Proteomics Approaches to Unravel Virus - Vertebrate Host Interactions, 109, 

Автор: Pal Chaudhuri Parimal, Ghosh Soumyabrata, Dutta Adip
Название: A New Kind of Computational Biology: Cellular Automata Based Models for Genomics and Proteomics
ISBN: 9811346585 ISBN-13(EAN): 9789811346583
Издательство: Springer
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Цена: 36770 T
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Описание: This book reflects more than three decades of research on Cellular Automata (CA), and nearly a decade of work on the application of CA to model biological strings, which forms the foundation of `A New Kind of Computational Biology` pioneered by the start-up, CARLBio.

Автор: Valeria Severino
Название: Proteomics Applications in Food Science
ISBN: 1773611364 ISBN-13(EAN): 9781773611365
Издательство: Eurospan
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Цена: 114400 T
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Описание: In the last decades, proteomics has rapidly advanced with novel developments and cutting-edge approaches, resulting in reliable platforms widely used for several purposes. Among others, food science represents one of the most dynamic and growing research areas in which proteomics is extensively applied. Food proteomics is commonly used to characterize raw materials, determine the food composition and evaluate the relationship between the food protein content and the nutritional properties. Moreover, quality control during food production can be monitored with proteomics, along with food traceability, quality and safety, in particular by detecting the presence of allergens or contaminants. Considering the complexity of food matrices and the elevated variability of food-associated proteins and peptides, it is hard to choose a single proteomic strategy. Often, a combination of multiple techniques achieves the better results, with proteomic approaches well adapted to each problem.This book covers several aspects of proteomics in food science, highlighting a range of methods and applications for analyzing the food composition, the presence of specific allergens or microorganisms, and for evaluating food identity and quality. To this aim, the book is organized into three Sections.In Section 1 are reviewed technical aspects at the basis of proteomics, focusing on concepts and challenges of proteomic analyses, sample preparation and techniques commonly used such as one- and two-dimensional electrophoresis, chromatography and mass spectrometry.In Section 2 are reported proteomic applications in food science, emphasizing on food authentication, for example producing a fingerprint typical of each food or food component. Moreover, this Section contains some interesting applications such as the identification of milk components in ancient food and the use of proteomics to evaluate ex vivo protein modifications and their effects on foods.Finally, the Section 3 focuses on proteomics and food allergies, a particularly dynamic field also called food allergenomics. Here are reported some particular proteomic applications to assess the physicochemical properties of food allergens.

Автор: Zhang
Название: Molecular Dynamics Analyses of Prion Protein Structures
ISBN: 9811088144 ISBN-13(EAN): 9789811088148
Издательство: Springer
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Цена: 147110 T
Наличие на складе: Невозможна поставка.
Описание: firstly, this book well address all PrP strong immunity species (such as rabbits, dogs, horses, water buffaloes, pigs, chicken, turtles, frogs), compared with high susceptibility species. Secondly, all the mutants of mouse PrP and human PrP are well studied by this book.

Автор: Neil Woodford; Alan P. Johnson
Название: Genomics, Proteomics, and Clinical Bacteriology
ISBN: 1617374288 ISBN-13(EAN): 9781617374289
Издательство: Springer
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Цена: 106650 T
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Описание: It is our hope that Genomics, Proteomics, and Clinical Bacteriology: Methods and Reviews will play a part in bringing such a development to fruition. These topics, and others, are considered in Genomics, Proteomics, and Clinical Bacteriology: Methods and Reviews.

Автор: Andr? L.S. Santos; Marta H. Branquinha; Claudia M.
Название: Proteins and Proteomics of Leishmania and Trypanosoma
ISBN: 9402407499 ISBN-13(EAN): 9789402407495
Издательство: Springer
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Цена: 109980 T
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Описание: Preface.- Biology of Human Pathogenic Trypanosomatids: Epidemiology, Lifecycle and Ultrastructure.- Selection of Molecular Targets for Drug Development against Trypanosomatids.- A2 and other visceralizing proteins of Leishmania: role in pathogenesis and application for vaccine development.- Arginase in Leishmania.- The heat shock proteins of Trypanosoma cruzi.- The Gp82 Surface Molecule of Trypanosoma cruzi Metacyclic Forms.- The Gp85 Surface Glycoproteins from Trypanosoma cruzi.- Trypanosoma cruzi Trans-Sialidase: Structural Features and Biological Implications.- Surface Topology Evolution of Trypanosoma Trans-Sialidase.- Ecto-Nucleotidases and Ecto-Phosphatases from Leishmania and Trypanosoma Parasites.- Gp63 Function in the Interaction of Trypanosomatids with the Invertebrate Host - Facts and Prospects.- Highlights on Trypanosomatid Aminoacyl-tRNA Synthesis.- The Expected Outcome of the Trypanosoma cruzi Proteomic Map: a Review of its Potential Biological Applications for Drug Target Discovery.- Proteomics advances in the study of Leishmania parasites and leishmaniasis.- Towards the Phosphoproteome of Trypanosomatids. Index.

Автор: Andr? L.S. Santos; Marta H. Branquinha; Claudia M.
Название: Proteins and Proteomics of Leishmania and Trypanosoma
ISBN: 9400773048 ISBN-13(EAN): 9789400773042
Издательство: Springer
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Цена: 137480 T
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Автор: Graham
Название: HIV-1 Proteomics
ISBN: 1493965409 ISBN-13(EAN): 9781493965403
Издательство: Springer
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Цена: 102970 T
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Описание: The development of proteomic analyses using advanced mass spectrometry techniques has revolutionized the way proteins are studied, namely, as individual molecules within a complex system. HIV-1 Proteomics: From Discovery to Clinical Application comprehensively covers protein analysis from the early classic experimental days to current state-of-the-art HIV-1 proteomics in a clear informative style that brings expert-level understanding to the novice. Discussion of important clinical applications and future directions for the field also make this an ideal read for the expert. After finishing this book, the reader will have a complete and functional understanding of protein analysis from traditional biochemistry to modern proteomics.

Автор: Bostjan Kobe; Mitchell Guss; Thomas Huber
Название: Structural Proteomics
ISBN: 1617377899 ISBN-13(EAN): 9781617377891
Издательство: Springer
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Цена: 121360 T
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Описание: This volume includes chapters describing, in-depth, the individual steps in the Structural Genomics pipeline, as well as less detailed overviews of individual Structural Genomics initiatives.

Название: Conformational proteomics of macromolecular architecture: approaching the structure of large molecular assemblies and their mechanisms of action (with cd-rom)
ISBN: 9812386149 ISBN-13(EAN): 9789812386144
Издательство: World Scientific Publishing
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Цена: 71690 T
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Описание: Biological processes involving large macromolecular assemblies are thought to be a dynamic consequence of cooperativity and metastability. The folding of a peptide chain creates local environments from which "activity" can emerge. In the same way, the assembly of large molecular complexes creates dynamic features that would only be feasible in a large construct.

The biological implications of such adaptation will be explored as it applies to the static quasisymmetry situations, as well as to the dynamics of structural transitions. The current wealth of solved high-resolution complex structures makes this an appropriate time to summarize the state of the art in structural dynamics of living architectures. With contributions by leading scientists in the fields of virology, bacterial flagellum, cytoskeleton, ribosome and giant enzymes, this work presents knowledge in the various fields of structural proteomics of very large molecular assemblies, with focus on their mechanisms of action.