Intramembrane-Cleaving Proteases (I-CLiPs), Hooper

Автор: Gelb, Michael H
Название: Enzymology at the Membrane Interface: Intramembrane Proteases,584
ISBN: 0128122137 ISBN-13(EAN): 9780128122136
Издательство: Elsevier Science
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Цена: 162820.00 T
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Описание:

Enzymology at the Membrane Interface: Intramembrane Proteases, Volume 584, the latest release in the Methods in Enzymology series, covers a subset of enzymes that work in the environment of the biological cell membrane. This field, called interfacial enzymology, involves a special series of experimental approaches for the isolation and study of these enzymes.

Автор: Uwe Lendeckel; Nigel M. Hooper
Название: Viral Proteases and Antiviral Protease Inhibitor Therapy
ISBN: 9400726007 ISBN-13(EAN): 9789400726000
Издательство: Springer
Цена: 204040.00 T
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Автор: Nathalie Vergnolle; Michel Chignard
Название: Proteases and Their Receptors in Inflammation
ISBN: 3034803427 ISBN-13(EAN): 9783034803427
Издательство: Springer
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Цена: 174130.00 T
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Описание:

Proteases are everywhere from prokaryotes to eukaryotes, from virus to bacteria and in all human tissues, playing a role in many biological functions. Among these functions, the inflammatory reaction is of particular interest. In inflamed tissues, proteases can have a microbial and/or host origin and are involved not only in tissue remodeling, but also in specific signaling to resident or inflammatory cells, thereby contributing to the innate immune response.

This volume presents all advances in our knowledge of the role proteases and their inhibitors play in various diseases associated with inflammatory response. Mechanisms involved in protease signaling to cells are presented, and the different types of proteases that are present at inflammatory sites and their effects on the course of inflammation are discussed. Finally, the evidence for considering proteases and their receptors as potential molecular targets for therapeutic interventions in the treatment of inflammatory diseases is discussed in the context of specific organ inflammatory pathologies (the lung, gastrointestinal tract, skin, joints, etc.).

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Автор: Nigel M Hooper; Uwe Lendeckel
Название: The ADAM Family of Proteases
ISBN: 1441937757 ISBN-13(EAN): 9781441937759
Издательство: Springer
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Цена: 174130.00 T
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Описание: The ADAM Family of Proteases provides the first comprehensive review of the roles of ADAMs and the related ADAMTS proteases in biology and disease.

Автор: Uwe Lendeckel; Nigel M. Hooper
Название: Proteases in Gastrointestinal Tissues
ISBN: 9048171342 ISBN-13(EAN): 9789048171347
Издательство: Springer
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Цена: 213360.00 T
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Описание: This book is unique for its comprehensive presentation of protease function in the stomach, colon, pancreas and liver under both physiological conditions and major diseases manifesting in these four organs.