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Notch Regulation of the Immune System, Radtke

Автор: Radtke
Название:  Notch Regulation of the Immune System
Издательство: Springer
Классификация:
Иммунология

ISBN: 3642242936
ISBN-13(EAN): 9783642242939
ISBN: 3-642-24293-6
ISBN-13(EAN): 978-3-642-24293-9
Обложка/Формат: Hardback
Страницы: 184
Вес: 0.461 кг.
Дата издания: 01.08.2012
Серия: Current Topics in Microbiology and Immunology
Язык: ENG
Издание: 2012 ed.
Иллюстрации: X, 200 p. 26 illus., 24 in color.
Размер: 235 x 155 x 15
Читательская аудитория: Professional & vocational
Рейтинг:
Поставляется из: Германии
Описание: Notch signaling regulates many cell fate decision and differentiation processes during embryonic development and tissue homeostasis. Moreover, disregulation of the pathway is associated with human disorders and cancer. In the last 15 years it became evident that Notch plays important roles in the hematopoietic system as well as in the regulation of immune responses. This special issue on Notch regulation of the immune system summarizes recent advances and covers multiple aspects of Notch signaling within the hematopoietic and the immune system.  This issue covers subjects including Notch function in embryonic and adult hematopoietic stem cells, lymphocyte development and function as well as in T cell leukemia.
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Basic Immunology, Functions and Disorders of the Immune System, 5th Edition

Автор: Abul K. Abbass, Andrew H. H. Lichtman, Shiv Pillai
Название: Basic Immunology, Functions and Disorders of the Immune System, 5th Edition
ISBN: 032339082X ISBN-13(EAN): 9780323390828
Издательство: Elsevier Science
Рейтинг:
Цена: 30050 T
Наличие на складе: Есть

Primer to the Immune Response

Автор: Mak Tak
Название: Primer to the Immune Response
ISBN: 0123847435 ISBN-13(EAN): 9780123847430
Издательство: Elsevier Science
Рейтинг:
Цена: 32250 T
Наличие на складе: Невозможна поставка.
Описание: Now available with the most current and relevant research from Cell Press, Mak's Primer to the Immune Response, Academic Cell Update Edition, gives readers both the concepts and the applications students need to know to fully grasp Immunology. Mak introduces basic concepts and then follows with specific applications in research today. This book is further enhanced by its inclusion in the Academic Cell collaboration, providing it with links to current and recently published research.
Now with an online study guide with the most current, relevant research from Cell PressFull supplements including test bank, powerpoint and online self quizzingColor illustrations enhance key topics and concepts

Immune Rebalancing: The Future of Immunosuppression

Автор: Diana Boraschi
Название: Immune Rebalancing: The Future of Immunosuppression
ISBN: 0128033029 ISBN-13(EAN): 9780128033029
Издательство: Elsevier Science
Рейтинг:
Цена: 40040 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание:

Immune Rebalancing: The Future of Immunosuppression summarizes the most promising perspectives of immunopharmacology, in particular in the area of immunosuppression by considering molecular pathways, personalized medicine, microbiome and nanomedicine.

Modulation of immune responses for therapeutic purposes is a particularly relevant area, given the central role of anomalous immunity in diseases. These diseases vary from the most typically immune-related syndromes (autoimmune diseases, allergy and asthma, immunodeficiencies) to those in which altered immunity and inflammation define the pathological outcomes (chronic infections, tumours, chronic inflammatory and degenerative diseases, metabolic disorders, etc.

  • Visits immunosuppression from a modern point of view of signalling mechanisms at the light of the current knowledge of signalling mechanisms and regulatory networks allows the reader to formulate new ideas and concepts on how to use immunosuppression the therapeutic purposes
  • Encourages researchers to engage into exploring the field of pharmacological modulation of immune responses in depth, and with the new knowledge and tools available, designs more effective therapeutic strategies to autoimmune and inflammatory diseases, cancer, degenerative diseases and infections
  • Examines the link between molecular pathways associated to immune-suppression and the new immunopharmacology approaches
  • Provides information on the new strategies for drug development in this field
  • Considers the role of microbes in the development of the mammalian immune system and immune responses, which will widen the reader's strategy for addressing therapeutic immune modulations

