Автор: Burton Название: The Placenta and Human Developmental Programming ISBN: 052119945X ISBN-13(EAN): 9780521199452 Издательство: Cambridge Academ Рейтинг: Цена: 63810 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: Developmental programming is a rapidly advancing discipline of great importance to basic scientists and health professionals alike. This text integrates, for the first time, contributions from world experts to explore the role of the placenta in developmental programming. The book considers the materno-fetal supply line, and how perturbations of placental development impact on its functional capacity. Chapters examine ways in which environmental, immunological and vascular insults regulate expression of conventional and imprinted genes, along with their impact on placental shape and size, transport, metabolism and endocrine function. Research in animal models is integrated with human clinical and epidemiological data, and questions for future research are identified. Transcripts of discussions between the authors allow readers to engage with controversial issues. Essential reading for researchers in placental biology and developmental programming, as well as specialists and trainees in the wider field of reproductive medicine.
Автор: Soares Michael J., Hunt Joan S. Название: Placenta and Trophoblast / Methods and Protocols, Volume I ISBN: 1588294048 ISBN-13(EAN): 9781588294043 Издательство: Springer Рейтинг: Цена: 102960 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A collection of cutting-edge laboratory techniques for the study of trophoblast and placental biology. The techniques presented range from experimental animal models, to animal and human placental organ and cell culture systems, to morphological, biochemical, and molecular strategies for assessing trophoblast/placental growth, differentiation and function. Volume 1 provides readily reproducible protocols for studying embryo-uterine implantation, trophoblast cell development, and the organization and molecular characterization of the placenta. Highlights include strategies for the isolation and culture of trophoblast cells from primates, ruminants, and rodents, and precise guidance to the molecular and cellular analysis of the placental phenotype. A companion second volume concentrates on methods for investigating placental function.
Автор: Soares Michael J., Hunt Joan S. Название: Placenta and Trophoblast / Methods and Protocols, Volume II ISBN: 1588296083 ISBN-13(EAN): 9781588296085 Издательство: Springer Рейтинг: Цена: 116320 T Наличие на складе: Есть у поставщика Поставка под заказ. Описание: A collection of cutting-edge laboratory techniques for the study of the trophoblast and placental biology. The techniques presented range from experimental animal models, to animal and human placental organ and cell culture systems, to morphological, biochemical, and molecular strategies for assessing trophoblast/placental growth, differentiation and function. Volume 2 provides readily reproducible protocols for studying trophoblast invasion, maternal immune cell responses to pregnancy, and the hormone producing capabilities of the placenta. There are also methods to investigate the barrier function of the placenta, its role in regulating the transport of nutrients and wastes, and the adaptations of trophoblast cells and the placenta to disease. Highlights include techniques to analyze trophoblast cell interactions with the uterine vasculature and immune cells, and the endocrine functions of the placenta. A companion first volume concentrates on methods for investigate embryo-uterine implantation, trophoblast cell development, and the organization and molecular characterization of the placenta.
Автор: Steven Lewis Название: Pathology of the Placenta ISBN: 0443075867 ISBN-13(EAN): 9780443075865 Издательство: Elsevier Science Цена: 85710 T Наличие на складе: Невозможна поставка. Описание: Drs. Steven H. Lewis and Eugene Perrin provide a concise overview of placental pathology and cover the latest scientific and molecular biological data relevant to placental health.
Автор: Helen Kay, MD (Editor), D. Michael Nelson, MD (Edi Название: The Placenta: From Development to Disease ISBN: 1444333666 ISBN-13(EAN): 9781444333664 Издательство: Wiley Рейтинг: Цена: 84750 T Наличие на складе: Нет в наличии. Описание: The Placenta - friend not foe The placenta is central to the survival of the fetus. Placental dysfunction, whether from disease or maldevelopment, therefore threatens the fetus and its mother. Disruption to normal placental function can disrupt fetal d
Автор: Duttaroy Название: Human Placental Trophoblasts ISBN: 148225428X ISBN-13(EAN): 9781482254280 Издательство: Taylor&Francis Рейтинг: Цена: 71540 T Наличие на складе: Поставка под заказ. Описание: Human Placental Trophoblasts: Impact of Maternal Nutrition explores the vital roles of trophoblasts play in fetal growth and pregnancy, giving you new insight into the modulation of placental trophoblast functions by nutrients. It also reviews the role of fatty acids, folic acids, and specific vitamins in this aspect. The book highlights the critical role of nutrients on human placental development and its' in utero programming effects on the development of chronic diseases such as type 2 diabetes, cardiovascular diseases, hypertension, and obesity in later life. The book begins with discussions of the central process of placentation and its regulation on size and growth of the fetus. It also covers the effects of key macronutrients on placental growth, metabolism, transport, and secretory function. The text details important vitamins and few micronutrients and their roles in the feto-placental growth and development. It includes information on the influence of maternal lifestyle and environmental factors on regulation of the growth, metabolism and gene expression in the feto-placental unit. A review of the genes linked to the process of placentation rounds out the coverage. An examination of a broad range of evidence in the areas of placental growth, function, and its impact on feto-placental outcome, the book presents new knowledge on nutrition and its relevance with early human development. This includes not only the effects of maternal nutrients on possible neonatal growth and development but also their regulation by maternal lifestyle associated factors. A fine blending of epidemiology, clinical nutrition, perinatal and neonatal medicine, and biochemistry and molecular biology areas of research activities, the book helps you to understand the impact of maternal nutrition on placentation and its relevance with pregnancy outcome and fetal programming of adult health and disease.