Автор: Leon Rosenberg Название: Human Genes and Genomes, ISBN: 0123852129 ISBN-13(EAN): 9780123852120 Издательство: Elsevier Science Рейтинг: Цена: 54230.00 T Наличие на складе: Есть Описание: Presents the study of genes and genomics that explores all aspects of the life with relevance in the lab, in the doctor`s office, in the courtroom and even in social relationships. This book communicates the importance of genes and genomics studies in all aspects of life.
Автор: Turksen Название: Genome Editing ISBN: 3319341464 ISBN-13(EAN): 9783319341460 Издательство: Springer Рейтинг: Цена: 130430.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
This timely volume explores the use of CRISPR-Cas9 for genome editing, presenting cutting-edge techniques and their applications in treatment of disease. The chapters describe latest methods such as use of targetable nucleases, investigation of the non-coding genome, mouse genome editing, increasing of knock-in efficiency in mouse zygotes, and generation of reporter stem cells; the text contextualizes these methods in treatment of cardiovascular disease, diabetes mellitus, retinitis pigmentosa, and others. The final chapters round out the book with a discussion of controversies and future directions.
Genome Editing is an essential, of-the-moment contribution to this rapidly growing field. Drawing from a wealth of international perspectives, it presents novel techniques and applications for the engineering of the human genome. This book is essential reading for all clinicians and researchers in stem cells, regenerative medicine, genomics, biochemical and biomedical engineering- especially those interested in learning more about genome editing and applying it in a targeted, specific way.
Автор: Dennis Название: The Human Genome.2001 ISBN: 0333971434 ISBN-13(EAN): 9780333971437 Издательство: Palgrave Рейтинг: Цена: 23590.00 T Наличие на складе: Нет в наличии. Описание: The sequencing of the human genome has been hailed as the most ground breaking scientific event of the new century. It offers the exciting prospect of fresh insights into our collective history, our shared identity and our individuality, and opens up important possibilities for the identification, treatment and prevention of disease. Not since Crick and Watson's seminal paper on the structure of DNA has a scientific publication been greeted with so much public expectation for a new understanding of the basis of life itself. In this illustrated account, written and compiled by Carina Dennis and Richard Gallagher of "Nature", thenome project is made accessible for a general readership. It offers an introduction to the basic biology and techniques, a guide to the main players and events in the history of genetic science, and a range of viewpoints on its impact and reception around the world, in addition to the full text of the research paper itself.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9048134706 ISBN-13(EAN): 9789048134700 Издательство: Springer Рейтинг: Цена: 191560.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Nasheuer Название: Genome Stability and Human Diseases ISBN: 9400731256 ISBN-13(EAN): 9789400731257 Издательство: Springer Рейтинг: Цена: 191550.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This comprehensive overview discusses cancer cell biology in relation to Genome stability and Cell cycle regulation. Chapters are devoted to genome stability and anti-cancer drug targets, chromatin factors, DNA repair, apoptosis and other key areas of research.
Автор: Richardson Sarah S. Название: Sex Itself: The Search for Male and Female in the Human Genome ISBN: 022632561X ISBN-13(EAN): 9780226325613 Издательство: Wiley Рейтинг: Цена: 25350.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Human genomes are 99.9 percent identical--with one prominent exception. Instead of a matching pair of X chromosomes, men carry a single X, coupled with a tiny chromosome called the Y. Tracking the emergence of a new and distinctive way of thinking about sex represented by the unalterable, simple, and visually compelling binary of the X and Y chromosomes, Sex Itself examines the interaction between cultural gender norms and genetic theories of sex from the beginning of the twentieth century to the present, postgenomic age. Using methods from history, philosophy, and gender studies of science, Sarah S. Richardson uncovers how gender has helped to shape the research practices, questions asked, theories and models, and descriptive language used in sex chromosome research. From the earliest theories of chromosomal sex determination, to the mid-century hypothesis of the aggressive XYY supermale, to the debate about Y chromosome degeneration, to the recent claim that male and female genomes are more different than those of humans and chimpanzees, Richardson shows how cultural gender conceptions influence the genetic science of sex. Richardson shows how sexual science of the past continues to resonate, in ways both subtle and explicit, in contemporary research on the genetics of sex and gender. With the completion of the Human Genome Project, genes and chromosomes are moving to the center of the biology of sex. Sex Itself offers a compelling argument for the importance of ongoing critical dialogue on how cultural conceptions of gender operate within the science of sex.
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