The Innate Immune System: Strategies for Disease Control ,1285

Автор: Masaru Taniguchi
Название: The Innate Immune System: Strategies for Disease Control ,1285
ISBN: 0444519815 ISBN-13(EAN): 9780444519818
Издательство: Elsevier Science
Цена: 64560 T
Наличие на складе: Невозможна поставка.
Описание: "The Innate Immune System: Strategies for Disease Control" is the result of proceedings the Uehara Memorial Foundation Symposium held in Tokyo, Japan. The latest research on molecular events in innate immunity and the interface between innate and acquired immunity was discussed at the symposium. The book contains 30 papers contributed by prominent investigators in the field of innate immunology, and is divided into 3 themes; Receptor signalling and functio in innate immune responses; Interface between innate and acquired immunity and Manipulation of the innate immune system and new strategies for disease control.

It was the explicit aim of the symposium to increase understanding in these fields, and further aid the development of novel strategies for disease control in the 21st Century. "The Innate Immune System: Strategies for Disease Control" will be of particular interest to immunologists, medical students, biomedical researchers and microbiologists alike.

The Immune System: Allergic Response Anatomical Chart

Автор: Acc
Название: The Immune System: Allergic Response Anatomical Chart
ISBN: 1587799731 ISBN-13(EAN): 9781587799730
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 3420 T
Наличие на складе: Поставка под заказ.
Описание: This is the first in a series of four Anatomical Charts that provides an overview of the major responses of the immune system. This chart focuses on the allergic response. We will soon be publishing charts on the autoimmune response, the infectious response, and the cancer response.

The Immune System: Allergic Response Anatomical Chart

Автор: Acc
Название: The Immune System: Allergic Response Anatomical Chart
ISBN: 158779974X ISBN-13(EAN): 9781587799747
Издательство: Lippincott Williams & Wilkins
Рейтинг:
Цена: 6810 T
Наличие на складе: Поставка под заказ.
Описание: This is the first in a series of four Anatomical Charts that provides an overview of the major responses of the immune system. This chart focuses on the allergic response. We will soon be publishing charts on the autoimmune response, the infectious response, and the cancer response.

Innate Immune System

Автор: Kaufmann He Stefan, Lyczak B Jeffery, Wetzler M Le
Название: Innate Immune System
ISBN: 1555812910 ISBN-13(EAN): 9781555812911
Издательство: Wiley
Рейтинг:
Цена: 48520 T
Наличие на складе: Поставка под заказ.
Описание: Covering various aspects of innate immunity with an emphasis on response to infectious agents, this book focuses on evolutionary aspects, describing the major cells, humoral factors, receptors, and effector responses central to innate immunity. It is useful for scientists and students active in several areas of immunology and microbiology.

Mechanisms of Lymphocyte Activation and Immune Regulation X / Innate Immunity

Автор: Gupta Sudhir, Paul William E. , Steinman Ralph
Название: Mechanisms of Lymphocyte Activation and Immune Regulation X / Innate Immunity
ISBN: 0387241884 ISBN-13(EAN): 9780387241883
Издательство: Springer
Рейтинг:
Цена: 127450 T
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Описание: Mechanisms of Lymphocyte Activation and Immune Regulation X: Innate Immunity is the proceedings of the Xth International Conference on Mechanisms of Lymphocyte Activation and Immune Regulation: Innate Immunity, held February 6-8, 2004 in Newport Beach, California. It is the tenth volume of its kind to appear in the series Advances in Experimental Medicine and Biology. Topics include toll receptors, dendritic cells, NK cells, and complement receptors.

