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New Approaches of Protein Function Prediction from Protein Intera, Hou, Jingyu


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Цена: 78040.00T
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Автор: Hou, Jingyu
Название:  New Approaches of Protein Function Prediction from Protein Intera
ISBN: 9780128098141
Издательство: Elsevier Science
Классификация:
ISBN-10: 0128098147
Обложка/Формат: Paperback
Страницы: 124
Вес: 0.22 кг.
Дата издания: 11.01.2017
Язык: English
Размер: 154 x 250 x 13
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

New Approaches of Protein Function Prediction from Protein Interaction Networks contains the critical aspects of PPI network based protein function prediction, including semantically assessing the reliability of PPI data, measuring the functional similarity between proteins, dynamically selecting prediction domains, predicting functions, and establishing corresponding prediction frameworks.

Functional annotation of proteins is vital to biological and clinical research and other applications due to the important roles proteins play in various biological processes. Although the functions of some proteins have been annotated via biological experiments, there are still many proteins whose functions are yet to be annotated due to the limitations of existing methods and the high cost of experiments. To overcome experimental limitations, this book helps users understand the computational approaches that have been rapidly developed for protein function prediction.



Protein Structure Prediction: Concepts and Applications

Автор: Anna Tramontano
Название: Protein Structure Prediction: Concepts and Applications
ISBN: 352731167X ISBN-13(EAN): 9783527311675
Издательство: Wiley
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Цена: 73870.00 T
Наличие на складе: Невозможна поставка.
Описание: While most textbooks on bioinformatics focus on genetic algorithms and treat protein structure prediction only superficially, this course book assumes a novel and unique focus. Adopting a didactic approach, the author explains all the current methods in terms of their reliability, limitations and user-friendliness.

Prediction of Protein Secondary Structure

Автор: Yaoqi Zhou; Andrzej Kloczkowski; Eshel Faraggi; Yu
Название: Prediction of Protein Secondary Structure
ISBN: 1493964046 ISBN-13(EAN): 9781493964048
Издательство: Springer
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Цена: 139750.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This thorough volume explores predicting one-dimensional functional properties, functional sites in particular, from protein sequences, an area which is getting more and more attention. Beginning with secondary structure prediction based on sequence only, the book continues by exploring secondary structure prediction based on evolution information, prediction of solvent accessible surface areas and backbone torsion angles, model building, global structural properties, functional properties, as well as visualizing interior and protruding regions in proteins. Written for the highly successful Methods in Molecular Biology series, the chapters include the kind of detail and implementation advice to ensure success in the laboratory.

Practical and authoritative, Prediction of Protein Secondary Structure serves as a vital guide to numerous state-of-the-art techniques that are useful for computational and experimental biologists.

Computational Approaches To Protein

Автор: Fuxreiter
Название: Computational Approaches To Protein
ISBN: 1466561572 ISBN-13(EAN): 9781466561571
Издательство: Taylor&Francis
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Цена: 209270.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

The Latest Developments on the Role of Dynamics in Protein Functions

Computational Approaches to Protein Dynamics: From Quantum to Coarse-Grained Methods presents modern biomolecular computational techniques that address protein flexibility/dynamics at all levels of theory. An international contingent of leading researchers in chemistry, physics, and biology show how these advanced methods provide insights into dynamic aspects of biochemical processes. A particular focus is on intrinsically disordered proteins (IDPs), which lack a well-defined three-dimensional structure and function as dynamic ensembles.

The book covers a wide spectrum of dynamics, from electronic structure-based to coarse-grained techniques via multiscaling at different levels. After an introduction to dynamics and historical overview of basic methodologies, the book addresses the following issues:

  • Is there a quantitative relationship between enzymatic catalysis and protein dynamics?
  • Which are the functionally relevant motions of proteins?
  • How can structural properties and partner recognition mechanisms of IDPs be simulated?
  • How can we speed up molecular dynamics?
  • How can we describe conformational ensembles by the synergistic effort of computations and experiments?

While dynamics is now considered essential for interpreting protein action, it is not yet an integral component in establishing structure-function relationships of proteins. Helping to reshape this classical view in biochemistry, this groundbreaking book explores advances in computational methodology and contributes to the new, ensemble way of studying proteins.



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