Cancer Chemotherapy in Clinical Practice, Priestman, Terrence
Автор: Priestman Название: Cancer Chemotherapy in Clinical Practice ISBN: 1846289890 ISBN-13(EAN): 9781846289897 Издательство: Springer Рейтинг: Цена: 55640 T Наличие на складе: Есть Описание: Summarizes a range of systemic cancer therapies, explaining their mode of action and potential side-effects, as well as their clinical applications. This text explains the principles underlying cancer chemotherapy. It also explains the place of drug treatment, and the outcomes that can be expected from chemotherapy, in major cancers.
Автор: Markman Maurie Название: Regional Chemotherapy / Clinical Research and Practice ISBN: 0896037290 ISBN-13(EAN): 9780896037298 Издательство: Springer Рейтинг: Цена: 221830 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Maurie Markman and a panel of distinguished clinicians and leading clinical investigators comprehensively review the current status of regional antineoplastic drug delivery in the management of malignant disease. These authorities present a critical analysis of both the rationale and limitations of regional therapy and discuss potential clinical trials designed to explain the effectiveness of this method of therapy in special settings. Their presentations describe many exciting and innovative strategies for using regional drug delivery in anticancer therapy, including coverage of such areas of special interest as colorectal, skin, lung, pancreatic, ovarian, and gastrointestinal cancers. Comprehensive and authoritative, Regional Chemotherapy: Clinical Research and Practice offers surgical and medical oncologists and clinical cancer investigators a gold-standard review of the current role and future development of this increasingly powerful weapon in the battle against cancer.
Автор: Aigner, Karl Reinhard; Stephens, Frederick O. (Eds Название: Induction chemotherapy: integrated treatment programs for locally advanced cancers ISBN: 3642181724 ISBN-13(EAN): 9783642181726 Издательство: Springer Рейтинг: Цена: 106730 T Наличие на складе: Нет в наличии. Описание: Induction chemotherapy, as part of an integrated plan of management for locally advanced cancers, is being practiced throughout the world, but frequently teams are unaware of the work being undertaken in other institutions. This book aims to present the full range of management techniques used in induction chemotherapy within one accessible volume. It provides up-to-date information on pioneering and cutting edge practices and documents the advantages of integrated treatment schedules. Patient selection is discussed, and each of the cancer types for which induction therapy has proved important is considered in detail. All who are responsible for the treatment of patients with locally advanced cancers will find this book to be an invaluable source of information. It will be particularly interesting for specialist oncologists aiming to set up fully comprehensive cancer centers and for health administrators wishing to learn about the benefits of establishing such centers in strategic locations.
Автор: La Thangue Nicholas B., Bandara Lasantha R. Название: Targets for Cancer Chemotherapy ISBN: 0896039382 ISBN-13(EAN): 9780896039384 Издательство: Springer Рейтинг: Цена: 212540 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In Targets for Cancer Chemotherapy: Transcription Factors and Other Nuclear Proteins, a panel of leading basic researchers, pharmaceutical scientists, and clinical oncologists explain in detail the therapeutically-relevant protein targets that contribute to cancer pathology and spell out their implications for cancer drug discovery and clinical application. The authors identify and illuminate selected transcription factor oncoproteins and tumor suppressors, together with nuclear proteins that are central to the phenotype of the tumor cell involved in chromatin control. The emphasis is on new targets and approaches to cancer treatment derived from the cancer cell cycle, gene control targets, and angiogenesis.
Автор: Chabner Название: Cancer Chemotherapy and Biotherapy ISBN: 0781756286 ISBN-13(EAN): 9780781756280 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 158810 T Наличие на складе: Невозможна поставка. Описание: "Updated to include the newest drugs and those currently in development, this Fourth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents--their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition provides expanded coverage of monoclonal antibodies, molecularly targeted drugs, vaccines, cell based therapies, growth factors, and pharmacogenetics.
Автор: Saltz Leonard B. Название: Colorectal Cancer / Evidence-based Chemotherapy Strategies ISBN: 1588297519 ISBN-13(EAN): 9781588297518 Издательство: Springer Рейтинг: Цена: 185630 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Focuses on the medical care of patients with colorectal cancer. Thorough reviews of the treatment strategies and scenarios, this work provides evidence-based discussions of the rationale supporting the use of many different options that might be used to treat patients with colorectal cancer.
