International Science Between the World Wars: The Case of Genetics, Krementsov Nikolai
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 64300.00 T Наличие на складе: Нет в наличии. Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
The (printed) 'Updated Edition' now comes with added value access to the complete, downloadable eBook version via Student Consult. Search, read and revise whilst on the move and use the interactive self-assessment to test your understanding. Crash Course - a more flexible, practical learning package than ever before.
Crash Course - your effective everyday study companion PLUS the perfect antidote for exam stress Save time and be assured you have all the core information you need in one place to excel on your course and achieve exam success.
A winning formula now for over 15 years, each series volume has been fine-tuned and fully updated, with an improved layout tailored to make your life easier. Specially written by senior medical students or recent graduates - those who have just been in the exam situation - with all information thoroughly checked and quality assured by expert faculty advisors, the result is books which exactly meet your needs and you know you can trust.
The subject of cell biology and genetics has never been more essential to the medical curriculum and to modern medicine - yet is widely feared by students. This fully revised edition aims to make it as easy to understand and remember as possible, to ensure a solid grounding in the essential underlying principles and how they relate to clinical practice. It incorporates the latest developments in this fascinating and fast-moving field - including the human genome project and spin-offs such as the thousand genome project - as well as discussion of important ethical issues. Emerging molecular tools and laboratory techniques are explained so that you can appreciate where new treatments for genetic disease and screening technologies have arisen. An updated self-assessment section matching the latest exam formats then allows you to assess your progress and test your performance.
More than 180 illustrations present clinical, diagnostic and practical information in an easy-to-follow manner
Friendly and accessible approach to the subject makes learning especially easy
Written by students for students - authors who understand exam pressures
Contains 'Hints and Tips' boxes, and other useful aide-m moires
Succinct coverage of the subject enables 'sharp focus' and efficient use of time during exam preparation
Contains a fully updated self-assessment section - ideal for honing exam skills and self-testing
Self-assessment section fully updated to reflect current exam requirements
Contains 'common exam pitfalls' as advised by faculty
Crash Courses also available electronically
Online self-assessment bank also available - content edited by Dan Horton-Szar
The (printed) 'Updated Edition' now comes with added value access to the complete, downloadable eBook version via Student Consult. Search, read and revise whilst on the move and use the interactive self-assessment to test your understanding. Crash Course - a more flexible, practical learning package than ever before.
Now celebrating over 10 years of success - Crash Course has been specially devised to help you get through your exams with ease.
Completely revised throughout, the new edition of Crash Course is perfectly tailored to meet your needs by providing everything you need to know in one place. Clearly presented in a tried and trusted, easy-to-use, format, each book in the series gives complete coverage of the subject in a no-nonsense, user-friendly fashion.
Commencing with 'Learning Objectives', each chapter guides you succinctly through the topic, giving full coverage of the curriculum whilst avoiding unnecessary and often confusing detail. Each chapter is also supported by a full artwork programme, and features the ever popular 'Hints and Tips' boxes as well as other useful aide-m moires. A
Автор: Michael Lynch and Bruce Walsh Название: Genetics and Analysis of Quantitative Traits ISBN: 0878934812 ISBN-13(EAN): 9780878934812 Издательство: Oxford Academ Рейтинг: Цена: 344850.00 T Наличие на складе: Ожидается поступление. Описание: Professors Lynch and Walsh bring together the diverse array of theoretical and empirical applications of quantitative genetics in a work that is up-to-date, comprehensive and accessible to anyone with a rudimentary understanding of statistics and genetics.
Автор: Wilkins Ralph G. Название: Animal Genetics for Chemists ISBN: 178262760X ISBN-13(EAN): 9781782627609 Издательство: Royal Society of Chemistry Рейтинг: Цена: 49270.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Setting out to cover the fundamentals of the subject, this book features humans, other mammals and occasionally other animals to illustrate principles.
