The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.
This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.
The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.
Автор: Pomper Название: Molecular Imaging in Oncology ISBN: 0849374170 ISBN-13(EAN): 9780849374173 Издательство: Taylor&Francis Рейтинг: Цена: 357280.00 T Наличие на складе: Нет в наличии. Описание: With molecular imaging becoming one the fastest growing topics in medical schools, Informa Healthcare presents Molecular Imaging in Oncology, the first comprehensive reference on molecular imaging in oncology.Filled with over 500 images, of which more than 50 are in color, illustrating diagnostic and therapeutic capabilities of molecular imaging in cancer, this text outlines all procedures for radiologists, radiology physicists, and radiation oncologists in a concise, single-source guide.
Автор: Gustav K. von Schulthess Название: Clinical Molecular Anatomic Imaging: PET/CT, PET/MR and SPECT CT ISBN: 1451192665 ISBN-13(EAN): 9781451192667 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 320320.00 T Наличие на складе: Невозможна поставка. Описание: Discusses techniques and combination for each disease. This book provides guidance on which modality to use. It is a disease oriented reference meant for interpreting integrated imaging studies.
Автор: von Schulthess Название: Molecular anatomic imaging ISBN: 0781776740 ISBN-13(EAN): 9780781776745 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 231090.00 T Наличие на складе: Невозможна поставка. Описание: "This fully updated Second Edition is perfect for clinicians, as it focuses sharply on clinical PET-CT and SPECT-CT examinations, omitting lengthy physics discussions. The book is now strictly disease oriented and integrates PET-CT and SPECT-CT applications completely. When both techniques are relevant for a disease, they are discussed together; when only one is relevant, it is discussed alone. More than 1,200 illustrations document the use of integrated imaging and provide very useful reference material for interpreting integrated imaging studies.
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