Автор: Hickman John A., Dive Caroline Название: Apoptosis and Cancer Chemotherapy ISBN: 0896037436 ISBN-13(EAN): 9780896037434 Издательство: Springer Рейтинг: Цена: 185630 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This collection of thoughtful and provocative articles focused on the key issues in apoptosis, ranges from the role of apoptosis in defining the response of authentic tumor populations to chemotherapeutic agents to the mechanisms coupling DNA damage to the activation pathway of apoptosis. It reviews the profusion of new signaling, modulating, and effector molecules now implicated in apoptosis and whether other routes to "programmed" cell death may exist. Also addressed are the nature of the molecules that will either constitute targets for future drugs or influence the efficacy of current therapies, as well as mechanistic questions on the control of apoptosis. By focusing on essential questions and critically summarizing the overwhelming tide of recent research results, Apoptosis and Cancer Chemotherapy illuminates not only the potential targets for tumor therapy, but beyond that, potential control points for cancer and such diverse diseases as viral infection, neurodegenerative disorders, and stroke. This collection of cutting-edge reviews by established leaders in the field critically summarizes the recent discoveries concerning apoptosis, cell suicide. The book looks forward to the time when such cell death can be controlled to treat cancer and a host of other diseases as diverse as viral infection, neurodegenerative disorders, and stroke.
Автор: Andersson Borje, Murray David Название: Clinically Relevant Resistance in Cancer Chemotherapy ISBN: 1402072007 ISBN-13(EAN): 9781402072000 Издательство: Springer Рейтинг: Цена: 203260 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The introduction of new anticancer drugs and drug combinations, as well as the use of high-dose chemotherapy with growth factor and hemopoietic stem cell support, has greatly increased clinical remission rates. Unfortunately palliation, rather than cure, remains the most realistic goal of chemotherapy for many patients. The failure to cure metastatic cancer is commonly attributed to drug "resistance". Resistance can be broadly viewed as the survival of malignant cells because of a failure to deliver an effective drug dose to the (cellular) target, resulting from any one of or combination of individual factors. For example, inter-individual genetic differences in drug metabolism, as well as differences in tumor kinetics and vascularization, may be important for treatment outcome. In addition, numerous molecular mechanisms of resistance have been elucidated at the level of the individual tumor cell. The present volume reviews clinically relevant aspects of the pharmacokinetics of commonly used anticancer agents as well as mechanisms of cellular/experimental resistance to such agents. This extends to technological advances that enable high-throughput studies of genetic polymorphisms, which has opened up new avenues to the study of drug resistance and to the individualization of chemotherapy in order to decrease clinical toxicity and optimize treatment results. "This text provides a comprehensive review of the mechanisms of resistance to cancer chemotherapuetic agents. Leading experts discuss molecular and biochemical pathways that influence cytotoxicity. Knowledge of these potential obstacles to therapy will allow for the development of more effective strategies to treat malignant diseases." Steven T. Rosen, M.D., Series Editor
Автор: Andrea Bonetti; Roberto Leone; Franco Muggia; Step Название: Platinum and Other Heavy Metal Compounds in Cancer Chemotherapy ISBN: 1603274588 ISBN-13(EAN): 9781603274586 Издательство: Springer Рейтинг: Цена: 231110 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The platinum-containing chemotherapeutic agents remain key components of many of the most effective regimens for the treatment of cancer. This book provides summaries of various developments in field of platinum drug therapy drawn from presentations made at the 10th International Symposium on Platinum Coordination Compounds in Cancer Chemotherapy.
Автор: Skeel Название: Handbook of Cancer Chemotherapy 8ed ISBN: 160831782X ISBN-13(EAN): 9781608317820 Издательство: Lippincott Williams & Wilkins Рейтинг: Цена: 66930 T Наличие на складе: Невозможна поставка. Описание: Skeel's Handbook of Cancer Chemotherapy combines in one place the most current rationale and specific details necessary to safely administer chemotherapy for most adult cancers. The handbook is a practical, diseased-focused pocket reference that emphasizes the best current medical practice as it relates to the delivery of chemotherapeutic drugs. By focusing on specific plans for treatment, the book is an invaluable resource for the daily care of cancer patients.
Автор: Greenwood Название: Antimicrobial Chemotherapy 5/e P. 2007 ISBN: 0198570163 ISBN-13(EAN): 9780198570165 Издательство: Oxford Academ Рейтинг: Цена: 45140 T Наличие на складе: Поставка под заказ. Описание: Aims to encourage good prescribing habits in doctors throughout the world, by describing the basic properties of antibiotics and other antimicrobial agents, and discussing the principles underlying the rational use of antimicrobial agents in the management of infection.
Автор: Finch, Roger; Davey, Peter; Wilcox, Mark H.; Irvin Название: Antimicrobial Chemotherapy ISBN: 0199697655 ISBN-13(EAN): 9780199697656 Издательство: Oxford Academ Цена: 45180 T Наличие на складе: Поставка под заказ. Описание: Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the ne
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