISBN: 9814656321 ISBN-13(EAN): 9789814656320
Издательство: World Scientific Publishing
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Цена: 74970.00 T
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Описание: This unique textbook provides information on the dramatic advances taking place in the field of inflammatory (autoimmune) diseases and their therapies.

Compendium of Inflammatory Diseases

Автор: Parnham
Название: Compendium of Inflammatory Diseases
ISBN: 3764385308 ISBN-13(EAN): 9783764385309
Издательство: Springer
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Цена: 931690.00 T
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Описание: Inflammation has become one of the most exciting and rewarding areas of medical research. Recent years have seen a revolution in our understanding of how blood and tissue cells interact and of the intracellular mechanisms controlling their activation. This has revealed the underlying inflammatory pathology of many diseases and provided multiple new targets for anti-inflammatory and immunomodulatory therapy. The Encyclopedia of Inflammatory Diseases will cover the following areas: * Inflammatory Processes and Cells * Inflammatory Diseases * Mediators of Inflammation * Pharmacology of Inflammation Since inflammatory diseases and their therapy cover a broad range of scientific and medical fields, the encyclopedia will be co-edited by four international experts, a clinician and three researchers from the disciplines of immunology, biochemistry, and pharmacology, in this way providing students, basic and clinical scientists and practitioners in academia, hospitals and industry with valuable interlinked information. This living project will serve as a reliable and comprehensive data pool for everybody working in inflammation research. Owing to its dynamic nature, it will grow with time and future editions, becoming an indispensible source of information for academia, clinical practitioners and industry.

The Origin of Chronic Inflammatory Systemic Diseases and their Se

Автор: Rainer Straub
Название: The Origin of Chronic Inflammatory Systemic Diseases and their Se
ISBN: 0128033215 ISBN-13(EAN): 9780128033210
Издательство: Elsevier Science
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Цена: 114530.00 T
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Описание:

Chronic inflammatory diseases such as rheumatoid arthritis, ankylosing spondylitis, multiple sclerosis, inflammatory bowel diseases, and others typically stimulate a systemic response of the entire body. This response has a uniform character in many diseases because common pathways are switched on. The uniform response regulates systemic energy and water provision. However, long-term application of this program leads to typical disease sequelae such as fatigue / depressive symptoms, sleep disturbances, anorexia, malnutrition, muscle wasting - cachexia, cachectic obesity, insulin resistance, dyslipidemia, alterations of steroid hormone axes, disturbances of the hypothalamic-pituitary-gonadal axis, elevated sympathetic tone, hypertension, volume expansion, decreased parasympathetic tone, inflammation-related anemia, bone loss, hypercoagulability, circadian rhythms of symptoms, and disease exacerbation by stress .

The Origin of Chronic Inflammatory Systemic Diseases and Their Sequelae demonstrates concepts of neuroendocrine immunology, energy and water regulation, and evolutionary medicine in order to show that the uniform response that regulates systemic energy and water provision, has been positively selected for acute physiological responses and short-lived disease states, but is a misguided program in chronic inflammatory diseases and aging.


Anti-inflammatory Nutraceuticals and Chronic Diseases

Автор: Gupta
Название: Anti-inflammatory Nutraceuticals and Chronic Diseases
ISBN: 3319413325 ISBN-13(EAN): 9783319413327
Издательство: Springer
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Цена: 167700.00 T
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Описание: This comprehensive volume focuses on anti-inflammatory nutraceuticals and their role in various chronic diseases. Food and Drug Administration (FDA) approved drugs such as steroids, non-steroidal anti-inflammatory drugs (NSAIDS), statins and metformin have been shown to modulate inflammatory pathways, but their long-term intake has been associated with numerous side effects. This means that there is enormous potential for dietary agents that can modulate inflammatory pathways in humans. Leading experts describe the latest research on the role of anti-inflammatory nutraceuticals in preventing and treating chronic diseases.

Epigenetics, Energy Balance, and Cancer

Автор: Berger
Название: Epigenetics, Energy Balance, and Cancer
ISBN: 3319416081 ISBN-13(EAN): 9783319416083
Издательство: Springer
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Цена: 156720.00 T
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Описание: This volume of Energy Balance and Cancer provides state-of-the-art descriptions of the rapidly evolving science of epigenetics and how it may explain mechanisms by which alterations in energy balance such as obesity and physical activity may impact cancer. In addition to chapters explaining the processes mediating epigenetic regulation, the volume contains a series of chapters explaining how environmental influences including early life events, nutrition, exercise and microbiota may induce epigenetic changes that can affect carcinogenesis. The following chapters describe epigenetic relations of energy balance to cancer in distinct organ systems including esophagus, colon, prostate and breast. Epigenetics, Energy Balance and Cancer provides a valuable resource for students, research investigators and clinicians seeking to better understand these processes as well as a basis for novel translational and transdisciplinary approaches to further elucidate these processes and develop preventive and therapeutic strategies.

Immune and Inflammatory Responces in Nervous System.2002

Автор: Rothwell
Название: Immune and Inflammatory Responces in Nervous System.2002
ISBN: 0198509804 ISBN-13(EAN): 9780198509806
Издательство: Oxford Academ
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Цена: 248160.00 T
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Описание: This new edition covers recent advances in understanding immunological and inflammatory responses in the nervous system. This research is driven by the potential to use knowledge of the molecules and mechanisms involved to intervene in, and arrest, neurodegenerative disease processes. Throughout, the emphasis is on the opportunities and ideas for novel treatments.


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