Автор: Streips Название: Modern Microbiology & Genetics.2002 ISBN: 0471386650 ISBN-13(EAN): 9780471386650 Издательство: Wiley Рейтинг: Цена: 203810.00 T Наличие на складе: Поставка под заказ. Описание: In accordance with its predecessor, the completely revised and expanded Second Edition of Modern Microbial Genetics focuses on how bacteria and bacteriophage arrange and rearrange their genetic material through mutation, evolution, and genetic exchange to take optimal advantage of their environment. The text is divided into three sections: DNA Metabolism, Genetic Response, and Genetic Exchange. The first addresses how DNA replicates, repairs itself, and recombines, as well as how it may be manipulated. The second section is devoted to how microorganisms interact with their environment, including chapters on sporulation and stress shock, and the final section contains the latest information on classic exchange mechanisms such as transformation and conjugation. Chapters include: * Gene Expression and Its Regulation * Single-Stranded DNA Phages * Genetic Tools for Dissecting Motility and Development of Myxococcus xanthus * Molecular Mechanism of Quorum Sensing * Transduction in Gram-Negative Bacteria * Genetic Approaches in Bacteria with No Natural Genetic Systems The editors also cultivate an attention to global regulatory systems throughout the book, elucidating how certain genes and operons in bacteria, defined as regulons, network and cooperate to suit the needs of the bacterial cell. With clear appreciation for the impact of molecular genomics, this completely revised and updated edition proves that Modern Microbial Genetics remains the benchmark text in its field.
Автор: Michael T. Compton and Marc Manseau Название: The Complex connection between cannabis and schizophrenia ISBN: 0128047917 ISBN-13(EAN): 9780128047910 Издательство: Elsevier Science Рейтинг: Цена: 70690.00 T Наличие на складе: Поставка под заказ. Описание:
The Complex Connections between Cannabis and Schizophrenia provides an in-depth overview of the current state of research into the role that cannabis plays in schizophrenia, covering both the pathophysiological and the pharmacological implications. It addresses the epidemiology of cannabis use and the risks associated with its use, the biological aspects of the drug, its effects on the brain and the pharmacological possibilities of using cannabidiol to treat schizophrenia.
It is the only book on the market devoted exclusively to examining the links between this very commonly used (and misused) drug and a specific set of devastating psychiatric illnesses, providing a comprehensive guide to our current understandings of this relationship.
Marijuana is the most commonly used illicit drug globally, and is becoming increasingly decriminalized and even legalized worldwide. Among the numerous mental-health concerns related to the drug, there is mounting evidence of an intricate link between cannabis use and schizophrenia and related psychotic disorders. At the same time, there is promising evidence to suggest that cannabidiol, one of the many compounds found in cannabis that activates the brain's cannabinoid receptors, could prove to be an effective antipsychotic to treat schizophrenia.
Synthesizes existing knowledge about the confusing, but crucial, relationship between cannabis use and schizophrenia symptoms
Provides a comprehensive overview of the neurobiological mechanisms of cannabis use and its effects on the brain, including an exploration of the endocannabinoid system
Examines the promising evidence suggesting cannabidiol as an effective antipsychotic treatment for schizophrenia
Aids readers studying the neurobiological underpinning of cannabis addiction and psychosis in determining directions for their own future research
Автор: J.H. Gillespie Название: Population genetics: a concise guide ISBN: 0801880092 ISBN-13(EAN): 9780801880094 Издательство: Wiley Рейтинг: Цена: 34850.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is indispensable for students working in a laboratory setting or studying free-ranging populations.
Автор: Pierce Benjamin A Название: Genetics Essentials. Concepts and Connections. - 3th ed. ISBN: 1464190755 ISBN-13(EAN): 9781464190759 Издательство: Springer Рейтинг: Цена: 60550.00 T Наличие на складе: Поставка под заказ. Описание: Derived from Ben Pierce's popular and acclaimed Genetics: A Conceptual Approach, this streamlined text covers basic transmission, molecular, and population genetics.
