Автор: Brown Название: Genomes 3 ISBN: 0815341385 ISBN-13(EAN): 9780815341383 Издательство: Taylor&Francis Цена: 64310 T Наличие на складе: Нет в наличии. Описание: Covering molecular genetics from the basics through to genome expression and molecular phylogenetics, "Genomes 3" is the latest edition of this pioneering textbook. Newly updated to incorporate the recent major advances, "Genomes 3" is an invaluable companion for any undergraduate throughout their studies in molecular genetics. "Genomes 3" builds on the achievements of the previous two editions by putting genomes, rather than genes, at the centre of molecular genetics teaching. Recognising that molecular biology research was being driven more by genome sequencing and functional analysis than by research into genes, this approach has gathered momentum in recent years. One of the outstanding features is the clarity of style and presentation. The artwork has been entirely re-drawn for the third edition, with the emphasis throughout on simplicity and scientific consistency. The text likewise avoids any over-complication of the subject matter. "Genomes 3" provides the reader with a simple and elegant treatment of this fast-moving and rapidly expanding field. The features include: two new chapters on genome anatomies, covering the latest sequencing achievements; new chapter on genome function, to describe the latest technologies used in studying the transcriptome and the proteome; new chapter on recombination, providing expanded coverage of genome evolution; major restructuring of chapter order, to align the book more closely to the practical reality of molecular genetics courses; newly designed and significantly expanded end-of-chapter exercises, including multiple choice questions and innovative figure tests; newly re-drawn artwork, with the emphasis throughout on simplicity and scientific consistency; and a free CD-ROM of the artwork supplied with every copy.
Автор: T. Brown Название: Genomes 4 ISBN: 0815345089 ISBN-13(EAN): 9780815345084 Издательство: Taylor&Francis Рейтинг: Цена: 64300.00 T Наличие на складе: Нет в наличии. Описание:
Genomes 4 has been completely revised and updated. It is a thoroughly modern textbook about genomes and how they are investigated. As with Genomes 3, techniques come first, then genome anatomies, followed by genome function, and finally genome evolution. The genomes of all types of organism are covered: viruses, bacteria, fungi, plants, and animals including humans and other hominids.
Genome sequencing and assembly methods have been thoroughly revised including a survey of four genome projects: human, Neanderthal, giant panda, and barley. Coverage of genome annotation emphasizes genome-wide RNA mapping, with CRISPR-Cas 9 and GWAS methods of determining gene function covered. The knowledge gained from these techniques forms the basis of the three chapters that describe the three main types of genomes: eukaryotic, prokaryotic (including eukaryotic organelles), and viral (including mobile genetic elements). Coverage of genome expression and replication is truly genomic, concentrating on the genome-wide implications of DNA packaging, epigenome modifications, DNA-binding proteins, non-coding RNAs, regulatory genome sequences, and protein-protein interactions. Also included are applications of transcriptome analysis, metabolomics, and systems biology. The final chapter is on genome evolution, focusing on the evolution of the epigenome, using genomics to study human evolution, and using population genomics to advance plant breeding. Established methods of molecular biology are included if they are still relevant today and there is always an explanation as to why the method is still important.
Each chapter has a set of short-answer questions, in-depth problems, and annotated further reading. There is also an extensive glossary. Genomes 4 is the ideal text for upper level courses focused on genomes and genomics.
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