Wang (Ed), Innate Immune Regulation and Cancer Immunotherapy

Название: Wang (Ed), Innate Immune Regulation and Cancer Immunotherapy
ISBN: 1441999132 ISBN-13(EAN): 9781441999139
Издательство: Springer
Рейтинг:
Цена: 104020 T
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Описание: Innate and adaptive immunity play important roles in immunosurveillance and tumor destruction. However, increasing evidence suggests that tumor-infiltrating immune cells may have a dual function: inhibiting or promoting tumor growth and progression. Although regulatory T (Treg) cells induce immune tolerance by suppressing host immune responses against self- or non self-antigens, thus playing critical roles in preventing autoimmune diseases, they might inhibit antitumor immunity and promote tumor growth. Recent studies demonstrate that elevated proportions of Treg cells are present in various types of cancers and suppress antitumor immunity. Furthermore, tumor-specific Treg cells can inhibit immune responses only when they are exposed to antigens presented by tumor cells. Therefore, Treg cells at tumor sites have detrimental effects on immunotherapy directed to cancer.

Mechanisms of Lymphocyte Activation and Immune Regulation XI

Автор: Sudhir Gupta; Frederick W. Alt; Max D. Cooper; Fri
Название: Mechanisms of Lymphocyte Activation and Immune Regulation XI
ISBN: 1441942831 ISBN-13(EAN): 9781441942838
Издательство: Springer
Рейтинг:
Цена: 104020 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: In recent years, major developments have increased understanding of various genetic and epigenetic regulatory processes that are critical for the generation of B cell repertoires.

Immune Regulation and Immunotherapy in Autoimmune Disease

Автор: Zhang Jingwu
Название: Immune Regulation and Immunotherapy in Autoimmune Disease
ISBN: 0387360026 ISBN-13(EAN): 9780387360027
Издательство: Springer
Рейтинг:
Цена: 97390 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: This volume will review the most recent advances in the understanding of cellular and molecular mechanisms for immune responses and immune regulation. Chapters in the first portion of this book will discuss the theoretical basis for current immunotherapies for autoimmune diseases. The second portion of the book will provide an updated review on the research behind the clinical trials/immunotherapies (e.g. T-cell vaccination, antibody therapy, etc.) in the areas of autoimmune diseases by the principal investigators of these studies. These chapters will discuss clinical and basic research as well as immunological data in the context of cellular and molecular mechanisms of the therapies. The book will finish with chapters by leaders in the field who will provide expert views on challenges and future directions.

Lymphocyte Activation and Immune Regulation IX / Homeostasis and Lymphocyte Traffic

Автор: Gupta Sudhir, Butcher Eugene, Paul William E.
Название: Lymphocyte Activation and Immune Regulation IX / Homeostasis and Lymphocyte Traffic
ISBN: 030647395X ISBN-13(EAN): 9780306473951
Издательство: Springer
Рейтинг:
Цена: 111310 T
Наличие на складе: Есть у поставщика Поставка под заказ.
Описание: During the past five years major progress has been made in understanding the basic mechanisms of lymphocyte homeostasis and in the developmental relationship between different memory T subsets and their traffic patterns and functional significance. This volume highlights the current concepts of lymphocyte development, factors regulating lymphocyte trafficking and development, and specialized characteristics and functional properties of naive and memory subsets. This volume is divided into three sections. Section I deals with factors that regulate the development and maturation of T cells and B cells and lymphocyte traffic. The significance of C-kit, Bcl-6, IL-7, and Vav in the development of T and B lymphocytes is discussed. A role of lymphotoxins and VAP-I in trafficking of leucocytes is reviewed. Finally, the trafficking and homing characteristics of T cell and B cell subsets, and the regulation of these processes during the immune response, is presented. Section II discusses various aspects of naive and memory T cell biology, including clonal expansion, reprogramming of genes including those encoding cytokines and cytotoxic granules, changes in the expression of cell surface proteins involved in cell-cell adhesion, homing of naive and memory T cells, the role of MHC and cytokines in the maintenance of naive and memory T cells, and the characterization and differentiation of virus-specific memory T cell heterogeneity in mice and humans. Novel methods of visualization of immune cells and immune systems are reviewed in Section III. This includes tracking of dendritic cells in vivo, monitoring arterial smooth muscle-specific T cells in the inflamed vasculature, imaging of molecular migrations in immune synapses, and visualization of various immune cells in intact lymphoid tissues by two photon confocal imaging. This volume should be of interest to immunologists, molecular biologists, microbiologists, pathologists, academic physicians, cell biologists, and scientists and clinicians interested in vaccine development.


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