Animal Endo-SiRNAs, Andreas Werner

Автор: Andreas Werner
Название: Animal Endo-SiRNAs
ISBN: 1493909304 ISBN-13(EAN): 9781493909308
Издательство: Springer
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Цена: 139750.00 T
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Описание: Animal Endo-SiRNAs: Methods and Protocols presents a variety of approaches to investigate endo-siRNAs.

Автор: Debra J. Taxman
Название: siRNA Design
ISBN: 1493959786 ISBN-13(EAN): 9781493959785
Издательство: Springer
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Цена: 102480.00 T
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Описание: The discovery of RNA interference (RNAi) as a methodology for gene silencing has revolutionized biological research, providing an invaluable avenue for therapeutics, and small interfering RNA (siRNA) is the most common strategy utilized for enacting RNAi. siRNA Design: Methods and Protocols offers expertly crafted guidelines and protocols for the selection of siRNA targeting sequences, for the strategic incorporation of chemical modifications, and for advantageous structural modifications to the classic siRNA design. Protocols are provided for using endogenous cellular machinery to produce siRNA from optimized precursor short hairpin RNA (shRNA) and artificial microRNA (amiRNA) molecules. Strategies are also described for specific applications such as immunostimulatory siRNA that may provide therapeutic benefit against viral infections in mammals, the simultaneous targeting of multiple siRNAs, and siRNA-mediated crop virus resistance. The design of RNAi for gene silencing in embryonic, invertebrate, and plant systems requires a variety of unique approaches, several of which are described towards the end of this volume. Written for the highly successful Methods in Molecular Biology™ series, this work contains the kind of detailed description and implementation advice that guarantees successful results. Authoritative and easy to use, siRNA Design: Methods and Protocols will provide researchers, educators, clinicians, and biotech specialists with a broad understanding of the issues in RNAi and how they can be overcome strategically through design.

Название: Sirna and mirna gene silencing
ISBN: 1617379085 ISBN-13(EAN): 9781617379086
Издательство: Springer
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Цена: 135090.00 T
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Описание: In this easy-to-use and up-to-date volume, expert researchers explore the most recent advances in siRNA design, expression, delivery, in vivo imaging, and methods. The aim is to minimize siRNA`s unwanted effects and promote successful use in patients.

Автор: Isao Endo; Teruyuki Nagamune
Название: Nano/Micro Biotechnology
ISBN: 364226493X ISBN-13(EAN): 9783642264931
Издательство: Springer
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Цена: 287330.00 T
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Описание: Part I The Nano-Scale Biological Systems in Nature; The form designed by viral genome - by K. Atomic force microscopy applied to nano-mechanics of the cell - by A. Design, synthesis and biological application of fluorescentsensor molecules for cellular imaging - by K. Surface acoustic wave atomizer and electrostatic deposition - by Y.