Drug Transporters: Role and Importance in Adme and Drug Development Complete Set 9781782628675

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Автор: Nicholls Glynis, Youdim Kuresh, Fox David
Название: Drug Transporters: Role and Importance in Adme and Drug Development Complete Set
ISBN: 9781782628675
Издательство: Royal Society of Chemistry
Классификация:

Биохимия

Технологии производства фармацевтических препаратов

ISBN-10: 1782628673
Обложка/Формат: Hardback
Страницы: 870
Вес: 1.40 кг.
Дата издания: 07.09.2016
Серия: Drug discovery
Язык: English
Иллюстрации: No
Размер: 165 x 249 x 47
Читательская аудитория: Professional and scholarly
Ключевые слова: Proteins,Molecular biology, SCIENCE / Life Sciences / Biochemistry,SCIENCE / Life Sciences / Molecular Biology
Подзаголовок: Role and importance in adme and drug development complete set
Рейтинг:
Поставляется из: Англии
Описание: Understanding and quantifying the effects of membrane transporters within the human body is essential for modulating drug safety and drug efficacy. This two volume set of books comprehensively reviews current knowledge and techniques in the transporter sciences and their relations to drug metabolism and pharmacokinetics. The second volume is specifically dedicated to emerging science and technologies, highlighting potential areas for future advances within the drug transporter field. The topics covered in this set of books ensure that all relevant aspects of transporters are described across the drug development process, from in silico models and preclinical tools through to the potential impact of transporters in the clinic. Contributions are included from expert leaders in the field, at-the-bench industrial scientists, renowned academics and international regulators. Case studies and emerging developments are highlighted, together with the merits and limitations of the available methods and tools, and extensive references to reviews on specific in-depth topics are also included for those wishing to pursue their knowledge further. As such, this text serves as an essential handbook of information for postgraduate students, academics, industrial scientists and regulators who wish to understand the role of transporters in absorption, distribution, metabolism, and excretion processes. In addition, it is also a useful reference tool on the models and calculations necessary to predict their effect on human pharmacokinetics and pharmacodynamics.

Drug Transporters: Role and Importance in Adme and Drug Development Complete Set, Nicholls Glynis, Youdim Kuresh, Fox David