Автор: Yang Sherry X., Dancey Janet E. Название: Handbook of Therapeutic Biomarkers in Cancer ISBN: 981487700X ISBN-13(EAN): 9789814877008 Издательство: Taylor&Francis Цена: 235810 T Описание: This book provides a comprehensive overview of the fast-evolving subject of clinical application of cancer therapeutic biomarkers. The second edition captures significant progress of cancer immunotherapy and emphasizes the genetic basis for selective cancer treatment.
Автор: Jain K.K. Название: The Handbook of biomarkers ISBN: 160761684X ISBN-13(EAN): 9781607616849 Издательство: Springer Рейтинг: Цена: 174150.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This handbook describes many different types of biomarkers and their discovery. It also presents the background information needed for the evaluation of biomarkers as well as the essential procedures for their validation and use in clinical trials.
Автор: Armstrong Donald Название: Oxidative Stress Biomarkers and Antioxidant Protocols ISBN: 0896038505 ISBN-13(EAN): 9780896038509 Издательство: Springer Рейтинг: Цена: 144410.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Donald Armstrong updates and expands his highly praised Free Radical and Antioxidant Protocols (Humana, 1998) with a collection of new and valuable methods for evaluating the pertubations in cell function resulting from increased oxidative stress. Presented in a user-friendly, step-by-step format, these readily reproducible techniques cover both free radical-derived and antioxidant biomarkers. The methodologies demonstrated include ELISA, HPLC, infrared spectroscopy, gas chromatography-mass spectroscopy, immunoblotting, electroelution fractionation, isoelectric focusing, voltametry, and electron paramagnetic resonance imaging. Special emphasis is given to the separation of complex mixtures of plant antioxidants, soft drug design to protect from toxic oxidative metabolites, in vitro oxidation conditions, and correcting for random measurement error to improve statistical interpretation. A soon-to-be-published companion volume, Oxidants and Antioxidants: Ultrastructural and Molecular Biology Protocols (0-89603-851-3), contains state-of-the-art molecular and ultrastructural methods that expand the total number of protocols to 109 assays.
Название: Cancer Biomarkers ISBN: 1578087619 ISBN-13(EAN): 9781578087617 Издательство: Taylor&Francis Рейтинг: Цена: 153120.00 T Наличие на складе: Невозможна поставка. Описание: This unique synthesis of chapters from top experts in their fields targets the essential area of cancer biomarkers and the need for better and more rigorous design and clinical trials.
Автор: Gabriel D. Dakubo Название: Cancer Biomarkers in Body Fluids ISBN: 3319483595 ISBN-13(EAN): 9783319483597 Издательство: Springer Рейтинг: Цена: 214280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book examines in depth the evidence, clinical applications and potential cancer signatures in the circulation and discusses alterations in circulating cell-free nucleic acids, and circulating tumor DNA, as well as the epigenome, genome, transcriptome (coding and noncoding), proteome (both traditional serum proteins and proteomic profiles) and metabolome. Further, it highlights the clinical applications of circulating tumor cells for each cancer type and addresses the emerging importance of extracellular vesicular contents, including miRNA, oncogenes and drug resistant factors. As such, it offers a valuable reference guide for cancer researchers, oncologists, clinicians, surgeons, medical students, oncology nurses, diagnostic laboratories, and the pharmaceutical industry.
Название: Biomarkers of disease ISBN: 0521088607 ISBN-13(EAN): 9780521088602 Издательство: Cambridge Academ Рейтинг: Цена: 67590.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options.
Автор: Dakubo Название: Cancer Biomarkers in Body Fluids ISBN: 3319015796 ISBN-13(EAN): 9783319015798 Издательство: Springer Рейтинг: Цена: 167700.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The molecular and genetic signatures of cancer are represented in the peripheral circulation and other body fluids, giving rise to the “liquid biopsy” concept. This new paradigm of molecular profiling of cancer cells offers several advantages over traditional tissue biopsy. It is convenient, noninvasive, conforms to current clinical practice, enables real time disease monitoring and the study of tumor evolution, can easily be sampled multiple times, and this sample is more representative of the heterogeneous cancer cells than biopsy sampling. Indeed, all aspects of cancer molecular genetic information, stemming from DNA (both nuclear and mitochondria), RNA (coding and noncoding), peptides and proteins, metabolites and lipids are present in body fluids as free, cell surface bound or enclosed in membrane vesicles, and are being harnessed for disease management. Additionally, circulating tumor, and tumor stem cells provide prognostic information, and also enable the study of the intricate molecular processes associated with metastasis and drug resistance. This treatise deals with the general principles of the molecular pathology of cancer, and its associated imprints in circulation. The transitional process from discovery, prototype development, translational research, to product development can be complex and costly. The critical path to biomarker development and qualification for successful use in drug development is detailed herein as well.This book is of interest to Cancer Researchers, Oncologists, Clinicians, Surgeons, Medical Students, Nurses, Diagnostic Laboratories, and Pharmaceutical Industries.??
Автор: Edited by Andrew K. Trull Название: Biomarkers of Disease ISBN: 0521811023 ISBN-13(EAN): 9780521811026 Издательство: Cambridge Academ Рейтинг: Цена: 260830.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This publication takes a critical, evidence-based look at the efficacy of diagnostic tests which are increasingly being used to evaluate organ damage and dysfunction. Some of these assist in diagnosis, others provide a means of monitoring the state of progression of disease and the effectiveness of therapeutic options.
Автор: Harndan Название: Cancer Biomarkers. 2007 ISBN: 0471745162 ISBN-13(EAN): 9780471745167 Издательство: Wiley Рейтинг: Цена: 142510.00 T Наличие на складе: Поставка под заказ. Описание: Tools, techniques, and progress in cancer biomarkers discovery The completion of a number of gene sequencing projects, recent advances in genomic and proteomic technologies, and the availability of powerful bioinformatics tools have led to promising new avenues and approaches in the search for cancer biomarkers.
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