Targeted therapies in breast cancer, Burstein, Harold
Автор: Colotta Francesco, Mantovani Alberto Название: Targeted Therapies in Cancer / Myth or Reality? ISBN: 0387738975 ISBN-13(EAN): 9780387738970 Издательство: Springer Рейтинг: Цена: 93010 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: In September 2005 an International Meeting on "Targeted Therapies in Cancer: Myth or Reality" was held in Milan. This book collects the contributions given by scientists and clinicians, from Academia and Industry, who participated to this Meeting. It provides an overview of diverse approaches ranging from drug discovery to cellular therapy.
Автор: Francesco Colotta; Alberto Mantovani Название: Targeted Therapies in Cancer: ISBN: 1441925376 ISBN-13(EAN): 9781441925374 Издательство: Springer Рейтинг: Цена: 93010 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This crucial text offers readers an overview of diverse approaches to targeted cancer therapies, ranging from drug discovery to cellular therapy. Overall, the book addresses the key question of whether ultimately targeted therapy in cancer will be a myth or a reality.
Автор: Giuseppe Giaccone Название: Targeted Therapies in Oncology ISBN: 1842145452 ISBN-13(EAN): 9781842145456 Издательство: Taylor&Francis Рейтинг: Цена: 92820 T Наличие на складе: Поставка под заказ. Описание:
Since the last edition of this book, major advances have been made in our understanding of key pathways that control tumor progression. This has led to the development of new anticancer agents that have the ability to block the activity of proteins involved in neoplastic cell development and proliferation. Targeted Therapies in Oncology, Second Edition provides a concise timely panorama of existing targeted therapies and progress into future anticancer treatments.
These therapies notably include:
Targeted agents of immune checkpoints
Stem cell inhibitors
Tumor profiling for drug development
The book emphasizes the biology behind this new class of drugs as well as the clinical achievements obtained. The contributors to this volume stand at the cutting edge of cancer research and treatment around the world.
Автор: Kurzrock Название: Targeted Cancer Therapy ISBN: 1603274235 ISBN-13(EAN): 9781603274234 Издательство: Springer Рейтинг: Цена: 141420 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Covers the field of uncomplicated incontinence ranging from various concepts, to surgical management, to medical management, with a focus on the diagnostic tests, the surgery including laparoscopy and medical therapies. This book also covers special topics such as prolapse, male incontinence, economic aspects, and costs and education.
Автор: Kurzrock Название: Targeted cancer therapy ISBN: 1607615983 ISBN-13(EAN): 9781607615989 Издательство: Springer Рейтинг: Цена: 74640 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Emerging technologies in target identification, drug discovery, molecular markers, and imaging are rapidly changing the face of cancer. This state-of-the-art book provides a foundation of knowledge in targeted cancer therapeutics.
Автор: Dietel Manfred Название: Targeted Therapies in Cancer ISBN: 354046090X ISBN-13(EAN): 9783540460909 Издательство: Springer Рейтинг: Цена: 124400 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: From its introduction, oncological chemotherapy has been encumbered by its poor selectivity because most antiproliferative drugs are toxic not only to tumor cells but also to important populations of the bodyвЂ™s non-neoplastic cells. The resultant problems with unwanted side effects are compounded by difficulties in predicting the desired effectivity of chemotherapy in individual patients.This unsatisfactory situation has driven intensive research and development towards more specific and less toxic anticancer drugs over the last few decades. Several results of these efforts have reached the clinic and an even greater number are now in preclinical testing.Common to all these targeted therapies is their interaction with defined molecules present on cancer cells, which adds various degrees of increased selectivity to their toxic effects. As a consequence, detecting the target molecule on tumors before therapy holds great diagnostic potential for predicting the efficacy of the drug and personalizing therapy. This book aims to present translational scientists and clinicians with an integrated critical view on the theories, mechanisms, problems and pitfalls of the targeted therapy approach.
Автор: Manfred Dietel Название: Targeted Therapies in Cancer ISBN: 3642432433 ISBN-13(EAN): 9783642432439 Издательство: Springer Рейтинг: Цена: 124400 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: From its introduction, oncological chemotherapy has been encumbered by poor selectivity because antiproliferative drugs are often toxic not only to tumor cells but also to important populations of the body`s non-neoplastic cells.