Автор: Sall, T. Bengt O. Bengtsson Название: Understanding Population Genetics ISBN: 1119124034 ISBN-13(EAN): 9781119124030 Издательство: Wiley Рейтинг: Цена: 54860.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: An inspiring introduction to a vital scientific field. The reader is taken through ten mathematical derivations that lead to important results, explaining in a hands-on manner the key concepts and methods of theoretical population genetics. The derivations are carefully worked out and easy to follow.
Автор: Wailoo Keith, Nelson Alondra, Lee Catherine Название: Genetics and the Unsettled Past: The Collision Between DNA, Race, and History ISBN: 0813552559 ISBN-13(EAN): 9780813552552 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 30490.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: <p>Our genetic markers have come to be regarded as portals to the past. Analysis of these markers is increasingly used to tell the story of human migration; to investigate and judge issues of social membership and kinship; to rewrite history and collective memory; to right past wrongs and to arbitrate legal claims and human rights controversies; and to open new thinking about health and well-being. At the same time, in many societies genetic evidence is being called upon to repair the racial past and to transform scholarly and popular opinion about the “nature” of identity in the present. </p> <p><em>Genetics and the Unsettled Past</em> considers the alignment of genetic science with commercial genealogy, with legal and forensic developments, and with pharmaceutical innovation to examine how these trends lend renewed authority to biological understandings of race and history. </p> <p>This unique collection brings together scholars from a wide range of disciplines to explore the emerging and often contested connections among race, DNA, and history. Written for a general audience, the book’s essays touch upon a variety of topics, including the rise and implications of DNA in genealogy, law, and other fields; the cultural and political uses and misuses of genetic information; the way in which DNA testing is reshaping understandings of group identity for French Canadians, native Americans, south Africans, and many others within and across cultural and national boundaries; and the sweeping implications of genetics for society today.</p>
This title includes a number of Open Access chapters.
This important book explores recent research by experts in the field pertaining to the role played by genetic factors in human pathology. A range of perspectives creates a well-rounded picture, including:
host-pathogen interactions
causal relationships between genes and the environment
the effects of environmental chemicals on gene expression
DNA methylation
The book also covers the analysis and provides models for understanding the epigenetics-pathology connection.
This book is designed for use by senior undergraduate and graduate students from several disciplines such as general, molecular, cellular biology, genetics, genomics, proteomics, and bioinformatics. It will also serve as a reference book for existing researchers and new investigators entering this rather unexplored field.
Название: Applying Pharmacogenomics in Therapeutics ISBN: 1466582677 ISBN-13(EAN): 9781466582675 Издательство: Taylor&Francis Рейтинг: Цена: 183750.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Recent advances in high-throughput gene sequencing and other omics biotechnologies have served as a springboard for the field of pharmacogenomics. Pharmacogenomics is now generally accepted as the major determinant of variable drug safety, efficacy, and cost-effectiveness. Therefore, widespread use of pharmacogenomics for patient care has become a critical requirement. There is an unprecedented urgency for aspiring and practicing clinicians to become trained on how to interpret data from pharmacogenomic testing in preparation for the future of healthcare--i.e., personalized medicine.
Applying Pharmacogenomics in Therapeutics provides timely coverage of the principles, practice, and potential of pharmacogenomics and personalized medicine. Comprised of chapters contributed by well-established pharmacologists and scientists from US and Chinese academia and industry, this authoritative text:
Demonstrates how to apply the principles of pharmacogenomics and its biotechnologies in patient care
Depicts the use of genetic biomarkers in drug discovery and development, laboratory medicine, and clinical services
Describes the practice of pharmacogenomics in the treatment of cancers, cardiovascular diseases, neurologic and psychiatric disorders, and pulmonary diseases
Discusses the merging of pharmacogenomics and alternative medicine, as well as the integration of pharmacogenomics into pharmacoeconomics
Each chapter begins with the key concepts, followed by in-depth explorations of case reports or critical evaluations of genetic variants/biomarkers, and concludes with questions for self-examination.
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