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ABC Proteins, Holland


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Цена: 171940.00T
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Автор: Holland
Название:  ABC Proteins
Перевод названия: Белки АВС
ISBN: 9780123525512
Издательство: Elsevier Science
Классификация:


ISBN-10: 0123525519
Обложка/Формат: Hardcover
Страницы: 672
Вес: 2.01 кг.
Дата издания: January 7, 2003
Ссылка на Издательство: Link
Поставляется из: Европейский союз
Описание: ABC proteins (ATP-Binding Cassette proteins) transport a variety of molecules across membranes. They comprise one of the largest protein families known - 56 members have been identified in humans alone. Different ABC proteins transport a remarkably varied range of vital molecules across membranes, from small molecules such as chloride ions through to large molecules such as cholesterol, anti-cancer drugs and bacterial toxins. Many mammalian ABC are of considerable medical importance and are implicated in genetic diseases such as heart disease, cystic fibrosis, Stargardts retinal dystrophy and adrenoleukodystrophy. Others are involved in the immune system, lung function, the arterial system, digestive system, kidney and liver function, apoptosis, retinal function, clinical multiple drug resistance, tumour cell growth and in infectious agents. The same family of proteins is also found in bacteria, fungi, insects, plants and mammals. In bacteria, ABC transporters are not only required for nutrient uptake, but are implicated in toxin and protease secretion, as well as multiple antibiotic resistance. The family is one of the fastest growing protein groups, and research - especially given the medical importance of these proteins - is increasing at an exponential rate. For instance, the number of NIH grants concerning ABC Proteins has risen 11-fold in the last 10 years. The pace is accelerating, and is expected to continue. This title forms an in depth analysis of all we know about ABC Proteins to date.
Дополнительное описание: Кол-во стр.: 672
Формат: 270 x 200
Дата издания: 2002
Страна: UK
Круг читателей: academic, specialist
Иллюстрации: Colour illustrations
Вес: 2010



How proteins work

Автор: Williamson, Mike
Название: How proteins work
ISBN: 0815344465 ISBN-13(EAN): 9780815344469
Издательство: Taylor&Francis
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Цена: 81650.00 T
Наличие на складе: Нет в наличии.
Описание:

How Proteins Work is an up-to-date and authoritative account of protein function in living systems, explained within the governing parameters of physics, chemistry, and evolution. This text will enable advanced undergraduate students in biochemistry and biophysics to understand the relationships among protein function, structure, and dynamics. It will also serve as a valuable resource for graduate students and researchers looking for a reference on the fundamentals underlying protein function.

By providing an integrated view of proteins at both a cellular and systemic level, this textbook shows how evolution drives proteins to adopt domain structures that combine to achieve biological outcomes. The association of proteins into dimers, molecular machines, and multi-enzymatic complexes enables them to achieve catalytic and functional efficiency.


HPLC of Peptides and Proteins / Methods and Protocols

Автор: Aguilar Marie-Isabel
Название: HPLC of Peptides and Proteins / Methods and Protocols
ISBN: 0896039773 ISBN-13(EAN): 9780896039773
Издательство: Springer
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Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: Hands-on experts from academia and industry comprehensively describe how to successfully perform all the critical HPLC techniques needed for the analysis of peptides and proteins. The methods range from commonly used techniques to those for capillary to large-scale preparative isolation. The authors have also presented a number of specific applications as case studies to illustrate the analytical approaches to a particular separation or assay challenge, with examples drawn from contemporary fields in biochemistry and biotechnology.

Mass Spectrometry of Proteins and Peptides

Автор: Chapman John R.
Название: Mass Spectrometry of Proteins and Peptides
ISBN: 089603609X ISBN-13(EAN): 9780896036093
Издательство: Springer
Цена: 102440.00 T
Наличие на складе: Поставка под заказ.
Описание: John R. Chapman recreates the success of his earlier acclaimed book (Protein and Peptide Analysis by Mass Spectrometry, 1996) with a major new collection of cutting-edge methods in the analysis of proteins and peptides. Contributed by well-established investigators, each chapter provides background information before guiding the researcher step-by-step through the experimental process, with detailed instructions to help assure experimental success. The applications covered range widely and include protein sequencing, higher-order structure determination, epitope mapping, kinetics, quantitation, glycosylation analysis, and bacterial typing. Authoritative and eminently practical, Mass Spectrometry of Proteins and Peptides demonstrates the full scope of this versatile analytical technique. All protein chemists and biochemists, as well as bioanalytical scientists, who want to exploit these powerful methods in their work, will find this book indispensable.

Molecular Modeling of Proteins

Автор: Kukol Andreas
Название: Molecular Modeling of Proteins
ISBN: 1588298647 ISBN-13(EAN): 9781588298645
Издательство: Springer
Рейтинг:
Цена: 158380.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: offers introductions and methods applicable to problems faced by non-specialists - especially those new to the software packages used in molecular modeling. This book provides tips on troubleshooting and avoiding common pitfalls, along with chapters covering a range of subjects ranging from free energy calculation to applications for drug design.

Therapeutic Proteins / Methods and Protocols

Автор: Smales C. Mark, James David C.
Название: Therapeutic Proteins / Methods and Protocols
ISBN: 1588293904 ISBN-13(EAN): 9781588293909
Издательство: Springer
Рейтинг:
Цена: 186330.00 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: World-class researchers share their innovative and proven techniques for the production of therapeutic proteins downstream of the discovery stage. The methods use a variety of sources for producing therapeutic proteins, including bacterial and yeast expression systems, and insect and mammalian cells, and then cover the purification of the resulting protein using both state-of-the-art and traditional methods, such as those sourced from plasma. Additional chapters offer methods for the characterization of therapeutic proteins throughout the production process, along with methods and strategies for viral inactivation and protein formulation. The protocols follow the successful Methods in Molecular Biologyв„ў series format, each offering step-by-step laboratory instructions, an introduction outlining the principles behind the technique, lists of the necessary equipment and reagents, and tips on troubleshooting and avoiding known pitfalls.


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