Автор: Albitar Maher Название: Monoclonal antibodies / methods and protocols ISBN: 1588295672 ISBN-13(EAN): 9781588295675 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Поставка под заказ. Описание: Monoclonal Antibodies: Methods and Protocols examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting with opening chapters focusing on the gold standard method for generating mouse monoclonal antibodies through hybridoma technology, future methods for engineering recombinant and humanized antibodies, methods for engineering soluble Fc fusion protein, and the use of antibodies and flow cytometry in the quantification of cell signaling proteins. Specific chapters describe how antibodies are used for the diagnosis and classification of hematologic diseases. Subsequent chapters examine the advantages and most recent advances of using bead-based immunoassays, including the ability of bead-based technology to multiplex and analyze several analytes simultaneously, and the use of beads in detecting fusion proteins resulting from chromosomal translocations. Concluding chapters provide additional examples of methodologies that employ monoclonal antibodies.Monoclonal Antibodies: Methods and Protocols provides descriptions of methods that cover a wide spectrum of applications in the field of monoclonal antibodies. This field will continue to expand and provide new and innovative techniques, not only in the laboratory, but also as a basis that complements targeted therapy.
Автор: R. Gieseler; Johann H. Peters; G. K?hler; P. Debba Название: Monoclonal Antibodies ISBN: 3642745342 ISBN-13(EAN): 9783642745348 Издательство: Springer Рейтинг: Цена: 121890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: With contributions by numerous authors
Автор: Roger H. Kennett Название: Monoclonal Antibodies ISBN: 1461575079 ISBN-13(EAN): 9781461575078 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: On August 7, 1975, Kohler and Milstein published in Nature (256:495) a report describing Continuous cultures of fused cells secreting antibody of predefined specificity. Their report has become a classic and has already had a profound effect on basic and applied research in biology and medicine. By the time the first Workshop on Lymphocyte Hybridomas (Current Topics in Microbiology and Im- munology 81, 1978) was held on April 3-5, 1978, in Bethesda, Maryland, investi- gators from many laboratories had made hybrids between plasmacytomas and spleen cells from immunized animals and had obtained monoclonal antibodies reacting with a broad variety of antigenic determinants. At the time Kohler and Milstein introduced this new technology, the editors of this volume were involved in the production of antisera against differentiation antigens (K. B. B. ), histocompatibility antigens (T. ]. McK. ), and human tumor- associated antigens (R. H. K. ). Because of the potential usefulness of monoclonal antibodies in these areas, we each began production of hybridomas and analysis of the resulting monoclonal reagents. One of the most interesting aspects of participation in the early stages of the development and application of hybrid- oma technology has been observing how the implications of the initial observa- tions gradually spread first among the practitioners of immunology and immu- nogenetics, and then to other areas of the biological sciences, such as developmental biology, biochemistry, human genetics, and cell and tumor biology.
Автор: Suresh C. Srivastava Название: Radiolabeled Monoclonal Antibodies for Imaging and Therapy ISBN: 1468455400 ISBN-13(EAN): 9781468455403 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The advent of hybridoma technology leading to the successful produc- tion of monoclonal antibodies against a variety of tumor-associated antigens has, during the last decade, provided a very powerful tool for research and clinical investigations.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1627039910 ISBN-13(EAN): 9781627039918 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies.
Автор: Ritter Название: Monoclonal Antibodies ISBN: 0521425034 ISBN-13(EAN): 9780521425032 Издательство: Cambridge Academ Рейтинг: Цена: 98200.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Monoclonal antibodies have a very important and wide-ranging role in many areas of biomedical research and this volume is amongst the very first to combine technical and clinical aspects of the subject.
Автор: Shepherd Название: Monoclonal Antibodies ISBN: 0199637229 ISBN-13(EAN): 9780199637225 Издательство: Oxford Academ Рейтинг: Цена: 89760.00 T Наличие на складе: Поставка под заказ. Описание: This text covers the preparation, testing, derivation and application of monoclonal antibodies. Modern immunological techniques incorporating tried and tested methodologies are described, as well as the standard somatic hybridization and recombinant techniques, including the use of phage libraries.
Автор: Edgar Engleman Название: Human Hybridomas and Monoclonal Antibodies ISBN: 1468449516 ISBN-13(EAN): 9781468449518 Издательство: Springer Рейтинг: Цена: 113190.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Soon after Kohler and Milstein described the use of somatic cell hybridization for the production of murine monoclonal antibodies of desired specificity, this relatively simple technique became widely applied.
Автор: Michael Steinitz Название: Human Monoclonal Antibodies ISBN: 1493960199 ISBN-13(EAN): 9781493960194 Издательство: Springer Рейтинг: Цена: 111790.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book details readily reproducible protocols of cellular and molecular methods for the production, purification and application of human monoclonal antibodies. It also includes articles on related topics of human monoclonal and polyclonal antibodies.
Автор: Vincent Ossipow; Nicolas Fischer Название: Monoclonal Antibodies ISBN: 1493963228 ISBN-13(EAN): 9781493963225 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Monoclonal Antibodies: Methods and Protocols, Second Edition expands upon the previous edition with current, detailed modern approaches to isolate and characterize monoclonal antibodies against carefully selected epitopes. This edition includes new chapters covering the key steps to generate high quality monoclonals via different methods, from antigen generation to epitope mapping and quality control of the purified IgG. Chapters are divided into four parts corresponding to four distinct objectives. Part I covers monoclonal antibody generation, Part II deals with monoclonal antibody expression and purification, Part III presents methods for monoclonal antibody characterization and modification, and Part IV describes selected applications of monoclonal antibodies. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Monoclonal Antibodies: Methods and Protocols, Second Edition provides crucial initial steps of monoclonal antibody generation and characterization with state-of-the art protocols.
Автор: Maher Albitar Название: Monoclonal Antibodies ISBN: 1617376469 ISBN-13(EAN): 9781617376467 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines a collection of state-of-the-art methods that employ monoclonal antibodies in a clinical setting. The chapters offer in-depth description for generating mouse and recombinant humanized antibodies, and a comprehensive review of how antibodies are being used in bead-based methods for measuring proteins.
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