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DNA Repair in Cancer Therapy, Kelley, Mark R.


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Цена: 124640.00T
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Ориентировочная дата поставки: Август-начало Сентября
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Автор: Kelley, Mark R.
Название:  DNA Repair in Cancer Therapy
ISBN: 9780128035825
Издательство: Elsevier Science
Классификация:
ISBN-10: 012803582X
Обложка/Формат: Hardback
Страницы: 416
Вес: 1.14 кг.
Дата издания: 08.09.2011
Язык: English
Издание: 2 ed
Размер: 200 x 260 x 28
Подзаголовок: Molecular targets and clinical applications
Ссылка на Издательство: Link
Рейтинг:
Поставляется из: Европейский союз
Описание:

DNA Repair and Cancer Therapy: Molecular Targets and Clinical Applications, Second Edition provides a comprehensive and timely reference that focuses on the translational and clinical use of DNA repair as a target area for the development of diagnostic biomarkers and the enhancement of cancer treatment.

Experts on DNA repair proteins from all areas of cancer biology research take readers from bench research to new therapeutic approaches. This book provides a detailed discussion of combination therapies, in other words, how the inhibition of repair pathways can be coupled with chemotherapy, radiation, or DNA damaging drugs.

Newer areas in this edition include the role of DNA repair in chemotherapy induced peripheral neuropathy, radiation DNA damage, Fanconi anemia cross-link repair, translesion DNA polymerases, BRCA1-BRCA2 pathway for HR and synthetic lethality, and mechanisms of resistance to clinical PARP inhibitors.



Principles and Practice of Radiation Therapy

Автор: Charles M. Washington
Название: Principles and Practice of Radiation Therapy
ISBN: 0323287522 ISBN-13(EAN): 9780323287524
Издательство: Elsevier Science
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Цена: 208290.00 T
Наличие на складе: Невозможна поставка.
Описание:

The only radiation therapy text written by radiation therapists, Principles and Practice of Radiation Therapy, 4th Edition helps you understand cancer management and improve clinical techniques for delivering doses of radiation. A problem-based approach makes it easy to apply principles to treatment planning and delivery. New to this edition are updates on current equipment, procedures, and treatment planning. Written by radiation therapy experts Charles Washington and Dennis Leaver, this comprehensive text will be useful throughout your radiation therapy courses and beyond.

  • Comprehensive coverage of radiation therapy includes a clear introduction and overview plus complete information on physics, simulation, and treatment planning.
  • Spotlights and shaded boxes identify the most important concepts.
  • End-of-chapter questions provide a useful review.
  • Chapter objectives, key terms, outlines, and summaries make it easier to prioritize, understand, and retain key information.
  • Key terms are bolded and defined at first mention in the text, and included in the glossary for easy reference.
  • UPDATED chemotherapy section, expansion of What Causes Cancer, and inclusions of additional cancer biology terms and principles provide the essential information needed for clinical success.
  • UPDATED coverage of post-image manipulation techniques includes new material on Cone beam utilization, MR imaging, image guided therapy, and kV imaging.
  • NEW section on radiation safety and misadministration of treatment beams addresses the most up-to-date practice requirements.
  • Content updates also include new ASRT Practice Standards and AHA Patient Care Partnership Standards, keeping you current with practice requirements.
  • UPDATED full-color insert is expanded to 32 pages, and displays images from newer modalities.

DNA Repair of Cancer Stem Cells

Автор: Mathews
Название: DNA Repair of Cancer Stem Cells
ISBN: 9400745893 ISBN-13(EAN): 9789400745896
Издательство: Springer
Рейтинг:
Цена: 148020.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: The existence of ‘cancer stem cells’ (CSCs) has been a topic of heated debate for the last few years within the field of cancer biology. Their continuous characterization in a variety of solid tumors has lead to an abundance of evidence supporting their existence. CSCs are believed to be responsible for resistance against conventional treatment regimes of chemotherapy and radiation, ultimately, leading to metastasis and patient demise. To help aid clinicians, pharmaceutical companies and academic labs investigating how to better kill these highly aggressive cells we have summarized the DNA repair mechanism(s) and their role in the maintenance and regulation of both normal and cancer stem cells. Our book represents a comprehensive investigation into the highly effective DNA repair mechanisms of CSCs and what we need to understand in order to develop more advanced therapies to eradicate them from patients. Currently, there are no other published works entirely on DNA repair and Cancer Stem Cells. In addition, our book provides a comprehensive overview of CSC isolation and characterization from a variety of solid tumor types.

Drug Delivery Systems In Cancer Therapy

Автор: Brown, Dennis M.
Название: Drug Delivery Systems In Cancer Therapy
ISBN: 0896038882 ISBN-13(EAN): 9780896038882
Издательство: Springer
Рейтинг:
Цена: 200260.00 T
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Описание: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.

Gene Therapy of Cancer,

Автор: Edmund C. Lattime
Название: Gene Therapy of Cancer,
ISBN: 0123942950 ISBN-13(EAN): 9780123942951
Издательство: Elsevier Science
Рейтинг:
Цена: 154960.00 T
Наличие на складе: Поставка под заказ.
Описание: Gene therapy as a treatment for cancer is at a critical point in its evolution. This book offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells.

Molecular Biology of Cancer

Автор: Pecorino, Lauren
Название: Molecular Biology of Cancer
ISBN: 019957717X ISBN-13(EAN): 9780199577170
Издательство: Oxford Academ
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Цена: 38010.00 T
Наличие на складе: Невозможна поставка.
Описание: The third edition of The Molecular Biology of Cancer: Mechanisms, Targets, and Therapeutics gives a fresh approach to the study of the molecular basis of cancer, by showing how our understanding of the defective mechanisms which drive cancer is leading to the development of new targeted therapeutic agents. Written with the student learner in mind, the book features a variety of learning features to help students engage with, and master, the concepts presented. The emphasis is not on exhaustive coverage of the field, but on acquiring a solid understanding of the essentials of the subject - and an appreciation of how a theoretical understanding can be transformed into therapeutic benefit.

DNA Methylation and Cancer Therapy

Автор: Moshe Szyf
Название: DNA Methylation and Cancer Therapy
ISBN: 1441934162 ISBN-13(EAN): 9781441934161
Издательство: Springer
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Цена: 213360.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Once techniques to probe the methylation profile of whole genomes as well as specific genes became available, it became clear that DNA methylation patterns are gene and tissue specific and that patterns of gene expression correlate with patterns of methylation.

Microspheres and Regional Cancer Therapy

Автор: Willmott
Название: Microspheres and Regional Cancer Therapy
ISBN: 0849369525 ISBN-13(EAN): 9780849369520
Издательство: Taylor&Francis
Рейтинг:
Цена: 357280.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Microspheres and Regional Cancer Therapy takes an interdisciplinary approach to the subject of microspheres and regional cancer therapy

Epigenetic Cancer Therapy

Автор: Steven Gray
Название: Epigenetic Cancer Therapy
ISBN: 0128002069 ISBN-13(EAN): 9780128002063
Издательство: Elsevier Science
Рейтинг:
Цена: 116780.00 T
Наличие на складе: Поставка под заказ.
Описание:

Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.

The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).

The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.



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