Автор: Escors Название: Lentiviral Vectors and Gene Therapy ISBN: 3034804016 ISBN-13(EAN): 9783034804011 Издательство: Springer Рейтинг: Цена: 60940.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Gene therapy was conceived during the early and mid part of the 20th century. At first, it was considered a revolutionary biomedical procedure, which could potentially cure any disease for which the molecular bases were understood. Since then, gene therapy has gone through many stages and has evolved from a nearly unrealistic perspective to a real life application. Clinical efficacy in humans was demonstrated at the beginning of this century after its successful application in small-scale clinical trials to cure severe immunodeficiency in children. However, their successes were overshadowed some time later by the occurrence of vector-related leukaemia in a number of treated children. It is in this context that lentiviral vectors have appeared, with improved efficiency and, possibly, increased biosafety. Very recently, the first clinical trials with lentivectors have been carried out with some success. This Brief firstly defines gene therapy, and places lentivectors within this fascinating therapeutic strategy. Then follows a comprehensive description of the development of retroviral and lentiviral vectors and how to specifically target distinct cell types and tissues. The authors also discuss the application of lentivector gene therapy for the treatment of cancer and autoimmune diseases, ending with the application of lentivectors in human gene therapy clinical trials.
Название: Merck manual of diagnosis and therapy ISBN: 0911910190 ISBN-13(EAN): 9780911910193 Издательство: Wiley Рейтинг: Цена: 68110.00 T Наличие на складе: Поставка под заказ. Описание: Packed with useful information on diagnosing and treating medical disorders to help deliver the best patient care, this title features expanded clinical focus on each disorder, as well as more specific guidance on patient examinations.
Автор: Charles M. Washington Название: Principles and Practice of Radiation Therapy ISBN: 0323287522 ISBN-13(EAN): 9780323287524 Издательство: Elsevier Science Рейтинг: Цена: 208290.00 T Наличие на складе: Невозможна поставка. Описание:
The only radiation therapy text written by radiation therapists, Principles and Practice of Radiation Therapy, 4th Edition helps you understand cancer management and improve clinical techniques for delivering doses of radiation. A problem-based approach makes it easy to apply principles to treatment planning and delivery. New to this edition are updates on current equipment, procedures, and treatment planning. Written by radiation therapy experts Charles Washington and Dennis Leaver, this comprehensive text will be useful throughout your radiation therapy courses and beyond.
Comprehensive coverage of radiation therapy
includes a clear introduction and overview plus complete information on physics, simulation, and treatment planning.
Spotlights and shaded boxes identify the most important concepts.
End-of-chapter questions provide a useful review.
Chapter objectives, key terms, outlines, and summaries make it easier to prioritize, understand, and retain key information.
Key terms are bolded and defined at first mention in the text, and included in the glossary for easy reference.
UPDATED chemotherapy section, expansion of What Causes Cancer, and inclusions of additional cancer biology terms and principles
provide the essential information needed for clinical success.
UPDATED coverage ofpost-image manipulation techniques includes new material on Cone beam utilization, MR imaging, image guided therapy, and kV imaging.
NEW section on radiation safety and misadministration of treatment beams addresses the most up-to-date practice requirements.
Content updates also include new ASRT Practice Standards and AHA Patient Care Partnership Standards, keeping you current with practice requirements.
UPDATED full-color insert is expanded to 32 pages, and displays images from newer modalities.
Автор: Edmund C. Lattime Название: Gene Therapy of Cancer, ISBN: 0123942950 ISBN-13(EAN): 9780123942951 Издательство: Elsevier Science Рейтинг: Цена: 154960.00 T Наличие на складе: Поставка под заказ. Описание: Gene therapy as a treatment for cancer is at a critical point in its evolution. This book offers a comprehensive assessment of the field including the areas of suicide gene therapy, oncogene and suppressor gene targeting, immunotherapy, drug resistance gene therapy, and the genetic modification of stem cells.
Автор: Wolfgang Walther Название: Current Strategies in Cancer Gene Therapy ISBN: 3319429329 ISBN-13(EAN): 9783319429328 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book describes important developments and emerging trends in experimental and clinical cancer gene therapy. It reflects the tremendous advances made over recent years with respect to immunogenes, suicide genes and gene correction therapies, as well as in gene suppression and miRNA therapies.
Автор: Steven Gray Название: Epigenetic Cancer Therapy ISBN: 0128002069 ISBN-13(EAN): 9780128002063 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Поставка под заказ. Описание:
Epigenetic Cancer Therapy unites issues central to a translational audience actively seeking to understand the topic. It is ideal for cancer specialists, including oncologists and clinicians, but also provides valuable information for researchers, academics, students, governments, and decision-makers in the healthcare sector.
The text covers the basic background of the epigenome, aberrant epigenetics, and its potential as a target for cancer therapy, and includes individual chapters on the state of epigenome knowledge in specific cancers (including lung, breast, prostate, liver).
The book encompasses both large-scale intergovernmental initiatives as well as recent findings across cancer stem cells, rational drug design, clinical trials, and chemopreventative strategies. As a whole, the work articulates and raises the profile of epigenetics as a therapeutic option in the future management of cancer.
Автор: Willmott Название: Microspheres and Regional Cancer Therapy ISBN: 0849369525 ISBN-13(EAN): 9780849369520 Издательство: Taylor&Francis Рейтинг: Цена: 357280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Microspheres and Regional Cancer Therapy takes an interdisciplinary approach to the subject of microspheres and regional cancer therapy
Автор: Brown, Dennis M. Название: Drug Delivery Systems In Cancer Therapy ISBN: 0896038882 ISBN-13(EAN): 9780896038882 Издательство: Springer Рейтинг: Цена: 200260.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Leading experts survey the currently available technologies designed to improve the delivery of today's cancer chemotherapeutic agents. The authors review both the theoretical and practical considerations governing conventional and nonconventional methods of drug administration, and identify promising opportunities for product development. In their outline and discussion of the use of novel formulation technologies-including synthetic polymers and biomaterials for prolonged or sustained drug release to achieve potentially greater therapeutic effect-they profile those technologies that have resulted in a number of approved and late-stage clinical products.
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