Gerald Werner Zamponi Voltage-Gated Calcium Channels 9781441934116

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Автор: Gerald Werner Zamponi
Название: Voltage-Gated Calcium Channels
ISBN: 9781441934116
Издательство: Springer
Классификация:

Физиология

Сердечно-сосудистая медицина

Фармакология

Прикладная физика и специальные темы

Науки о жизни (медико-биологические): общие вопросы

Биохимия

ISBN-10: 1441934111
Обложка/Формат: Paperback
Страницы: 394
Вес: 0.55 кг.
Дата издания: 2005
Серия: Molecular Biology Intelligence Unit
Язык: English
Размер: 234 x 156 x 21
Читательская аудитория: Professional & vocational
Ссылка на Издательство: Link
Поставляется из: Германии
Описание: oltage-gated calcium channels are essential mediators of a range of physiological functions, including the communication between nerve Vcells, the regulation of heart beat, muscle contraction, and secretion of hormones such as insulin. Consequently, these channels are critical phar- macological targets in the treatment of a variety of disorders, such as epi- lepsy, hypertension, and pain. Voltage-gated calcium channels have there- fore been subject to intense study by numerous investigators over the past few decades, and an immense body of work has accumulated. In this book, we provide the first comprehensive overview of our current state of knowl- edge concerning this exciting field of research. Leading off with a general review of calcium signaling and techniques to measure calcium channel ac- tivity, the book delves into a provocative overview of the history of the cal- cium channel field, contributed by one of the key pioneers in the field. Dr. Richard Tsien. This is followed by an in depth review of the biochemical and molecular biological characterization of calcium channel genes by Drs. Catterall and Snutch whose research has resulted in major advances in the calcium channel field. A number of chapters are dedicated towards various aspects of calcium channel structure and function, including channel gat- ing, permeation, modulation and interactions with members of the exo- totic machinery--contributed by both established leaders and rising stars in the field.

Voltage-Gated Calcium Channels, Gerald Werner Zamponi