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It`s in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging, Rosenberg, Eugene


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Автор: Rosenberg, Eugene
Название:  It`s in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging
Перевод названия: Эжен Розенберг: Это заложено в твоей ДНК
ISBN: 9780128125021
Издательство: Elsevier Science
Классификация:





ISBN-10: 0128125020
Обложка/Формат: Paperback
Страницы: 266
Вес: 0.36 кг.
Дата издания: 13.04.2017
Язык: English
Размер: 151 x 228 x 18
Читательская аудитория: Professional & vocational
Подзаголовок: From discovery to structure, function and role in evolution, cancer and aging
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Its in Your DNA: From Discovery to Structure, Function and Role in Evolution, Cancer and Aging describes, in a clear, approachable manner, the progression of the experiments that eventually led to our current understanding of DNA. This fascinating work tells the whole story from the discovery of DNA and its structure, how it replicates, codes for proteins, and our current ability to analyze and manipulate it in genetic engineering to begin to understand the central role of DNA in evolution, cancer, and aging.

While telling the scientific story of DNA, this captivating treatise is further enhanced by brief sketches of the colorful lives and personalities of the key scientists and pioneers of DNA research. Major discoveries by Meischer, Darwin, and Mendel and their impacts are discussed, including the merging of the disciplines of genetics, evolutionary biology, and nucleic acid biochemistry, giving rise to molecular genetics.

After tracing development of the gene concept, critical experiments are described and a new biological paradigm, the hologenome concept of evolution, is introduced and described. The final two chapters of the work focus on DNA as it relates to cancer and gerontology.

This book provides readers with much-needed knowledge to help advance their understanding of the subject and stimulate further research. It will appeal to researchers, students, and others with diverse backgrounds within or beyond the life sciences, including those in biochemistry, genetics/molecular genetics, evolutionary biology, epidemiology, oncology, gerontology, cell biology, microbiology, and anyone interested in these mechanisms in life.

  • Highlights the importance of DNA research to science and medicine
  • Explains in a simple but scientifically correct manner the key experiments and concepts that led to the current knowledge of what DNA is, how it works, and the increasing impact it has on our lives
  • Emphasizes the observations and reasoning behind each novel idea and the critical experiments that were performed to test them


DNA Repair of Cancer Stem Cells

Автор: Mathews
Название: DNA Repair of Cancer Stem Cells
ISBN: 9400745893 ISBN-13(EAN): 9789400745896
Издательство: Springer
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Цена: 148020.00 T
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Описание: The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.

Gastroenteropancreatic System and Its Tumors: Part I, An Issue of Endocrinology Clinics,39-4

Автор: Aaron I. Vinik
Название: Gastroenteropancreatic System and Its Tumors: Part I, An Issue of Endocrinology Clinics,39-4
ISBN: 1437724477 ISBN-13(EAN): 9781437724479
Издательство: Elsevier Science
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Цена: 80560.00 T
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Описание: Offers information about tumors of the gastroenteropancreatic system. This title covers such topics as: the history and development of the gastroenteropancreatic endocrine axis; the changing face and epidemiology of neuroendocrine tumors (NETs); and, chromogranins current state of the art, pathology of gastroenteropancreatic (GEP) disorders.


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