Tools and Applications in Gene Therapy, Valeria Severino
Автор: Tripti Sahu, Satpal S. Bisht Название: Tools and Applications in Gene Therapy ISBN: 1773612433 ISBN-13(EAN): 9781773612430 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 137940.00 T Наличие на складе: Невозможна поставка. Описание: Packed with comprehensive tools and techniques, this book presents to the reader a detailed, yet easily accessible, description of the whole field of gene therapy. It discusses methods currently used in preclinical and clinical gene therapy describing the basic biology and potential application of viruses as gene transfer reagents. Representative strategies are provided for gene targeting and for viral or nonviral gene delivery in cancer therapy, as well as a significant number of clinical protocols for the development of novel cancer gene therapies.
Автор: Robert E. Sobol; Kevin J. Scanlon; Eirik Nestaas Название: Gene Therapy ISBN: 3662035790 ISBN-13(EAN): 9783662035795 Издательство: Springer Рейтинг: Цена: 46570.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: This book is a collection of preclinical and clinical reports on the application of gene therapy to human disease. Several reports describe both approaches currently used in gene therapy: the introduction of a wild-type gene to restore normal gene function in diseased cells, and the use of antisense molecules to hinder abnormal gene expression.
Автор: Ravin Narain Название: Polymers and Nanomaterials for Gene Therapy ISBN: 0081005202 ISBN-13(EAN): 9780081005200 Издательство: Elsevier Science Рейтинг: Цена: 162820.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание:
Polymers and Nanomaterials for Gene Therapy provides the latest information on gene therapy, a topic that has attracted significant attention over the past two decades for the treatment of inherited and acquired genetic diseases. Major research efforts are currently focused on designing suitable carrier vectors that compact and protect oligonucleotides for gene therapy.
The book explores the most recent developments in the field of polymer science and nanotechnology, and how these advancements have helped in the design of advanced materials. Non-viral vector systems, including cationic lipids, polymers, dendrimers, peptides and nanoparticles, are potential routes for compacting DNA for systemic delivery. However, unlike viral analogues that have no difficulty in overcoming cellular barriers and immune defense mechanisms, non-viral gene carriers consistently exhibit significant reduced transfection efficiency due to numerous extra- and intracellular obstacles. Therefore, biocompatibility and potential for large-scale production make these compounds increasingly attractive for gene therapy.
This book contains chapters on the engineering of polymers and nanomaterials for gene therapy, and how they can form complexes with DNA and avoid both in vitro and in vivo barriers. Other chapters describe in vitro, ex vivo, in vivo gene therapy studies, and the current issues affecting non-viral gene therapy.
Автор: Patrick Arbuthnot Название: Gene Therapy for Viral Infections ISBN: 0124105181 ISBN-13(EAN): 9780124105188 Издательство: Elsevier Science Рейтинг: Цена: 116780.00 T Наличие на складе: Невозможна поставка. Описание:
Gene Therapy for Viral Infections provides a comprehensive review of the broader field of nucleic acid and its use in treating viral infections. The text bridges the gap between basic science and important clinical applications of the technology, providing a systematic, integrated review of the advances in nucleic acid-based antiviral drugs and the potential advantages of new technologies over current treatment options.
Coverage begins with the fundamentals, exploring varying topics, including harnessing RNAi to silence viral gene expression, antiviral gene editing, viral gene therapy vectors, and non-viral vectors.
Subsequent sections include detailed coverage of the developing use of gene therapy for the treatment of specific infections, the principles of rational design of antivirals, and the hurdles that currently face the further advancement of gene therapy technology.
Автор: Hunt Название: Gene Therapy for Cancer ISBN: 1588294722 ISBN-13(EAN): 9781588294722 Издательство: Springer Рейтинг: Цена: 231990.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: The three sections of this volume present currently available cancer gene therapy techniques. In Part II, the contributors discuss strategies and targets for the treatment of cancer. Finally, in Part III, experts discuss the difficulties inherent in bringing gene therapy treatment for cancer to the clinic.
Автор: Ashwani Kumar Название: Stem Cell Biology: Fundamentals ISBN: 1680945386 ISBN-13(EAN): 9781680945386 Издательство: Mare Nostrum (Eurospan) Рейтинг: Цена: 141370.00 T Наличие на складе: Невозможна поставка. Описание: Stem cells are mother cells that have the potential to become any type of cell in the body. One of the main characteristics of stem cells is their ability to self-renew or multiply while maintaining the potential to develop into other types of cells. This text offers an introduction to the biology of stem cells.
Автор: Roland W Herzog Название: A Guide To Human Gene Therapy ISBN: 9814280909 ISBN-13(EAN): 9789814280907 Издательство: World Scientific Publishing Рейтинг: Цена: 137280.00 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Gene therapy remains one of the hottest areas of research in medicine. This book covers topics such as RNA interference, viral and non-viral gene transfer systems, treatment of hematological diseases and disorders of the central nervous system. It offers an overview of important gene transfer vectors and most extensively studied target diseases.
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