Автор: Buzdar Aman U. Название: Endocrine Therapies in Breast Cancer ISBN: 0199218145 ISBN-13(EAN): 9780199218141 Издательство: Oxford Academ Рейтинг: Цена: 7210.00 T Наличие на складе: Есть Описание: Breast cancer is one of the leading causes of cancer mortality in women worldwide. For patients with hormone receptor-positive breast cancer, some form of endocrine therapy is central to managing their disease. This pocketbook summarises the latest evidence-based information on the use of endocrine therapies in the management of breast cancer.
Автор: Babiera Название: Advanced therapy of breast disease ISBN: 1607950944 ISBN-13(EAN): 9781607950943 Издательство: McGraw-Hill Рейтинг: Цена: 159350.00 T Наличие на складе: Есть Описание: This is the first collection of essays bringing together Deleuzian philosophy and postcolonial theory. Bignall and Patton assemble some of the world`s leading figures in these fields - including Reda Bensmaia, Timothy Bewes, Rey Chow, Philip Leonard, Nick Nesbitt, John K. Noyes, Patricia Pisters, Marcelo Svirsky and Simon Tormey - to explore rich linkages between two previously unrelated areas of study. . They deal with colonial and postcolonial social, cultural and political issues in Asia, Africa, the Americas, Australia and Palestine. Topics include colonial government, nation building and ethics in the contemporary context of globalisation and decolonisation; issues relating to resistance, transformation and agency; and questions of `representation` and discursive power as practiced through postcolonial art, cinema and literature. . This book constitutes a timely intervention to debates in poststructuralist, postcolonial and postmodern studies. It will be of interest to students in cultural studies, cinema and film studies, languages and literature, political and postcolonial studies, critical theory, social and political philosophy..
Автор: Gerald Litwack Название: Hormones and Breast Cancer, ISBN: 0124166733 ISBN-13(EAN): 9780124166738 Издательство: Elsevier Science Рейтинг: Цена: 100610.00 T Наличие на складе: Есть Описание: Reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology and enzyme mechanisms. This volume focuses on hormones and breast cancer.
Автор: Shi-Ming Tu Название: The Story of Hydra: Portrait of Cancer as a Stem-Cell Disease ISBN: 1536153737 ISBN-13(EAN): 9781536153736 Издательство: Nova Science Рейтинг: Цена: 215410.00 T Наличие на складе: Невозможна поставка. Описание: The questions we ask in this book about cancer are actually quite elementary. What is the origin of cancer? Does cancer arise in any cell in the body, or only in certain cells? Is cancer a genetic or a stem-cell disease? We illustrate that cancer is a multicellular rather than a unicellular process, a cellular rather than a genetic problem, and a stem-cell rather than a somatic-cell disease. We reveal that the incredible resemblance between a cancer cell and a stem cell suggests that they are intimately related. The uncanny ingenuity of a cancer cell is also innate in a stem cell. The recognition that cancer has a stem-cell origin indicates that a stem-cell theory of cancer may be the unified theory that we need to make sense of the torrents of new data and new insights into different facets of cancer, to see how they fit together into one picture, and to disarm the disease. A stem-cell theory of cancer can potentially accept, embrace, and integrate all of its genetic, epigenetic, proteomic, and metabolic aspects. Such a unified theory can account for all cancer hallmarks, including metastasis, heterogeneity, dormancy, and immune evasion. It predicts that multimodal therapy may be more beneficial than targeted therapy, and integrated medicine more effective than precision medicine for the management of all but the simplest tumors. It predicts that when we have the correct cancer theory, clinical progress will advance by monumental leaps rather than incremental steps. Indeed, I predict that successful clinical outcomes will ultimately provide irrefutable validation that cancer is a stem-cell disease. Therefore, the thesis of this book is actually quite simple. When we have a pertinent and correct theory of the origin of cancer, all ideas, observations, experiments, and treatments will begin to fall into place and make perfect sense. We would like to convince readers that a stem-cell theory is the elusive, long-sought unified theory, the theory of all theories, of cancer.
Автор: J. Richard McIntosh Название: Understanding Cancer: An Introduction to the Biology, Medicine, and Societal Implications of this Disease ISBN: 0815345356 ISBN-13(EAN): 9780815345350 Издательство: Taylor&Francis Рейтинг: Цена: 53070.00 T Наличие на складе: Невозможна поставка. Описание: Understanding Cancer explains the biological processes that underlie cancer and inform our treatment of it. McIntosh presents stories of people touched by cancer, while maintaining precision about what is known and still unknown about cancer`s onset, development, prognosis, and current treatment.
This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic insights. Chapters in solid and hematological malignancies address stem cell biology, genetics, epigenetics and micro-environmental regulation of dormant MRD. Novel insight into technologies for molecular phenotyping of MRD and monitoring of CTCs, DTCs and cell free RNA and DNA are also addressed extensively. Five chapters explore the above concepts in solid cancers such as prostate, breast, melanoma, head and neck and esophageal. Two chapters also explore the basic mechanisms of vascular biology targeting and epigenetic mechanisms regulating pluripotency programs during dormancy. Similar biology is explored in hematological malignancies such as T-ALL, CML, AML and multiple myeloma in additional four chapters. This book is edited and prefaced by Dr. Julio Aguirre-Ghiso, an expert in dormancy and recurrence. The chapters are written by world-recognized experts Drs. Ravi Bahtia, Samir Parekh, Russel Taichman, Monica Guzman, David Hoon, Denis Schewe, Irmela Jeremias, Cyrus Ghajar, Maria Soledad Sosa and Nicholas Stoecklein. The topic of this book is of particular interest to both basic cancer cell biologists and physician scientists that are working to provide a more integrated view of the biology of MRD and to those interested in working on or learning about this paradigm. The integrated and cross-disciplinary focus of the book from biology to medicine seeks to help bridge gaps to improve cancer care and prevent recurrences.