Автор: Dietmar Siemann Название: Vascular-Targeted Therapies in Oncology ISBN: 0470012943 ISBN-13(EAN): 9780470012949 Издательство: Wiley Рейтинг: Цена: 102950 T Наличие на складе: Поставка под заказ. Описание: Vascular Targeting Therapies provides an interesting insight to the current status and future potential of vascular disrupting approaches in cancer management. Emphasis is placed on target development, preclinical assessment, and the use of such targeted approaches in combination with conventional treatment regimens and the current clinical status of these therapies.
Автор: Gioeli Название: Targeted Therapies ISBN: 1607614774 ISBN-13(EAN): 9781607614777 Издательство: Springer Рейтинг: Цена: 124400 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This volume explores the mechanisms of resistance to targeted therapeutics. The focus is on the cancer cell signaling network, although other mechanisms of resistance including target mutation, and new areas of study such as cancer stem cells are included.Targeted Therapies: Mechanisms of Resistance highlights examples of changes in the signaling network in response to inhibition of a signaling event and underscores the importance in having a mechanistic understanding of the signaling network in cancer for developing effective targeted cancer therapies. Moreover, cutting edge tools to analyze the cell signaling network will be discussed. This includes the leading edge of techniques as well as computational biology and systems theory. This volume provides the reader with both an overview as well as a detailed perspective on the mechanisms of resistance to targeted therapeutics and will be of great value to the oncologist, the physician-scientist treating patients and the translational scientist working on any aspect of targeted therapeutics.
Автор: Daniel Gioeli Название: Targeted Therapies ISBN: 1617797448 ISBN-13(EAN): 9781617797446 Издательство: Springer Рейтинг: Цена: 124400 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Targeted Therapies highlights changes in the signaling network in response to inhibition of a signaling event. The text illustrates how a mechanistic understanding of the signaling network in cancer is important to developing targeted cancer therapies.
Автор: Joseph Lustgarten; Yan Cui; Shulin Li (Eds.) Название: Targeted Cancer Immune Therapy ISBN: 1441901698 ISBN-13(EAN): 9781441901699 Издательство: Springer Рейтинг: Цена: 161110 T Наличие на складе: Поставка под заказ. Описание: The principal of cancer immune therapy remains to be the stimulation of the immune system to control and destroy tumors, but the scope is expanded in steady
and fast pace, the approach is modernized every few years, new molecules are revealed annually, and the understanding of the mechanisms is getting deeper and deeper. "Targeted
Cancer Immune Therapy" covers cytokine immune therapy, cell-based immune therapy, and targeted immune therapy. In each of these three sections, only the novel aspects of immune
therapy were selectively described instead of attempting to cover any historical achievement.
In the first section, Cytokine Immune Therapy, the IL12 family, IL18, IL21, IL24,
IL28, and IL29 were heavily discussed in regard to the anti-tumor function and application in treating tumors. In the second section, Cell-based Immune Therapy, the focus was given to
engineering potent immune regulatory or effector
cells such as dendritic cells, T cells, and stem cells. The cell engineering design is primarily based on the increased understanding of the interaction of tumor antigen presenting cells,
antigen specific effector cells, and the tumor microenvironment.
In the third section, Targeted Immune Therapy, the focus was given on rearticulating the antibody therapy for
boosting immune response, which includes immunocytokines, 'T-body', and tumor targeted CpG ODN. Immunocytokines represent a new class of biopharmaceuticals composed of two
well known immune components - antibodies and cytokines - with the unique ability to target cytokines to the tumor microenvironment and thereby activate antitumor responses. Some
or all of these innovative approaches may ultimately become the future effective immune therapy for treating malignancy.
Автор: Raymond M. Reilly Название: Monoclonal Antibody and Peptide-Targeted Radiotherapy of Cancer ISBN: 0470243724 ISBN-13(EAN): 9780470243725 Издательство: Wiley Рейтинг: Цена: 99000 T Наличие на складе: Поставка под заказ. Описание: The essential, up-to-date guide to fighting cancer with targeted radiotherapy Continuing to gain momentum as a novel treatment strategy, targeted radiotherapy relies on and exploits the characteristics of malignant cells to attack tumors with radiati
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