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Astrocytes and Epilepsy, Hubbard, Jacqueline


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Автор: Hubbard, Jacqueline
Название:  Astrocytes and Epilepsy
ISBN: 9780128024010
Издательство: Elsevier Science
Классификация:

ISBN-10: 0128024011
Обложка/Формат: Hardback
Страницы: 250
Вес: 0.98 кг.
Дата издания: 28.07.2016
Язык: English
Размер: 281 x 199 x 27
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
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Поставляется из: Европейский союз
Описание:

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become medically refractory. Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy.

Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy.


  • Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume
  • Provides a great resource on the field of astrocyte biology and astrocyte-neuron interactions
  • Details potential therapeutic targets, including chapters on gap junctions, water and potassium channels, glutamate and adenosine metabolism, and inflammation


Childhood Epilepsy

Автор: Appleton
Название: Childhood Epilepsy
ISBN: 0521763258 ISBN-13(EAN): 9780521763257
Издательство: Cambridge Academ
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Цена: 60190.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Although many children with epilepsy will be referred to specialist units, the majority will initially present to paediatricians and paediatric neurologists. This book provides a practical, problem-oriented manual to help these clinicians with the diagnosis, evaluation and management of children presenting in infancy, middle childhood and adolescence.

Epilepsy and Memory

Автор: Adam Zeman, Narinder Kapur
Название: Epilepsy and Memory
ISBN: 0199580286 ISBN-13(EAN): 9780199580286
Издательство: Oxford Academ
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Цена: 145200.00 T
Наличие на складе: Невозможна поставка.
Описание: Epilepsy is one of the most common potentially serious disorders of the brain, and patients often suffer from memory problems. This book comprehensively reviews all aspects of the relationship between this common and potentially serious neurological disorder and memory, one of the core functions of the human mind.

Oxford Textbook of Epilepsy and Epileptic Seizures

Автор: Shorvon Simon
Название: Oxford Textbook of Epilepsy and Epileptic Seizures
ISBN: 0199659044 ISBN-13(EAN): 9780199659043
Издательство: Oxford Academ
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Цена: 200640.00 T
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Описание: Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

Language and epilepsy

Автор: Lebrun, Yvan Fabbro, Franco
Название: Language and epilepsy
ISBN: 1861563124 ISBN-13(EAN): 9781861563125
Издательство: Wiley
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Цена: 63310.00 T
Наличие на складе: Поставка под заказ.
Описание: There are numerous books dealing with epilepsy but none of them is entirely devoted to the manifold relationships between language and epilepsy.

Epilepsy SyndromesExpert Consult - Online, Print, and DVD

Автор: Werz & Pita Garcia
Название: Epilepsy SyndromesExpert Consult - Online, Print, and DVD
ISBN: 1416048332 ISBN-13(EAN): 9781416048336
Издательство: Elsevier Science
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Цена: 129690.00 T
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Описание: Guides you through the difficult diagnostic challenges associated with the epilepsy syndrome. Organized by epilepsy syndromes for easy reference, this book features the DVD that shows patient videos running concurrently with their EEG tracings. It helps in evaluating patients with seizures.

Epilepsy in Children.2002

Автор: Aicardi
Название: Epilepsy in Children.2002
ISBN: 0781726980 ISBN-13(EAN): 9780781726986
Издательство: Lippincott Williams & Wilkins
Цена: 125840.00 T
Наличие на складе: Поставка под заказ.
Описание: Every physician who treats children with epilepsy will welcome this new Third Edition of Dr. Aicardi's internationally acclaimed text. Dr. Aicardi and two distinguished colleagues,Alexis Arzimanoglou, MD and Renzo Guerrini, MD,have completely revised every chapter of this edition to reflect the past ten years' advances in diagnosis and thapy.The book describes in detail the types of seizures occurring during infancy, childhood, and adolescence and explains the key principles of diagnosis, prognosis, and medical and surgical treatment. This edition provides up to the minute information on anticonvulsant drugs and the genetics of epilepsy and includes a new chapter on epileptic encephalopathies.

Neuroimaging in Epilepsy

Автор: Harry Chugani, MD
Название: Neuroimaging in Epilepsy
ISBN: 0195342763 ISBN-13(EAN): 9780195342765
Издательство: Oxford Academ
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Цена: 176880.00 T
Наличие на складе: Невозможна поставка.
Описание: This book is the first to provide a comprehensive and balanced discussion of various neuroimaging techniques applied in the diagnosis and management of epilepsy. The editor has been meticulous in covering not only MRI and its latest developments, but also molecular and physiological imaging approaches, such as PET and SPECT in much greater depth than in previous volumes.

Wyllie`s Treatment of Epilepsy: Principles and Practice, 5e

Автор: Wyllie
Название: Wyllie`s Treatment of Epilepsy: Principles and Practice, 5e
ISBN: 1582559376 ISBN-13(EAN): 9781582559377
Издательство: Lippincott Williams & Wilkins
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Цена: 242530.00 T
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Описание: In one convenient source, Wyllie's Treatment of Epilepsy: Principles and Practice provides a broad, detailed, and cohesive overview of seizure disorders and contemporary treatment options. For this Fifth Edition, the editors have replaced or significantly

Neuropsychology of Epilepsy and Epilepsy Surgery

Название: Neuropsychology of Epilepsy and Epilepsy Surgery
ISBN: 0195372506 ISBN-13(EAN): 9780195372502
Издательство: Oxford Academ
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Цена: 59130.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This book provides essential information about the variety of seizure disorders and serves as a basic epilepsy reference guide for students and practicing clinical neuropsychologists. In addition to epilepsy neuropsychological assessment issues, the book provides an overview of the known
cognitive effects of seizures as well as the adaptive, emotional, and psychiatric consequences of epilepsy including a chapter on psychogenic nonepileptic seizures. Diagnostic tests, such as EEG and structural neuroimaging, are described and the leading treatment options are detailed with a chapter
on pharmacologic therapies which reviews the known cognitive and behaivoral side effects of specific antiepileptic drugs. Many of the more rare epilepsy disorders have been included in the appendices for quick and easy reference.