Автор: Polyxeni Nicolopoulou-Stamati; Luc Hens; Vyvyan C. Название: Cancer as an Environmental Disease ISBN: 1402020201 ISBN-13(EAN): 9781402020209 Издательство: Springer Рейтинг: Цена: 104480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: - Controversial topic because many of the proposed solutions or policies may damage the economy in the short term in order to reap health benefits which will only become apparent several decades in the future- Each chapter is written by experts in the field throughout the world
Автор: Piсeiro Roberto Название: Circulating Tumor Cells in Breast Cancer Metastatic Disease ISBN: 3030358046 ISBN-13(EAN): 9783030358044 Издательство: Springer Цена: 93160.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is aimed to summarise the key aspects of the role of circulating tumour cells (CTCs) in breast cancer, with special attention to their contribution to tumour progression and establishment of metastatic disease.
Автор: Henderson I. Craig Название: Breast Cancer: Fundamentals of Evidence-Based Disease Management ISBN: 0199919984 ISBN-13(EAN): 9780199919987 Издательство: Oxford Academ Рейтинг: Цена: 152890.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Breast Cancer provides an in-depth understanding of the biology of breast cancer, the natural history of the disease, the use of molecular markers, the interpretation of clinical trial data, and the integration of multiple therapeutic modalities. The single most important fact about breast cancer is the great variation in its natural history and its responsiveness to therapy from one patient to another. The clinician must integrate an assessment of the patient's likely course based on clinical and pathological staging and laboratory studies with objective evidence on the benefits of therapy. The primary aim of this book is to provide the clinician with the tools to do just that. Outcomes of clinical trials and details about commonly used drug regimens, drug dosage, and the expected side effects are summarized in generous tables and figures. Medical terminology has been defined and descriptions of the evolution in our thinking and understanding of the disease are often given to provide perspective in the interpretation of evidence from current studies for busy clinicians and trainees alike.
Название: Triple-negative breast cancer ISBN: 9813277750 ISBN-13(EAN): 9789813277755 Издательство: World Scientific Publishing Рейтинг: Цена: 84480.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Triple-negative breast cancer (TNBC) represents a challenge clinically due to the lack of actionable targets coupled with an aggressive disease course and a worse prognosis compared to other breast cancer subtypes. This book covers aspects of TNBC ranging from epidemiology, biology, molecular classification, to currently available and potentially new therapeutic options for TNBC. This book contains a range of recommended resources, including recent reviews, schematic illustrations, and information for patients with TNBC.
Individuals including researchers and educators, practitioners, pharmaceutical professionals, patients as well as their family members will find this book useful.
Автор: Tan Название: Triple-Negative Breast Cancer ISBN: 3319699792 ISBN-13(EAN): 9783319699790 Издательство: Springer Рейтинг: Цена: 93160.00 T Наличие на складе: Поставка под заказ. Описание: This guide provides practical information that will assist clinicians involved in the diagnosis, assessment, treatment, and follow-up care of patients with triple-negative breast cancer. After opening chapters on the pathologic evaluation, clinical presentation, genetics, and imaging features, the full range of current treatment approaches is thoroughly reviewed from a multidisciplinary perspective. Readers will find up-to-date information and guidance on surgical management, radiation therapy, tailored adjuvant therapy, neoadjuvant treatment, systemic treatment for metastatic disease, molecular profiling, and targeted therapy. The coverage is completed by discussion of special issues in young women with triple-negative breast cancer and individualization of the management approach in older patients affected with the disease. All healthcare professionals who care for patients with triple-negative breast cancer will find the book to be an invaluable source of expert advice on the issues faced in real-world practice.
Every year, millions of people are diagnosed with thyroid cancer or thyroid nodules. In Thyroid Cancer and Thyroid Nodules In 30 Minutes, you will learn that most thyroid nodules are benign and many patients with thyroid nodules do not need surgery. Further, even if the nodule turns out to be malignant, the majority of thyroid cancers can be successfully managed with an excellent long-term prognosis.
The author of Thyroid Cancer and Thyroid Nodules In 30 Minutes is Dr. Per-Olof Hasselgren, an experienced endocrine surgeon and professor at Harvard Medical School. Over a 45-year career, he has operated on numerous patients with thyroid cancer and thyroid nodules. Using plain English, he will explain basic concepts related to thyroid cancer and thyroid nodules, including:
The anatomy and function of the thyroid gland
The role of thyroid hormones
Blood and imaging tests
Hyperthyroidism and hypothyroidism
Bethesda classifications and the risk for cancer
Management of benign nodules
Management of thyroid cancer
Thyroidectomies, thyroid lobectomies, and other types of thyroid surgery
Different types of doctors and medical specialists you may encounter
The author will also describe four cases involving patients diagnosed with thyroid nodules, including malignant nodules. He will help us follow the diagnostic workup and management options (including different types of surgeries) in a 37-year old stay-at-home mom, a 19-year old college student, a 62-year old truck driver, and a 58-year old high school teacher.
This book is not a do-it-yourself guide -- a doctor is needed to diagnose and provide medical advice. However, Thyroid Cancer and Thyroid Nodules In 30 Minutes can help you understand what your doctor is recommending and why. If you or a loved one is diagnosed with thyroid nodules, Thyroid Cancer and Thyroid Nodules In 30 Minutes can be an invaluable and expert resource.
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