Ion channels as therapeutic targets,103, Rossen Donev

Автор: Rossen Donev
Название: Ion channels as therapeutic targets, part B,104
ISBN: 0128048263 ISBN-13(EAN): 9780128048269
Издательство: Elsevier Science
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This volume is the second part ofthe thematic on "Ion Channels as Therapeutic Targets."

The popular "Advances in Protein Chemistry and Structural Biology" series, an essential resource for protein chemists, brings forth new information about protocols and analysis of proteins, with each thematically organized volume guest edited by leading experts in a broad range of protein-related topics.
Provides cutting-edge developments in protein chemistry and structural biologyDiscusses the use of ion channels as therapeutic targetsChapters are written by authorities in their fieldTargeted to a wide audience of researchers, specialists, and students"

Автор: Vadim Demidchik; Frans J.M. Maathuis
Название: Ion Channels and Plant Stress Responses
ISBN: 3642262953 ISBN-13(EAN): 9783642262951
Издательство: Springer
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Цена: 156720.00 T
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Описание: Providing a range of perspectives on the topic, this overview presents the role of ion channels in plant stress responses. New insights into plant CA2+ signaling, salinity tolerance mechanisms, cyclic nucleotide gated channels and more are covered.

Название: Receptor and Ion-channel Trafficking: Cell Biology of Ligand-gated and Voltage-sensitive Ion Channels
ISBN: 0192632248 ISBN-13(EAN): 9780192632241
Издательство: Oxford Academ
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Описание: This book reviews the recent advances in our understanding of the the molecular and cellular mechanisms regulating the targeted movement (trafficking) of receptors and ion channels in neurones - mechanisms fundamental to synaptic function.

Автор: Chung S.H., Andersen O.S., Krishnamurthy V.
Название: Biological Membrane Ion Channels / Dynamics, Structure, and Applications
ISBN: 0387333231 ISBN-13(EAN): 9780387333236
Издательство: Springer
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Описание: Deals with breakthroughs in ion-channel research that have been brought about by joint efforts of experimental biophysicists and computational physicists, who together are beginning to unravel the story of these designed biomolecules. This book is aimed at researchers in nanodevices and biosensors, undergraduate and graduate students in biology.

Автор: Kevin Wickman
Название: GIRK Potassium Channels,123
ISBN: 0128024585 ISBN-13(EAN): 9780128024584
Издательство: Elsevier Science
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Цена: 162820.00 T
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This volume in the International Review of Neurobiology series is a comprehensive overview of the state-of-the-art research into GIRK Potassium Channels. It reviews current knowledge and understanding and provides a starting point for researchers and practitioners entering the field.

Автор: Arpad Szallasi
Название: TRP Channels as Therapeutic Targets
ISBN: 0124200249 ISBN-13(EAN): 9780124200241
Издательство: Elsevier Science
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Описание: TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. . This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. . An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. . Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings.

Автор: Levitan, PhD
Название: Vascular Ion Channels in Physiology and Disease
ISBN: 3319296337 ISBN-13(EAN): 9783319296333
Издательство: Springer
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Цена: 158380.00 T
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Описание: Ion channels are the major class of membrane proteins responsible for rapid and regulated transport of ions across biological membranes and for the generation and propagation of electrical signals in the brain, heart, and skeletal and vascular tissues. Ion channels are also known to play critical roles in regulation of cell proliferation, insulin secretion and intracellular signaling in a variety of cell types. This book focuses on the roles of ion channels in vascular tissues under normal and pathological conditions. Vascular abnormalities are known to underlie a plethora of severe pathological conditions, such as atherosclerosis, systemic and pulmonary hypertension, coronary or cerebral vasospasm, and diabetes. In addition, misregulated angiogenesis is one of the major contributors to the development of tumors. Therefore, it is clearly imperative to obtain a better understanding of the molecular mechanisms that contribute to vascular disorders. This book will be the first comprehensive assembly of assays to present the studies that have been done during the last decade to elucidate the roles of ion channels in different vascular diseases.