The book also details the role of neuropsychology within the epilepsy surgery process including pre-and post-surgery cognitive evaluations, cortical stimulation mapping, functional neuroimaging, and intracarotid amobarbital (Wada) procedures and reviews the major surgical treatment options used in
the intractable epilepsies. Case examples are dispersed throughout the text with neuropsychological results as heuristic aids. The book concludes with a glossary of epilepsy terms.

Epilepsy

Автор: Osorio
Название: Epilepsy
ISBN: 1439838852 ISBN-13(EAN): 9781439838853
Издательство: Taylor&Francis
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Цена: 265410.00 T
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Описание:

Epilepsy, one of the most prevalent neurological disorders, affects approximately 1% (greater than 60 million) of the world's population. In an estimated 20 million of these patients, seizures are not controlled even by multiple anti-seizure drugs, and are extremely difficult to predict. Epilepsy: The Intersection of Neurosciences, Biology, Mathematics, Engineering, and Physics seamlessly brings together the neurosciences, mathematics, computational sciences, engineering, physics, and clinical epileptology to present to readers a highly didactic, integrated, clear and practically useful knowledge base and research directions.

Laying out the foundations of signal analysis, data conditioning, linear and non-linear analysis, introduction to dynamical systems and fundamental anatomical and neurophysiological concepts, this book:

  • Introduces non-physicians to language and concepts necessary to establish a meaningful dialog with epileptologists
  • Introduces physicians to dynamical theory and signal processing without which interdisciplinary collaborations would not be productive
  • Mines knowledge from fields devoted to the investigation of aperiodic paroxysmal relaxation phenomena, such as earthquakes, which bear dynamical similarities with epilepsy, so as to lay the proper scientific foundations for epileptology and foster much needed therapeutic advances efficiently
  • Reviews spatiotemporal behavior of seizures, mechanisms of epileptogenesis and ictogenesis as well as of seizure control and ancillary technology
  • Calls attention to nocturnal frontal lobe epilepsy as a potentially fruitful paradigm for advancing seizure prediction.

Of all neurological disorders, epilepsy demands of investigators the broadest and deepest knowledge of dynamical, control, and system theories, knowledge that cannot be amassed without possessing a certain level of sophistication in relevant areas of neurosciences, physics, mathematics, and engineering. Narrowing the inescapable cultural chasm that commonly fragments multidisciplinary efforts, this book captures and enriches the burgeoning interdisciplinary synergism in the nascent field of dynamical epileptology.


Sleep And Epilepsy: The Clinical Spectrum

Автор: Sleep And Epilepsy: The Clinical Spectrum
Название: Sleep And Epilepsy: The Clinical Spectrum
ISBN: 0444504796 ISBN-13(EAN): 9780444504791
Издательство: Elsevier Science
Цена: 188650.00 T
Наличие на складе: Невозможна поставка.
Описание: As we look further into both the clinical and the basic sciences, it is found that sleep-epilepsy interactions are becoming better defined and yet more complex. It is known that epilepsy influences sleep, and that sleep influences epilepsy. In addition, the treatment of epilepsy can have favorable effects on sleep, and the sleep disorders that occur concomitantly with epilepsy have profound effects on seizure frequency and severity, primarily through the sleep deprivation process. With recent advances in epilepsy research, the availability of more modern techniques (particularly digital sleep and EEG recordings), and the acceptance of this specialty as a significant area for both clinicians and for basic research scientists, this is the appropriate time for a comprehensive textbook. The full impact of the sleep-epilepsy field, for both clinicians and basic research scientists, is given in this book. The book is divided into five sections: (1) Sleep Physiology; (2) Clinical Relationships Between Sleep and Seizures; (3) Syndromes of Sleep-Related Epilepsy; (4) Diagnostic Techniques; and Sleep Disorders and Epilepsy. This edition contains relevant information that may be incorporated into the clinical daily practice of both epilepsy and sleep disorders.

Neuropsychology of Childhood Epilepsy

Автор: Jambaque Isabelle, Lassonde Maryse, Dulac Olivier
Название: Neuropsychology of Childhood Epilepsy
ISBN: 0306465221 ISBN-13(EAN): 9780306465222
Издательство: Springer
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Цена: 213360.00 T
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Описание: While a great number of textbooks have been devoted to various medical aspects of childhood epilepsy, none have been as comprehensive and forthright as Neuropsychology of Childhood Epilepsy. Devoted to the neuropsychological description of childhood epilepsy, the editors have uncovered this neurological condition as never before. Divided into three sections, section one may be highly regarded as a necessary introduction to the neuropsychological basis of childhood epilepsy, electro-clinical patterns of various types of epilepsy and brain maturation while section two delves into the characterization of the neuropsychological profile that accompanies focal epilepsies leading to the behavioral and cognitive impairments linked to the transient events that often go unnoticed. Part three covers the medical, surgical and socio-educational management of childhood epilepsy. bsenteeism, learning difficulties, and cognitive dysfunctions may have an impact on a child's self-esteem and upon his or her quality of life. The final part of the volume therefore presents an accurate account of the vast psychological consequences of this disease. This volume is a must read for experimental and cognitive neuropsychologists, medical specialists involved in the care of children with epilepsy and professionals and caretakers dealing with the different aspects of childhood epilepsy alike.


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